Epitiostanol
Epitiostanol Basic information
- Product Name:
- Epitiostanol
- Synonyms:
-
- 2alpha,3alpha-Epithio-5alpha-androstan-17beta-ol
- Epithioandrostanol
- Epitiostanol
- 10275S
- 2,3-Epithio-1H-cyclopenta[a]phenanthrene, androstan-17-ol deriv.
- 2α,3α-Epithio-5α-androstan-17β-ol
- 5α-Androstan-17β-ol, 2α,3α-epithio- (7CI, 8CI)
- Androstan-17-ol, 2,3-epithio-, (2α,3α,5α,17β)-
- CAS:
- 2363-58-8
- MF:
- C19H30OS
- MW:
- 306.51
- Product Categories:
-
- Inhiitors
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Steroids
- Sulfur & Selenium Compounds
- Mol File:
- 2363-58-8.mol
Epitiostanol Chemical Properties
- Melting point:
- 127-128°
- alpha
- D27.5 +24.4° (c = 1.054 in chloroform)
- Boiling point:
- 417.1°C (rough estimate)
- Density
- 1.0122 (rough estimate)
- refractive index
- 1.5700 (estimate)
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 15.10±0.60(Predicted)
- color
- White to Off-White
- Water Solubility
- 1.2mg/L(37 ºC)
Epitiostanol Usage And Synthesis
Originator
Thiodrol,Shionogi,Japan,1977
Uses
An anabolic steroid that exhibits androgenic, myogenic, anabolic, anticatabolic, progestational, deciduomatogenic, and antiestrogenic activities. An anti-estrogen with anti-mammry cancer agent.
Definition
ChEBI: Epitiostanol is an organic molecular entity.
Manufacturing Process
A solution of 2β-thiocyanato-3α-methanesulfonyloxy-5α-androstan-17β-ol 17- acetate (0.82 part by weight) and potassium hydroxide (0.9 part by weight) in diglyme (20 parts by volume) is refluxed on a water bath for 24 hours while stirring. To the reaction mixture, there is added water, and the separated substance is collected by filtration and crystallized from hexane to give 2β,3β- epithio-5α-androstan-17β-ol (0.60 part by weight) as crystals melting at 132.5°C to 134°C.
Therapeutic Function
Antineoplastic
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Epitiostanol(2363-58-8)Related Product Information
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- EPICHOLESTEROL
- STIGMASTEROL
- Sterol
- Vegetable alcohol
- DI-N-OCTYL SULFIDE
- ETHYLENE SULFIDE
- Epitiostanol
- 11-Mercapto-1-undecanol
- Mepitiostane
- CYCLOHEXENE SULFIDE
- 16-MERCAPTO-1-HEXADECANOL
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