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Zotiraciclib diHCl (TG-02, SB-1317)

Product Name
Zotiraciclib diHCl (TG-02, SB-1317)
CAS No.
1354567-82-0
Chemical Name
Zotiraciclib diHCl (TG-02, SB-1317)
Synonyms
Zotiraciclib HCl;Zotiraciclib diHCl (TG-02, SB-1317)
CBNumber
CB010234389
Molecular Formula
C23H25ClN4O
Formula Weight
408.93
MOL File
1354567-82-0.mol
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Hazard and Precautionary Statements (GHS)

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Zotiraciclib diHCl (TG-02, SB-1317) Chemical Properties,Usage,Production

Description

Zotiraciclib, also known as TG02 and SB1317, is a novel small molecule potent CDK/JAK2/FLT3 inhibitor. Zotiraciclib may be useful for the treatment of cancer that crosses the blood brain barrier and acts by depleting Myc through the inhibition of cyclin-dependent kinase 9 (CDK9). It is one of a number of CDK inhibitors under investigation; others targeting CDK9 for the treatment of acute myeloid leukemia include alvocidib and atuveciclib. Myc overexpression is a known factor in many cancers, with 80 percent of glioblastomas characterized by this property.

Zotiraciclib diHCl (TG-02, SB-1317) Preparation Products And Raw materials

Raw materials

Preparation Products

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