ChemicalBook > CAS DataBase List > 4,6-Dihydroxy-2-phenylpyrimidine

4,6-Dihydroxy-2-phenylpyrimidine

Product Name
4,6-Dihydroxy-2-phenylpyrimidine
CAS No.
13566-71-7
Chemical Name
4,6-Dihydroxy-2-phenylpyrimidine
Synonyms
2-Phenyl-4,6-pyrimidinediol;6-Hydroxy-2-phenyl-4(1H)-pyrimidinone;4-hydroxy-2-phenyl-1H-pyrimidin-6-one;4(3H)-Pyrimidinone, 6-hydroxy-2-phenyl-
CBNumber
CB01106354
Molecular Formula
C10H8N2O2
Formula Weight
188.18
MOL File
13566-71-7.mol
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4,6-Dihydroxy-2-phenylpyrimidine Property

Melting point:
325-330 °C
Density 
1.33±0.1 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
pka
5.04±0.10(Predicted)
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Safety

HS Code 
2933599590
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
P399943
Product name
2-Phenyl-pyrimidine-4,6-diol
Packaging
10mg
Price
$45
Updated
2021/12/16
AK Scientific
Product number
5034CB
Product name
2-Phenylpyrimidine-4,6-diol
Packaging
250mg
Price
$72
Updated
2021/12/16
AK Scientific
Product number
5034CB
Product name
2-Phenylpyrimidine-4,6-diol
Packaging
5g
Price
$143
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0021776
Product name
2-PHENYL-4,6-PYRIMIDINEDIOL
Purity
95.00%
Packaging
1G
Price
$722.8
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0021776
Product name
2-PHENYL-4,6-PYRIMIDINEDIOL
Purity
95.00%
Packaging
5G
Price
$1115.96
Updated
2021/12/16
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4,6-Dihydroxy-2-phenylpyrimidine Chemical Properties,Usage,Production

Synthesis

1670-14-0

108-59-8

13566-71-7

Benzamidine hydrochloride (26.0 g, 0.166 mol) and dimethyl malonate (21.9 g, 0.166 mol) were dissolved in anhydrous methanol (200 mL). A methanolic solution of 30% sodium methanol (89.7 g, 0.498 mol) was slowly added under stirring conditions and sodium chloride precipitation was observed to be generated during the reaction. The reaction mixture was stirred continuously at 55°C for 2 hours. After completion of the reaction, the reaction mixture was diluted with water (500 mL) to obtain a clarified solution. Subsequently, it was acidified by dropwise addition of acetic acid (35 mL) and a white precipitate was rapidly precipitated. After continued stirring for 30 min, the solid product was collected by filtration. The filter cake was washed sequentially with water, methanol and acetone and dried to give 2-phenylpyrimidine-4,6-diol in a yield of 25 g (80% yield) as a white solid.

References

[1] Patent: WO2012/167053, 2012, A1. Location in patent: Page/Page column 92

4,6-Dihydroxy-2-phenylpyrimidine Preparation Products And Raw materials

Raw materials

Preparation Products

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4,6-Dihydroxy-2-phenylpyrimidine Suppliers

Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Beijing HwrkChemical Technology Co., Ltd
Tel
18515581800 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
9400
Advantage
55
Spectrum Chemical Manufacturing Corp.
Tel
021-021-021-67601398-809-809-809 15221380277
Fax
021-57711696
Email
marketing_china@spectrumchemical.com
Country
China
ProdList
9658
Advantage
60
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9510
Advantage
58
SynAsst Chemical.
Tel
021-60343070
Fax
021-35122006
Country
China
ProdList
12740
Advantage
55
Shanghai KaiYuLin pharmaceutical technology co., LTD
Tel
021-18721936-595 18721936595
Fax
-
Email
shkylpharma@126.com
Country
China
ProdList
734
Advantage
55
Zhengzhou Acme Chemical Co., Ltd.
Tel
0371-0371-55629727 13323845623
Fax
037155629727
Email
2885676761@qq.com
Country
China
ProdList
10110
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Aikon International Limited
Tel
025-58859352 18068836627
Fax
(5)02557626880
Email
dt3@aikonchem.com
Country
China
ProdList
15493
Advantage
58
Henan Aosman Biotechnology Co., LTD
Tel
0371-0371-61318675 17719817155
Fax
0371-61318675
Email
sales@xlinebio.com
Country
China
ProdList
2857
Advantage
58
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View Lastest Price from 4,6-Dihydroxy-2-phenylpyrimidine manufacturers

Shanghai Rlavie Technology Co ltd
Product
4,6-Dihydroxy-2-phenylpyrimidine 13566-71-7
Price
US $0.00-0.00/KG
Min. Order
1g
Purity
98%min
Supply Ability
100kgs/month
Release date
2021-11-20
Career Henan Chemical Co
Product
4,6-Dihydroxy-2-phenylpyrimidine 13566-71-7
Price
US $0.01/KG
Min. Order
1KG
Purity
98%; 99%
Supply Ability
500g;1kg; 25kg
Release date
2020-01-10