Zylofuramine

Product Name: Zylofuramine
CAS No.: 3563-92-6
Chemical Name: Zylofuramine
Synonyms: Zylofuramine;(1R)-N-ethyl-1-[(2R)-oxolan-2-yl]-2-phenylethanamine;(1R)-N-ethyl-1-[(2R)-oxolan-2-yl]-2-phenyl-ethanamine;ethyl-[(1R)-2-phenyl-1-[(2R)-tetrahydrofuran-2-yl]ethyl]amine;2-Furanmethanamine, N-ethyltetrahydro-α-(phenylmethyl)-, [R-(R*,R*)]- (9CI)
CBNumber: CB01180114
Molecular Formula: C14H21NO
Formula Weight: 219.32
MOL File: 3563-92-6.mol

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Zylofuramine Property

Boiling point:: 328.8±15.0 °C(Predicted)
Density: 1.3277 (rough estimate)
refractive index: 1.5240 (estimate)
storage temp.: Store at -20°C
solubility: DMSO: ≥ 100 mg/mL (455.95 mM)
form: Solid
pka: 9.35±0.19(Predicted)
color: White to off-white

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Safety

Toxicity: LD50 oral in mouse: 475mg/kg

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0016067
Product name: ZYLOFURAMINE
Purity: 95.00%
Packaging: 5MG
Price: $497.22
Updated: 2021/12/16

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Zylofuramine Chemical Properties,Usage,Production

Originator

Zylofuramine,ZYF Pharm Chemical

Uses

Zylofuramine is a psychomotor stimulant[1].

Manufacturing Process

A mixture of furfurylbenzyl ketone and of N-ethyl-α-benzylamine in methanol was hydrogenated over Raney nickel at 150°C and at a pressure of 1500 p.s.i. The catalyst was removed by filtration and the solvent removed by vacuum distillation. The oily residue was taken up in ether, the ether solution washed with dilute hydrochloric acid and the aqueous layer separated. Addition of 35% sodium solution caused the separation of an oil which was taken up in ether. Removal of the ether by evaporation followed by distillation of the residue gave N-ethyl-α-benzyltetrahydrofurfurylamine, boillin point 101°C/0.07 mm.

Therapeutic Function

Psycho-analeptic

References

[1] HARRIS LS, et al. ALPHA-BENZYLTETRAHYDROFURFURYLAMINES--A NEW SERIES OF PSYCHOMOTOR STIMULANTS. III. THE PHARMACOLOGY OF D-THREO ALPHA-BENZYL-N-ETHYLTETRAHYDROFURFURYLAMINE (ZYLOFURAMINE). Arch Int Pharmacodyn Ther. 1963 Dec 1;146:392-405. PMID:14099588

Zylofuramine Preparation Products And Raw materials

Raw materials

Preparation Products

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Zylofuramine Suppliers

China 16 United States 2 Global 18

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
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Country: United States
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Career Henan Chemica Co

Tel: +86-0371-86658258 +8613203830695
Fax: 0371-86658258
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Country: China
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
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Shanghai hongqu biomedical technology co. LTD

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Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
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TargetMol Chemicals Inc.

Tel: 4008200310
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Taizhou Chuanxu Pharmaceutical Technology Co., Ltd.

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Adooq Bioscience LLC

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Taizhou Zhongzhi Biotechnology Co., Ltd

Tel: 13012344321
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Country: China
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3563-92-6, ZylofuramineRelated Search:

Zylofuramine (R)-(-)-Tetrahydrofurfurylamine

(1R)-N-ethyl-1-[(2R)-oxolan-2-yl]-2-phenylethanamine

(1R)-N-ethyl-1-[(2R)-oxolan-2-yl]-2-phenyl-ethanamine

ethyl-[(1R)-2-phenyl-1-[(2R)-tetrahydrofuran-2-yl]ethyl]amine

Zylofuramine

2-Furanmethanamine, N-ethyltetrahydro-α-(phenylmethyl)-, [R-(R*,R*)]- (9CI)

3563-92-6