2-Chloro-6-hydroxymethyl-pyridin-3-ol Chemical Properties

Melting point:

133～135℃

Boiling point:

407.6±40.0 °C(Predicted)

Density 

1.493±0.06 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

pka

4.24±0.10(Predicted)

InChI

InChI=1S/C6H6ClNO2/c7-6-5(10)2-1-4(3-9)8-6/h1-2,9-10H,3H2

InChIKey

NQELPILICRHYOE-UHFFFAOYSA-N

SMILES

C1(CO)=NC(Cl)=C(O)C=C1

Safety Information

HS Code 

2933399990

2-Chloro-6-hydroxymethyl-pyridin-3-ol Usage And Synthesis

Description

2-Chloro-6-hydroxymethyl-pyridin-3-ol is a pharmaceutical intermediate compound that can be used to prepare Mcl1 inhibitors.

Uses

2-Chloro-6-(hydroxymethyl)-3-pyridinol is useful reagent for stereoselective preparation of furopyridylethylthiopyrimidine HIV-1 reverse transcriptase inhbitors.