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9-Fluoro-16a,17-(isopropylidenedioxy)corticosterone

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9-Fluoro-16a,17-(isopropylidenedioxy)corticosterone Basic information

Product Name:
9-Fluoro-16a,17-(isopropylidenedioxy)corticosterone
Synonyms:
  • 9-fluoro-11b,21-dihydroxy-16a,17-(isopropylidenedioxy)pregn-4-ene-3,20-dione
  • 9-Fluoro-16a,17-(isopropylidenedioxy)corticosterone
  • 9-fluoro-11beta,21-dihydroxy-16alpha,17-(isopropylidenedioxy)pregn-4-ene-3,20-dione
  • 9α-FLUORO-11β,16α,17α,21-TETRAHYDROXY-PREGNA-4-ENE-3,20-DIONECYCLIC16,17-ACETAL
  • 9-Fluoro-11β,21-dihydroxy-16α,17-[(1-methylethylidene)bis(oxy)]pregn-4-ene-3,20-dione
  • 9-Fluoro-16α,17-(isopropylidenedioxy) Corticosterone
  • 9-fluoro-11β,21-dihydroxy-16α,17-(isopropylidenedioxy)pregn-4-ene-3,20-dione
  • HydrotriaMcinolone Acetate
CAS:
1524-86-3
MF:
C24H33FO6
MW:
436.51
EINECS:
216-195-2
Product Categories:
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Steroids
Mol File:
1524-86-3.mol
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9-Fluoro-16a,17-(isopropylidenedioxy)corticosterone Chemical Properties

Melting point:
249-254°C (dec.)
Boiling point:
575.7±50.0 °C(Predicted)
Density 
1.31±0.1 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
Chloroform (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
12.87±0.10(Predicted)
color 
Pale Yellow to Light Yellow
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9-Fluoro-16a,17-(isopropylidenedioxy)corticosterone Usage And Synthesis

Chemical Properties

Pale Yellow Solid

Uses

9-Fluoro-16α,17-(isopropylidenedioxy) Corticosterone (Triamcinolone Acetonide EP Impurity E) is a synthetic fluorinated corticosteroid tested for inhibition of granuloma in rats and for vasoconstriction activity in human subjects; potential topical antiinflammatory agent.

Definition

ChEBI: 9-Fluoro-11beta,21-dihydroxy-16alpha,17-(isopropylidenedioxy)pregn-4-ene-3,20-dione is a 21-hydroxy steroid.

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