SMZ/TMP

Product Name: SMZ/TMP
CAS No.: 8064-90-2
Chemical Name: SMZ/TMP
Synonyms: TMP-SMX;SMZ/TMP;Septrim;Chemitrim;Trimforte;Trimethoprimsulfa;Co-Trimoxazole (CTX), 95%;Trimethoprim-Sulfamethoxazole;Sulfamethoxazole/Trimethoprim;TRIMETHOPRIM/SULPHAMETHOXAZOLE
CBNumber: CB01105579
Molecular Formula: C24H29N7O6S
Formula Weight: 543.6
MOL File: 8064-90-2.mol

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SMZ/TMP Property

storage temp.: -20°C
solubility: DMF: 10mg/mL,DMSO: 10mg/mL,DMSO:PBS (pH 7.2) (1:4): 0.2mg/mL,Ethanol: 0.3mg/mL
form: liquid
color: colorless to faint yellow
BCS Class: 4/4
EPA Substance Registry System: Benzenesulfonamide, 4-amino-N-(5-methyl-3-isoxazolyl)-, mixt. with 5-[(3,4,5-trimethoxyphenyl)methyl]-2,4-pyrimidinediamine (8064-90-2)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38-43
Safety Statements: 26-36/37
WGK Germany: 3
RTECS: UV8240000
Hazardous Substances Data: 8064-90-2(Hazardous Substances Data)
Toxicity: LD50 orally in mice: 5513 mg/kg (Yamamoto)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: A2487
Product name: Cotrimoxazole, Ready Made Solution
Packaging: 1ml
Price: $619
Updated: 2024/03/01

TRC

Product number: C725300
Product name: Cotrimoxazole
Packaging: 2.5g
Price: $185
Updated: 2021/12/16

TRC

Product number: C725300
Product name: Cotrimoxazole
Packaging: 10g
Price: $520
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0004695
Product name: CO-TRIMOXAZOLE
Purity: 95.00%
Packaging: 5MG
Price: $550
Updated: 2021/12/16

AK Scientific

Product number: 1199CC
Product name: Sulfamethoxazoleandtrimethoprim
Packaging: 5g
Price: $761
Updated: 2021/12/16

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SMZ/TMP Chemical Properties,Usage,Production

Uses

Cotrimoxazole is an antibiotic. Pseudomonas aeruginosa has a drug resistant rate of 66% in the years 2010-2013.

World Health Organization (WHO)

The combination of sulfamethoxazole and trimethoprim (5:1) was introduced in 1971 for the treatment of a wide variety of bacterial infections. Its use has been associated with severe sensitivity reactions, many of which have been attributed to the sulphonamide component. Elderly people seem to be more vulnerable. The World Health Organization has no information further to the above concerning restrictive action taken on this combination.

Side effects

Trimethoprim/sulfamethoxazole on a daily basis has a rapid onset of action but has rare associated side effects of bone marrow suppression and toxic epidermal necrolysis (TEN).
Nausea, vomiting, and anorexia are generally dose related. Hypersensitivity reactions (including Stevens-Johnson syndrome and hematologic reactions) occur in <5% of patients.

Dosage forms

One to two tablets a day. Trimethoprim is dosed at 200 mg/24 hours given either q.d. or b.i.d.

SMZ/TMP Preparation Products And Raw materials

Raw materials

Preparation Products

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SMZ/TMP Suppliers

China 8 India 3 United States 6 Global 17

Alfa Chemistry

Tel: 1-516-6625404
Fax: 1-516-927-0118
Email: support@alfa-chemistry.com
Country: United States
ProdList: 9171
Advantage: 60

BOC Sciences

Tel: 16314854226; +16314854226
Email: inquiry@bocsci.com
Country: United States
ProdList: 19741
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32080
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11217
Advantage: 58

Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Country: China
ProdList: 11974
Advantage: 58

Shandong Mopai Biotechnology Co., Ltd

Tel: 13070690626
Email: admin@mopaikeji.com
Country: China
ProdList: 10756
Advantage: 58

Shaanxi Istare Biotechnology Co., Ltd.

Tel: 18682931470
Email: 2142355700@qq.com
Country: China
ProdList: 4227
Advantage: 58

TargetMol Chemicals Inc.

Tel: 15002134094
Email: marketing@targetmol.cn
Country: China
ProdList: 19711
Advantage: 58

Tel: 4008-099-669
Email: 23419001name@qq.com
Country: CHINA
ProdList: 68144
Advantage: 58

TargetMol Chemicals Inc.

Tel: +8613564774135
Email: zijue.cai@tsbiochem.com
Country: United States
ProdList: 19863
Advantage: 58

8064-90-2, SMZ/TMPRelated Search:

Trimethoprim Ampicillin Cefepime Sulfamethoxazole Sulfamethoxazole/Trimethoprim Trimethoprim-Sulfamethoxazole

SMZ/TMP

Sulfamethoxazole/Trimethoprim

Trimethoprim-Sulfamethoxazole Combination

TRIMETHOPRIM/SULPHAMETHOXAZOLE

Chemitrim

Septrim

Cotrimoxazole, Ready Made Solution

TMP-SMX

Trimethoprim-Sulfamethoxazole

Co-Trimoxazole (CTX), 95%

Trimethoprimsulfa

Trimforte

5-[(3,4,5-trimethoxyphenyl)methyl]-2,4-pyrimidinediamine mixture with 4-amino-N-(5-methyl-3-isoxazolyl)-benzenesulfonamide

8064-90-2