N-(6-Bromoimidazo[1,2-a]pyridin-2-yl)cyclopropanecarboxamide

Product Name: N-(6-Bromoimidazo[1,2-a]pyridin-2-yl)cyclopropanecarboxamide
CAS No.: 1808928-00-8
Chemical Name: N-(6-Bromoimidazo[1,2-a]pyridin-2-yl)cyclopropanecarboxamide
Synonyms: N-(6-Bromoimidazo[1,2-a]pyridin-2-yl)cyclopropanecarboxamide;Cyclopropanecarboxamide, N-(6-bromoimidazo[1,2-a]pyridin-2-yl)-
CBNumber: CB010718311
Molecular Formula: C11H10BrN3O
Formula Weight: 280.12
MOL File: 1808928-00-8.mol

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N-(6-Bromoimidazo[1,2-a]pyridin-2-yl)cyclopropanecarboxamide Property

Density: 1.81±0.1 g/cm3(Predicted)
pka: 9.83±0.20(Predicted)
InChI: InChI=1S/C11H10BrN3O/c12-8-3-4-10-13-9(6-15(10)5-8)14-11(16)7-1-2-7/h3-7H,1-2H2,(H,14,16)
InChIKey: LAKCXXIEOGRDJQ-UHFFFAOYSA-N
SMILES: C1(C(NC2=CN3C(=N2)C=CC(Br)=C3)=O)CC1

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Hazard and Precautionary Statements (GHS)

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N-(6-Bromoimidazo[1,2-a]pyridin-2-yl)cyclopropanecarboxamide Chemical Properties,Usage,Production

Synthesis

To a solution of 6-Bromoimidazo[1,2-a]pyridin-2-amine (73 g, 346 mmol) in CH2Cl2 (1.5 L) was added Et3N (42 g, 415 mmol). Cyclopropanecarbonyl chloride (41 g, 398 mmol) in CH2Cl2 (100 mL) was added dropwise at 0 C. After the addition was complete, the mixture was warmed to room temperature and stirred for 3 h. After the reaction was complete according to TLC, saturated K2CO3 solution (100 mL) was added to quench the reaction. The mixture was stirred for 2h. Yellow solids crushed out of the mixture were collected by filtration and dried to provide N-(6-Bromoimidazo[1,2-a]pyridin-2-yl)cyclopropanecarboxamide as a yellow solid (97 g, 99%)

N-(6-Bromoimidazo[1,2-a]pyridin-2-yl)cyclopropanecarboxamide Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from N-(6-Bromoimidazo[1,2-a]pyridin-2-yl)cyclopropanecarboxamide manufacturers

Huida Pharmaceutical Technology (Shanghai) Co., Ltd.

Product: N-(6-Bromoimidazo[1,2-a]pyridin-2-yl)cyclopropanecarboxamide 1808928-00-8
Price: US $0.00-0.00/kg
Min. Order: 0.1kg
Purity: 98%
Supply Ability: 100kg
Release date: 2023-03-08

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1808928-00-8