ChemicalBook > CAS DataBase List > 3-Fluoro-4-methoxyphenylacetic acid

3-Fluoro-4-methoxyphenylacetic acid

Product Name
3-Fluoro-4-methoxyphenylacetic acid
CAS No.
452-14-2
Chemical Name
3-Fluoro-4-methoxyphenylacetic acid
Synonyms
RARECHEM AL BO 1534;3F-4-METHOXYPHENYLESSIGSRE 5 G;4-(Carboxymethyl)-2-fluoroanisole;3-FLUORO-4-METHOXYPHENYLACETIC ACID;3-Fluoro-4-methyloxyphenylaceticacid;3-Fluoro-4-methoxyphenylaceticacid98%;Benzeneacetic acid, 3-fluoro-4-methoxy-;2-(3-fluoro-4-methoxyphenyl)acetic acid;3-Fluoro-4-methoxyphenylacetic acid 98%;4-(3-Fluoro-4-Methyloxyphenylacetic acid
CBNumber
CB0104052
Molecular Formula
C9H9FO3
Formula Weight
184.16
MOL File
452-14-2.mol
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3-Fluoro-4-methoxyphenylacetic acid Property

Melting point:
111-113°C
Boiling point:
309.0±27.0 °C(Predicted)
Density 
1.269±0.06 g/cm3(Predicted)
storage temp. 
Store below +30°C.
pka
4.25±0.10(Predicted)
form 
powder
color 
White to off-white
CAS DataBase Reference
452-14-2(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
HazardClass 
IRRITANT
HS Code 
2918290090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.43872
Product name
3-Fluoro-4-methoxyphenylacetic acid
Purity
≥99% (HPLC)
Packaging
5G
Price
$61
Updated
2025/07/31
Sigma-Aldrich
Product number
8.43872
Product name
3-Fluoro-4-methoxyphenylacetic acid
Purity
≥99% (HPLC)
Packaging
10g
Price
$149
Updated
2023/01/07
TRC
Product number
F599325
Product name
3-Fluoro-4-methoxyphenylacetic acid
Packaging
250mg
Price
$45
Updated
2021/12/16
AK Scientific
Product number
J98090
Product name
3-Fluoro-4-methoxyphenylacetic acid
Packaging
5g
Price
$11
Updated
2021/12/16
Apolloscientific
Product number
PC3802
Product name
3-Fluoro-4-methoxyphenylacetic acid
Purity
98%
Packaging
5g
Price
$15
Updated
2021/12/16
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3-Fluoro-4-methoxyphenylacetic acid Chemical Properties,Usage,Production

Synthesis

3-fluoro-4-methoxyphenylacetonitrile (42 g, 0.25 mol) was heated for 5 h with 32 g of potassium hydroxide solution in 120 mL of ethanol and 30 mL of water. After the distillation of ethanol, the residue was diluted with water to a volume of 175 mL. The solution was filtered over the charcoal, and the filtrate was acidified by 50 percent H2SO4. The resulting solid was filtered and dried, yielding 3-Fluoro-4-methoxyphenylacetic acid.

References

[1] Collection of Czechoslovak Chemical Communications, 1990, vol. 55, # 1, p. 296 - 306
[2] European Journal of Medicinal Chemistry, 2014, vol. 87, p. 508 - 518
[3] Monatshefte fuer Chemie, 1955, vol. 86, p. 511,515
[4] DRP/DRBP Org.Chem.,
[5] Chemische Berichte, 1952, vol. 85, p. 577,580

3-Fluoro-4-methoxyphenylacetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 3-Fluoro-4-methoxyphenylacetic acid manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
3-Fluoro-4-methoxyphenylacetic acid 452-14-2
Price
US $55.00-15.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20000KG
Release date
2024-08-05
Shaanxi Dideu Medichem Co. Ltd
Product
2-(3-Fluoro-4-Methoxyphenyl)acetic acid 452-14-2
Price
US $1.00-1.60/KG
Min. Order
1KG
Purity
99%+
Supply Ability
10000KG
Release date
2024-04-24
Zhuozhou Wenxi import and Export Co., Ltd
Product
3-FLUORO-4-METHOXYPHENYLACETIC ACID 452-14-2
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-10

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