2-[(dimethylamino)methyl]cyclohexan-1-one Chemical Properties

Melting point:

148-150 °C

Boiling point:

222℃

Density 

0.944

refractive index 

1.4672

Flash point:

70℃

storage temp. 

2-8°C

pka

8.83±0.28(Predicted)

2-[(dimethylamino)methyl]cyclohexan-1-one Usage And Synthesis

Uses

2-(Bismethyl)aminomethylcyclohexanone is an intermediate in the synthesis of O-Desmethyl Tramadol Hydrochloride (D294750), an optically active metabolite of Tramadol.

Synthesis Reference(s)

Journal of the American Chemical Society, 98, p. 6715, 1976 DOI: 10.1021/ja00437a058
Synthetic Communications, 14, p. 585, 1984 DOI: 10.1080/00397918408059581

2-[(dimethylamino)methyl]cyclohexan-1-one(15409-60-6)Related Product Information

• 2-(Dimethylaminomethyl)-1-cyclohexanone hydrochloride
• 2-[(dimethylamino)methyl]cyclohexan-1-one
• (3AR,7AR)-OCTAHYDRO-2-[1-IMINO-2-(2-METHOXYPHENYL)ETHYL]-7,7-DIPHENYL-4H-ISOINDOL-4-ONE
• 2-(PIPERIDYLMETHYL)-1-CYCLOHEXANONE HYDROCHLORIDE
• 2-[(DIETHYLAMINO)METHYL]CYCLOHEXANONE HYDROCHLORIDE
• 2-[(N,N-DIBENZYLAMINO)METHYL]CYCLOHEXANONE, HYDROCHLORIDE
• 2-(Bistrideuteromethyl)amniomethylcyclohexanone-D6
• AKOS BBS-00000410
• Pimeclone
• SPECS AF-399/25108033
• N,N-Dimethyl-2-aminomethyl-4,4-diphenylcyclohexanone hydrochloride
• AKOS BC-0774
• SPIRO[5,5-DIMETHYL-1,3-CYCLOHEXANEDIONE-2,5'-(3'-PHENYL-2',3',4',4A',5',6'-HEXAHYDRO-1'H-PYRAZINO[1',2'-A']QUINOLINE)]
• RARECHEM AQ NN 0359
• RARECHEM AQ NN 0358
• SPIRO[5,5-DIMETHYL-1,3-CYCLOHEXANEDIONE-2,5'-(9'-CHLORO-3'-PHENYL-2',3',4',4A',5',6'-HEXAHYDRO-1'H-PYRAZINO[1',2'-A']QUINOLINE)]
• SPIRO[1,3-CYCLOHEXANEDIONE-2,5'-(3'-(2',3'-DIMETHYLPHENYL)-2',3',4',4A',5',6'-HEXAHYDRO-1'H-PYRAZINO[1,'2'-A']QUINOLINE)]
• SPIRO[5,5-DIMETHYL-1,3-CYCLOHEXANEDIONE-2,5'-(3'-BENZYL-2',3',4',4A',5',6'-HEXAHYDRO-1'H-PYRAZINO[1',2'-A']QUINOLINE)]