4(1H)-Pyrimidinethione (9CI)
- Product Name
- 4(1H)-Pyrimidinethione (9CI)
- CAS No.
- 1450-86-8
- Chemical Name
- 4(1H)-Pyrimidinethione (9CI)
- Synonyms
- PyriMidine-4-thiol;4-mercaptopyrimidine;4(3H)-Pyrimidinethione;4(1H)-Pyrimidinethione;4(1H)-Pyrimidinethione (9CI);1,4-dihydropyrimidine-4-thione;4(1H)-Pyrimidinethione (9CI) ISO 9001：2015 REACH
- CBNumber
- CB01081536
- Molecular Formula
- C4H4N2S
- Formula Weight
- 112.15
- MOL File
- 1450-86-8.mol
4(1H)-Pyrimidinethione (9CI) Property
- Melting point:
- 190-192 °C(Solv: water (7732-18-5))
- Boiling point:
- 191.3±23.0 °C(Predicted)
- Density
- 1.30±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 6.90±0.10(Predicted)
- Appearance
- Brown to reddish brown Solid
N-Bromosuccinimide Price
- Product number
- D454030
- Product name
- 1,4-dihydropyrimidine-4-thione
- Packaging
- 250mg
- Price
- $350
- Updated
- 2021/12/16
- Product number
- 1085CM
- Product name
- 4-Pyrimidinethiol
- Packaging
- 1g
- Price
- $292
- Updated
- 2021/12/16
- Product number
- UT02401
- Product name
- Pyrimidine-4(1H)-thione
- Purity
- 97%
- Packaging
- 0.5g
- Price
- $160.35
- Updated
- 2021/12/16
- Product number
- CM128175
- Product name
- pyrimidine-4(3H)-thione
- Purity
- 95%
- Packaging
- 1g
- Price
- $196
- Updated
- 2021/12/16
- Product number
- UT02401
- Product name
- Pyrimidine-4(1H)-thione
- Purity
- 97%
- Packaging
- 1g
- Price
- $253.18
- Updated
- 2021/12/16
4(1H)-Pyrimidinethione (9CI) Chemical Properties,Usage,Production
Synthesis
51953-17-4
1450-86-8
The general procedure for the synthesis of pyrimidine-4(3H)-thione from pyrimidin-4(1H)-one is as follows: Step a: Preparation of 4-mercaptopyrimidine 4-Hydroxypyrimidine (1 g) and diphosphorus pentasulfide (2.32 g) were dissolved in 15 ml of pyridine, stirred and heated to reflux. After refluxing the reaction mixture for 3 hours, it was cooled to room temperature and 30 ml of water was added. Subsequently, the reaction mixture was concentrated under reduced pressure. The concentrated mixture was extracted with ethyl acetate (3 x 30 ml), the organic phases were combined, washed with water, dried over anhydrous MgSO4, filtered and the solvent was evaporated under reduced pressure to give the yellow solid product 4-mercapto-pyrimidine (0.42 g, 36% yield). The product did not need further purification and could be used directly in the subsequent reaction.
References
[1] Patent: US5250536, 1993, A
4(1H)-Pyrimidinethione (9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
View Lastest Price from 4(1H)-Pyrimidinethione (9CI) manufacturers
- Product
- 4(1H)-Pyrimidinethione (9CI) 1450-86-8
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.0% min
- Supply Ability
- 100 tons min
- Release date
- 2021-05-25