ChemicalBook > CAS DataBase List > ST1481

ST1481

Product Name
ST1481
CAS No.
292618-32-7
Chemical Name
ST1481
Synonyms
Lbq707;ST1481;STI481;CPT 184;GIMATECAN;Unii-7kks9R192f;ST1481: GIMATECAN;LBQ707; ST1481; CPT 184;ST1481 ST-1481 Gimatecan;Gimatecan, 10 mM in DMSO
CBNumber
CB01011641
Molecular Formula
C25H25N3O5
Formula Weight
447.488
MOL File
292618-32-7.mol
More
Less

ST1481 Property

Boiling point:
780.6±70.0 °C(Predicted)
Density 
1.37±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
pka
11.20±0.20(Predicted)
form 
Solid
color 
Light yellow to yellow
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H300Fatal if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H351Suspected of causing cancer

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P281Use personal protective equipment as required.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

ChemScene
Product number
CS-0006524
Product name
Gimatecan
Purity
99.20%
Packaging
5mg
Price
$350
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0002825
Product name
GIMATECAN
Purity
95.00%
Packaging
1G
Price
$1091.48
Updated
2021/12/16
More
Less

ST1481 Chemical Properties,Usage,Production

Uses

Gimatecan (ST1481) is a potent topoisomerase I inhibitor. Gimatecan is an orally bioavailable camptothecin analogue with antitumor activity[1].

Biological Activity

Gimatecan (ST1481) is a potent topoisomerase I inhibitor. It is an orally active camptothecin analog with antineoplastic activity.

in vivo

Gimatecan (2 mg/kg; treatment per os, every fourth day for four times) is effective for inhibiting tumor growth.

< div class="cpd-mod-vv">
table>

target

Animal Model: Athymic Swiss nude mice bearing HT1376 model
Dosage: 2 mg/kg
Administration: Treatment per os, every fourth day for four times
Result: Caused a marked tumor growth inhibition during treatment.

Topoisomerase I

IC 50

Topoisomerase I

References

[1] Paola Ulivi, et al. Cellular Basis of Antiproliferative and Antitumor Activity of the Novel Camptothecin Derivative, Gimatecan, in Bladder Carcinoma Models. Neoplasia. 2005 Feb;7(2):152-61. DOI:10.1593/neo.04397

