ChemicalBook > CAS DataBase List > ST1481

ST1481

Product Name
ST1481
CAS No.
292618-32-7
Chemical Name
ST1481
Synonyms
Lbq707;ST1481;STI481;CPT 184;GIMATECAN;Unii-7kks9R192f;ST1481: GIMATECAN;LBQ707; ST1481; CPT 184;ST1481 ST-1481 Gimatecan;Gimatecan, 10 mM in DMSO
CBNumber
CB01011641
Molecular Formula
C25H25N3O5
Formula Weight
447.488
MOL File
292618-32-7.mol
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ST1481 Property

Boiling point:
780.6±70.0 °C(Predicted)
Density 
1.37±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
pka
11.20±0.20(Predicted)
form 
Solid
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H300Fatal if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H351Suspected of causing cancer

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P281Use personal protective equipment as required.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0006524
Product name
Gimatecan
Purity
99.20%
Packaging
5mg
Price
$350
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0002825
Product name
GIMATECAN
Purity
95.00%
Packaging
1G
Price
$1091.48
Updated
2021/12/16
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ST1481 Chemical Properties,Usage,Production

Biological Activity

Gimatecan (ST1481) is a potent topoisomerase I inhibitor. It is an orally active camptothecin analog with antineoplastic activity.

in vivo

Gimatecan (2 mg/kg; treatment per os, every fourth day for four times) is effective for inhibiting tumor growth.

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target

Animal Model: Athymic Swiss nude mice bearing HT1376 model
Dosage: 2 mg/kg
Administration: Treatment per os, every fourth day for four times
Result: Caused a marked tumor growth inhibition during treatment.

Topoisomerase I

ST1481 Preparation Products And Raw materials

Raw materials

Preparation Products

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ST1481 Suppliers

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View Lastest Price from ST1481 manufacturers

Career Henan Chemical Co
Product
ST1481 292618-32-7
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
200kg
Release date
2020-01-08

292618-32-7, ST1481Related Search:


  • CPT 184
  • LBQ707; ST1481; CPT 184
  • GIMATECAN
  • ST1481
  • ST1481: GIMATECAN
  • (4S)-11-((E)-((1,1-Dimethylethoxy)imino)methyl)-4-ethyl-4-hydroxy-1,12-dihydro-14H-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H)-dione
  • 1H-Pyrano(3',4':6,7)indolizino(1,2-B)quinoline-11-carboxaldehyde, 4-ethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-, 11-(o-(1,1-dimethylethyl)oxime), (C(E),4S)-
  • 7-T-Butoxyiminomethylcamptothecin
  • Lbq707
  • Unii-7kks9R192f
  • 7-[(E)-tert-butyloxyiminomethyl]-camptothecin
  • STI481
  • ST1481 ST-1481 Gimatecan
  • (S,E)-4-Ethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-11-carbaldehyde O-(tert-butyl) oxime
  • Gimatecan, 10 mM in DMSO
  • 292618-32-7