Sophoramine
Sophoramine Basic information
- Product Name:
- Sophoramine
- Synonyms:
-
- SOPHORAMINE96%
- 11,12,13,14-Tetradehydromatridin-15-one
- Sophoramine
- Matridin-15-one, 11,12,13,14-tetradehydro-
- (4(1)S,7aS,13bS)-2,3,5,6,7,7a,8,13b-octahydro-1H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10(4(1)H)-one
- 1H,5H,10H-Dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one, 2,3,6,7,7a,8,13b,13c-octahydro-, (7aS,13bS,13cS)-
- CAS:
- 6882-66-2
- MF:
- C15H20N2O
- MW:
- 244.33
- Product Categories:
-
- Alkaloids
- reagent
- standard substance
- Mol File:
- 6882-66-2.mol
Sophoramine Chemical Properties
- Melting point:
- 164-5°C
- Boiling point:
- 455.6±34.0 °C(Predicted)
- Density
- 1.22±0.1 g/cm3(Predicted)
- pka
- 9.67±0.20(Predicted)
- NIST Chemistry Reference
- Sophoramine(6882-66-2)
Sophoramine Usage And Synthesis
Description
An alkaloid present in Sophora alopecuroides, the base possesses the tetracyclic structure characteristic of the Sophora alkaloids. It is 1aevorotatory with [α]D - 90.85° or - 98° (EtOH). It yields a series of well crystalline salts and derivatives including the hydrochloride, m.p. 247-8° (dec.); hydriodide, m.p. 294-6°C; aurichloride, m.p. 183-4°C (dec.); p1atinich1oride, m.p. 245-7°C (dec.); picrate, m.p. 229-231°C (dec.) and the picrolonate, m.p. 173-5°C (dec.).
Uses
Sophoramine is a quinolizidine alkaloid isolated from traditional Chinese herbal drugssuch as Sophora flavescens Ait. (Kushen), S. alopecuroides L. (Kudouzi or Kugancao) and S. tonkinensis Gapnep (Shandougen).
Definition
ChEBI: Sophoramine is a naphthyridine derivative.
References
Orekhov., Chern. Zentr., II, 2215 (1935)
Orekhov, Proskurnina, Konovalova., Ber., 68,431 (1935)
Proskurnina, Kuzovkov., Dokl. Akad. Nauk SSSR, 91, 1145 (1953)
Okuda et al., Chern. & Ind., 1326 (1962)
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