ChemicalBook > CAS DataBase List > Zotiraciclib diHCl (TG-02, SB-1317)
Zotiraciclib diHCl (TG-02, SB-1317)
- Product Name
- Zotiraciclib diHCl (TG-02, SB-1317)
- CAS No.
- 1354567-82-0
- Chemical Name
- Zotiraciclib diHCl (TG-02, SB-1317)
- Synonyms
- Zotiraciclib HCl;Zotiraciclib diHCl (TG-02, SB-1317)
- CBNumber
- CB010234389
- Molecular Formula
- C23H25ClN4O
- Formula Weight
- 408.93
- MOL File
- 1354567-82-0.mol
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Zotiraciclib diHCl (TG-02, SB-1317) Chemical Properties,Usage,Production
Description
Zotiraciclib, also known as TG02 and SB1317, is a novel small molecule potent CDK/JAK2/FLT3 inhibitor. Zotiraciclib may be useful for the treatment of cancer that crosses the blood brain barrier and acts by depleting Myc through the inhibition of cyclin-dependent kinase 9 (CDK9). It is one of a number of CDK inhibitors under investigation; others targeting CDK9 for the treatment of acute myeloid leukemia include alvocidib and atuveciclib. Myc overexpression is a known factor in many cancers, with 80 percent of glioblastomas characterized by this property.
Zotiraciclib diHCl (TG-02, SB-1317) Preparation Products And Raw materials
Raw materials
Preparation Products
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