5'-Amino-2'-hydroxyacetophenone
- Product Name
- 5'-Amino-2'-hydroxyacetophenone
- CAS No.
- 50-80-6
- Chemical Name
- 5'-Amino-2'-hydroxyacetophenone
- Synonyms
- 1-(5-Amino-2-hydroxyphenyl);5'-Amino-2'-hydroxyacetophenone;Ethanone, 1-(5-amino-2-hydroxyphenyl)-;5''-AMINO-2''-HYDROXYACETOPHENONE {1-(5-AMINO-2-HYDROXYPHENYL)ETHANONE}
- CBNumber
- CB01103353
- Molecular Formula
- C8H9NO2
- Formula Weight
- 151.16
- MOL File
- 50-80-6.mol
5'-Amino-2'-hydroxyacetophenone Property
- Melting point:
- 121–122°C
- Boiling point:
- 335.4±27.0 °C(Predicted)
- Density
- 1.242±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 10.42±0.18(Predicted)
- Appearance
- Light yellow to yellow Solid
Safety
- HS Code
- 2914500090
N-Bromosuccinimide Price
- Product number
- A611475
- Product name
- 1-(5-Amino-2-hydroxyphenyl)ethanone
- Packaging
- 50mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- A611475
- Product name
- 1-(5-Amino-2-hydroxyphenyl)ethanone
- Packaging
- 1g
- Price
- $545
- Updated
- 2021/12/16
- Product number
- 7032AB
- Product name
- 1-(5-Amino-2-hydroxyphenyl)ethanone
- Packaging
- 10g
- Price
- $1137
- Updated
- 2021/12/16
- Product number
- FA70776
- Product name
- 5-Amino-2-hydroxyacetophenone
- Packaging
- 250mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- FA70776
- Product name
- 5-Amino-2-hydroxyacetophenone
- Packaging
- 500mg
- Price
- $100
- Updated
- 2021/12/16
5'-Amino-2'-hydroxyacetophenone Chemical Properties,Usage,Production
Uses
1-(5-Amino-2-hydroxyphenyl)ethanone is used in the preparation of alkylated flavonoid compounds for use as therapeutic antioxidants. It is also used to synthesize spiro[chromanone-piperidine]s as acetyl-CoA carboxylase inhibitors.
Preparation
Also obtained by refluxing a suspension of N-(3-acetyl-4- hydroxyphenyl)acetamide in 15% hydrochloric acid for 40 min (84%).
Synthesis
7298-67-1
50-80-6
The hydrolysis reaction was carried out by refluxing 2-hydroxy-5-acetamidoacetophenone in 2N hydrochloric acid solution for 6 hours to obtain 5-amino-2-hydroxyacetophenone in 94% yield.
References
[1] Journal of Medicinal Chemistry, 1992, vol. 35, # 21, p. 3973 - 3976
[2] Patent: US2007/117823, 2007, A1. Location in patent: Page/Page column 8
[3] Patent: WO2007/54580, 2007, A1. Location in patent: Page/Page column 16
[4] European Journal of Medicinal Chemistry, 1991, vol. 26, # 9, p. 843 - 851
[5] Bioorganic and Medicinal Chemistry, 2004, vol. 12, # 9, p. 2079 - 2098
5'-Amino-2'-hydroxyacetophenone Preparation Products And Raw materials
Raw materials
Preparation Products
5'-Amino-2'-hydroxyacetophenone Suppliers
- Tel
- +1-2266000236
- sales@rdscientific.com
- Country
- Canada
- ProdList
- 1914
- Advantage
- 58
View Lastest Price from 5'-Amino-2'-hydroxyacetophenone manufacturers
- Product
- 5'-Amino-2'-hydroxyacetophenone 50-80-6
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 85.0-99.8%
- Supply Ability
- 20tons
- Release date
- 2020-10-28