ST1481 Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

ST1481 Suppliers

China 39 United States 9 Global 48
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9510
Advantage
58
Tel
86-021-61559134 15921386130
Fax
021-55068248
Email
3423497944@qq.com
Country
China
ProdList
8144
Advantage
55
Tel
21-619849051-1 18521059765
Email
synchempharma@aliyun.com
Country
China
ProdList
6468
Advantage
55
Tel
Fax
-
Email
eric_feng1954@126.com
Country
China
ProdList
9248
Advantage
55
Tel
021-61847300 13341622919
Fax
021-61847300
Email
shcss01@163.com
Country
China
ProdList
4808
Advantage
58
Tel
+86-021-51783479 +86-13816874662
Fax
021-50800795
Email
info@shochem.com
Country
China
ProdList
307
Advantage
58
Tel
+1-2135480471
Email
sales@sarms4muscle.com
Country
China
ProdList
10473
Advantage
58
Tel
18871490254
Fax
027-59599243
Email
linda@hubeijusheng.com
Country
CHINA
ProdList
28172
Advantage
58
Tel
18616526224
Email
lianshuo@vip.126.com
Country
China
ProdList
9607
Advantage
58
Tel
86-21-50800795
Email
info@shochem.com
Country
CHINA
ProdList
288
Advantage
58
Tel
+8618523575427
Email
sales@conier.com
Country
China
ProdList
49975
Advantage
58
Tel
+86-0371-86658258 +8613203830695
Fax
0086-371-86658258
Email
factory@coreychem.com
Country
China
ProdList
29798
Advantage
58
Tel
021-52961053 13524666654
Email
3004902811@qq.com
Country
China
ProdList
9724
Advantage
58
Tel
400-1647117 13681763483
Email
product02@bidepharm.com
Country
China
ProdList
59936
Advantage
58
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24961
Advantage
58
Tel
021-61734564 13854185395;
Email
info@easycdmo.com
Country
China
ProdList
10024
Advantage
58
Tel
18266960953
Email
907697096@qq.com
Country
China
ProdList
3033
Advantage
58
Tel
18143011203
Email
ET-market@chemextension.com
Country
China
ProdList
32034
Advantage
58
Tel
18024082417
Email
market@ubiochem.com
Country
China
ProdList
9835
Advantage
58
Tel
021-18017610038 18017610038
Email
897493074@qq.com
Country
China
ProdList
4995
Advantage
58
Tel
400-821-026
Email
Sales@sangon.com
Country
China
ProdList
6710
Advantage
58
Tel
025-58851090 13408877820
Email
2850281427@qq.com
Country
China
ProdList
10000
Advantage
58
Tel
51288865780
Email
sales@biosynth.com
Country
China
ProdList
6051
Advantage
58
Tel
400-025-6535
Email
sales@adooq.cn
Country
China
ProdList
6215
Advantage
58
Tel
18033875090
Email
yc-eliu@yaochengph.com
Country
China
ProdList
5488
Advantage
58
Tel
18017610038
Email
zheyansh@163.com
Country
CHINA
ProdList
3619
Advantage
58
Tel
+86-0371-88006763; +8615988602810
Email
sales@anbuchem.com
Country
China
ProdList
3002
Advantage
58
Tel
+86-057181025280; +8617767106207
Fax
0571-85806285
Email
sales@molcore.com
Country
China
ProdList
49734
Advantage
58
Tel
--
Fax
--
Email
chenjw@absin.cn
Country
CHINA
ProdList
6208
Advantage
58
Tel
--
Fax
--
Email
Proteintech-CN@ptglab.com
Country
CHINA
ProdList
6290
Advantage
58
Tel
--
Fax
--
Email
2090855807@qq.com
Country
CHINA
ProdList
6249
Advantage
58
Tel
--
Fax
--
Country
CHINA
ProdList
6969
Advantage
58
Tel
--
Fax
--
Email
yanjinbio@163.com
Country
CHINA
ProdList
6896
Advantage
58
Tel
--
Fax
--
Email
market@xlswkj.com
Country
CHINA
ProdList
6793
Advantage
58
Tel
--
Fax
--
Email
shzeysw@163.com
Country
CHINA
ProdList
6548
Advantage
58
Tel
--
Fax
--
Email
15800446246@163.com
Country
CHINA
ProdList
5416
Advantage
58
Tel
--
Fax
--
Email
john.st@163.com
Country
CHINA
ProdList
2160
Advantage
58
Tel
--
Fax
--
Email
shhebio@126.com
Country
CHINA
ProdList
6137
Advantage
58
Tel
--
Fax
--
Email
shlmai@163.com
Country
CHINA
ProdList
6055
Advantage
58
More
Less

View Lastest Price from ST1481 manufacturers

Career Henan Chemical Co
Product
ST1481 292618-32-7
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
200kg
Release date
2020-01-08

292618-32-7, ST1481Related Search:

N-[(tert-Butoxy)carbonyl]-D-tryptophan 4-QUINOLINE-OXIME ST1481

  • CPT 184
  • LBQ707; ST1481; CPT 184
  • GIMATECAN
  • ST1481
  • ST1481: GIMATECAN
  • (4S)-11-((E)-((1,1-Dimethylethoxy)imino)methyl)-4-ethyl-4-hydroxy-1,12-dihydro-14H-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H)-dione
  • 1H-Pyrano(3',4':6,7)indolizino(1,2-B)quinoline-11-carboxaldehyde, 4-ethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-, 11-(o-(1,1-dimethylethyl)oxime), (C(E),4S)-
  • 7-T-Butoxyiminomethylcamptothecin
  • Lbq707
  • Unii-7kks9R192f
  • 7-[(E)-tert-butyloxyiminomethyl]-camptothecin
  • STI481
  • ST1481 ST-1481 Gimatecan
  • (S,E)-4-Ethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-11-carbaldehyde O-(tert-butyl) oxime
  • Gimatecan, 10 mM in DMSO
  • (S,E)-4-Ethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-11-carbaldehyde O-(tert-butyl) oxime
  • 292618-32-7