Mannomustine

Product Name: Mannomustine
CAS No.: 551-74-6
Chemical Name: Mannomustine
Synonyms: NSC9698;Degranol;NSC 9698;NSC-9698;Degranol chinoin;MANNOMUSTINEHYDROCHLORIDE;MANNOUMUSINEDIHYDROCHLORIDE;Mannomustine dihydrochloride;1,6-Bis[(chloroethyl)amino]-1,6-dideoxy-D-mannite dihydrochloride;1,6-Bis[(chloroethyl)amino]-1,6-desoxy-D-mannitol dihydrochloride
CBNumber: CB01179093
Molecular Formula: C10H22Cl2N2O4.2ClH
Formula Weight: 378.122
MOL File: 551-74-6.mol

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Mannomustine Property

Melting point:: 240-242 °C
alpha: D20 +18.46° (c = 1.81 in H2O)
CAS DataBase Reference: 551-74-6
IARC: 3 (Vol. 9, Sup 7) 1987
EPA Substance Registry System: Degranol (551-74-6)

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Safety

Toxicity: LD50 i.v. in rats: 56 mg/kg (Scherf)

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Hazard and Precautionary Statements (GHS)

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Mannomustine Chemical Properties,Usage,Production

Uses

Mannomustine dihydrochloride is an alkylating agent with antineoplastic activity. Mannomustine dihydrochloride causes severe bone marrow depression. Mannomustine dihydrochloride is a powerful vesicant.

Definition

ChEBI: Mannomustine dihydrochloride is an organic molecular entity.

Safety Profile

Poison by intravenous, subcutaneous, and parented routes. Experimental reproductive effects. Questionable carcinogen with experimental carcinogenic and neoplastigenic data. Human mutation data reported. A drug used for the treatment of malignant neoplasms. When heated to decomposition it emits very toxic fumes of HCl and NOx. See also MANNOMUSTINE.

References

[1] Some effects of 1-methyl-2-p-(isopropyl-carbamoyl)-benzyl-hydrazine and mannomustine on the metabolism of human erythrocytes in vitro

Mannomustine Preparation Products And Raw materials

Raw materials

Preparation Products

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Mannomustine Suppliers

China 3 United States 3 Global 6

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32470
Advantage: 58

TargetMol Chemicals Inc.

Tel: 15002134094
Email: marketing@targetmol.cn
Country: China
ProdList: 29391
Advantage: 58

TargetMol Chemicals Inc.

Tel: +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 19964
Advantage: 58

551-74-6, MannomustineRelated Search:

mannomustine Mannomustine

MANNOMUSTINEHYDROCHLORIDE

MANNOUMUSINEDIHYDROCHLORIDE

Mannomustine dihydrochloride

1,6-Bis-(.beta.-chloraethylamino)-1,6-desoxy-D-mannit-dichlorhydrat

1,6-Bis[(chloroethyl)amino]-1,6-desoxy-D-mannitol dihydrochloride

1,6-Bis[(chloroethyl)amino]-1,6-dideoxy-D-mannite dihydrochloride

1,6-Dideoxy-1,6-di[(2-chloroethyl)amino]-D-mannitol dihydrochloride

Degranol

Degranol chinoin

D-Mannitol, 1,6-bis(2-chloroethylamino)-1,6-dideoxy-, dihydrochloride

D-Mannitol, 1,6-bis[(2-chloroethyl)amino]-1,6-dideoxy-, dihydrochloride

NSC 9698

NSC9698

NSC-9698

551-74-6

C10H24Cl4N2O4