ChemicalBook > CAS DataBase List > Cyclohexanecarboxamide, N-[2-[(ethylsulfonyl)amino]-5-(trifluoromethyl)-3-pyridinyl]-, sodium salt, hydrate (1:1:1)
Cyclohexanecarboxamide, N-[2-[(ethylsulfonyl)amino]-5-(trifluoromethyl)-3-pyridinyl]-, sodium salt, hydrate (1:1:1)
- Product Name
- Cyclohexanecarboxamide, N-[2-[(ethylsulfonyl)amino]-5-(trifluoromethyl)-3-pyridinyl]-, sodium salt, hydrate (1:1:1)
- CAS No.
- 351999-87-6
- Chemical Name
- Cyclohexanecarboxamide, N-[2-[(ethylsulfonyl)amino]-5-(trifluoromethyl)-3-pyridinyl]-, sodium salt, hydrate (1:1:1)
- Synonyms
- Fuzapladib sodium;IS-741 sodium monohydrate;{3-[(Cyclohexylcarbonyl)amino]-5-(trifluorométhyl)-2-pyridinyl}(éthylsulfonyl)azanide de sodium, hydrate (1:1:1);Cyclohexanecarboxamide, N-[2-[(ethylsulfonyl)amino]-5-(trifluoromethyl)-3-pyridinyl]-, sodium salt, hydrate (1:1:1)
- CBNumber
- CB010340929
- Molecular Formula
- C15H23F3N3NaO4S
- Formula Weight
- 421.41
- MOL File
- 351999-87-6.mol
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Cyclohexanecarboxamide, N-[2-[(ethylsulfonyl)amino]-5-(trifluoromethyl)-3-pyridinyl]-, sodium salt, hydrate (1:1:1) Property
- InChI
- InChI=1S/C15H20F3N3O3S.Na.H2O.H/c1-2-25(23,24)21-13-12(8-11(9-19-13)15(16,17)18)20-14(22)10-6-4-3-5-7-10;;;/h8-10H,2-7H2,1H3,(H,19,21)(H,20,22);;1H2;
- InChIKey
- QGYVDECYMSBHMK-UHFFFAOYSA-N
- SMILES
- N(C1C=C(C(F)(F)F)C=NC=1NS(=O)(=O)CC)C(C1CCCCC1)=O.[NaH].O
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Cyclohexanecarboxamide, N-[2-[(ethylsulfonyl)amino]-5-(trifluoromethyl)-3-pyridinyl]-, sodium salt, hydrate (1:1:1) Chemical Properties,Usage,Production
Description
Fuzapladib sodium hydrate, also known as N-[2-(Sodioethanesulfonamido)-5-(trifluoromethyl)pyridin-3-yl]cyclohexanecarboxamide monohydrate, is a phospholipase A2 ( PLA2) inhibitor and a leukocyte function-associated antigen-1 (LFA-1) activation inhibitor for the treatment of acute pancreatitis (AP) in animal species (dogs).
Uses
Fuzapladib Sodium Hydrate is a synthetic anti-inflammatory agent that shows inhibitory effect on cytosolic phospholipase A2 (cPLA2).
Mechanism of action
Fuzapladib sodium hydrate controls the progression of pancreatitis by blocking the activation of adhesion molecules (integrins) expressed on the surface of inflammatory cells and preventing inflammatory cells from adhering to vascular endothelial cells and infiltrating tissues.
Cyclohexanecarboxamide, N-[2-[(ethylsulfonyl)amino]-5-(trifluoromethyl)-3-pyridinyl]-, sodium salt, hydrate (1:1:1) Preparation Products And Raw materials
Raw materials
Preparation Products
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Cyclohexanecarboxamide, N-[2-[(ethylsulfonyl)amino]-5-(trifluoromethyl)-3-pyridinyl]-, sodium salt, hydrate (1:1:1) Suppliers
- Tel
- +8613564774135
- zijue.cai@tsbiochem.com
- Country
- United States
- ProdList
- 19885
- Advantage
- 58
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View Lastest Price from Cyclohexanecarboxamide, N-[2-[(ethylsulfonyl)amino]-5-(trifluoromethyl)-3-pyridinyl]-, sodium salt, hydrate (1:1:1) manufacturers
Hpets Biotech Company (Chongqing) Co.,ltd
- Product
- Fuzapladib sodium 351999-87-6
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100 tons
- Release date
- 2023-03-21