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Pramiverine

Product Name
Pramiverine
CAS No.
14334-40-8
Chemical Name
Pramiverine
Synonyms
Pramiverin;4,4-Diphenyl-N-isopropylcyclohexanamine;N-isopropyl-4,4-diphenylcyclohexanamine;4,4-diphenyl-N-propan-2-ylcyclohexan-1-amine;Cyclohexanamine, N-(1-methylethyl)-4,4-diphenyl-
CBNumber
CB01179558
Molecular Formula
C21H27N
Formula Weight
293.45
MOL File
14334-40-8.mol
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Pramiverine Property

Melting point:
70° (Enenkel)
Boiling point:
bp0.05 164-165°
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0025858
Product name
PRAMIVERINE
Purity
95.00%
Packaging
5MG
Price
$496.03
Updated
2021/12/16
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Pramiverine Chemical Properties,Usage,Production

Originator

Sistalgin, Bracco, Italy,1974

Definition

ChEBI: Pramiverine is a diarylmethane.

Manufacturing Process

20 g 4,4-diphenyl-cyclohexen-(2)-one, 10 g isopropylamine, and 50 ml tetrahydrofuran are agitated for 10 hours in a bomb tube at 200°C. Subsequently, the reaction mixture is cooled, and the tetrahydrofuran and theexcess isopropylamine are distilled off. The remaining Schiff base is dissolved in methanol and after the addition of 2 g platinum oxide, the base is hydrogenated at normal pressure and room temperature until a quantity of hydrogen corresponding to 2 mols has been absorbed.
The mixture is filtered off from the catalyst, made acidic with dilute hydrochloric acid, and the methanol is removed under vacuum. The remaining aqueous solution is made alkaline with solution of sodium hydroxide and extracted with ether. After drying and concentrating the ether extract, there is obtained 17 g 1-isopropylamino-4,4-diphenyl-cyclohexane, boiling point 164°C to 165°C/0.05 mm. The hydrochloride melts at 230°C.

Therapeutic Function

Spasmolytic

Pramiverine Preparation Products And Raw materials

Raw materials

Preparation Products

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Pramiverine Suppliers

TargetMol Chemicals Inc.
Tel
15002134094
Email
marketing@targetmol.cn
Country
China
ProdList
19704
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58
TargetMol Chemicals Inc.
Tel
+8613564774135
Email
zijue.cai@tsbiochem.com
Country
United States
ProdList
19885
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38631
Advantage
58

14334-40-8, PramiverineRelated Search:


  • 4,4-Diphenyl-N-isopropylcyclohexanamine
  • Pramiverin
  • N-isopropyl-4,4-diphenylcyclohexanamine
  • 4,4-diphenyl-N-propan-2-ylcyclohexan-1-amine
  • Cyclohexanamine, N-(1-methylethyl)-4,4-diphenyl-
  • 14334-40-8