ChemicalBook > CAS DataBase List > Emodepside

Emodepside

Product Name
Emodepside
CAS No.
155030-63-0
Chemical Name
Emodepside
Synonyms
QHT06;Emodepside;Bay 44-4400;PF 1022-221;Emodeposide;Emodepside D8;Emodepside - Bio-X ?;Emodepside, 10 mM in DMSO;Cyclo(.alpha.R)-.alpha.-hydroxy-4-(4-morpholinyl)benzeneprop;(3S,6R,9S,12R,15S,18R,21S,24R)-3,9,15,21-tetraisobutyl-4,6,10,16,18,22-hexamethyl-12,24-bis(4-morpholinobenzyl)-1,7,13,19-tetraoxa-4,10,16,22-tetraazacyclotetracosan-2,5,8,11,14,17,20,23-octaone
CBNumber
CB01212686
Molecular Formula
C60H90N6O14
Formula Weight
1119.39
MOL File
155030-63-0.mol
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Emodepside Property

Boiling point:
1219.3±65.0 °C(Predicted)
Density 
1.104±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO : ≥ 31 mg/mL (27.69 mM)
pka
5.34±0.40(Predicted)
form 
Solid
color 
White to off-white
InChIKey
ZMQMTKVVAMWKNY-FYSVEKGBNA-N
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Safety

WGK Germany 
WGK 3
Storage Class
11 - Combustible Solids
Hazard Classifications
Acute Tox. 4 Oral
Repr. 2
STOT RE 2
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H372Causes damage to organs through prolonged or repeated exposure

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P314Get medical advice/attention if you feel unwell.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML3364
Product name
Emodepside
Purity
≥95% (HPLC)
Packaging
5MG
Price
$82.22
Updated
2025/07/31
Sigma-Aldrich
Product number
SML3364
Product name
Emodepside
Purity
≥95% (HPLC)
Packaging
25MG
Price
$386
Updated
2025/07/31
American Custom Chemicals Corporation
Product number
MTB0000956
Product name
EMODEPSIDE
Purity
95.00%
Packaging
5MG
Price
$495.87
Updated
2021/12/16
ChemScene
Product number
CS-6406
Product name
Emodepside
Purity
>98.0%
Packaging
50mg
Price
$1056
Updated
2021/12/16
ChemScene
Product number
CS-6406
Product name
Emodepside
Purity
>98.0%
Packaging
100mg
Price
$1740
Updated
2021/12/16
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Emodepside Chemical Properties,Usage,Production

Uses

Emodepside-d6 is an isotopic labeled compound of Emodepside; an anthelmintic drug very active against gastrointestinal nematodes.

Definition

ChEBI: A cyclooctadepsipeptide consisting of D-lactoyl, N-methyl-L-leucyl, 3-[4-(4-morpholinyl)phenyl]-D-lactoyl, N-methyl-L-leucyl, D-lact yl, N-methyl-L-leucyl, 3-[4-(4-morpholinyl)phenyl]-D-lactoyl, and N-methyl-L-leucyl residues joined in sequence to give a 24-membered macrocycle. An anthelmintic, it i used with praziquantel for the treatment and control of hookworm, roundworm and tapeworm infections in cats.

Biological Activity

Emodepside is a cyclooctadepsipeptide anthelmintic a novel mode of action involving the calcium-gated potassium channel SLO-1 in C. elegans, sometimes mediated by a latrophilin (LAT) receptor.

Veterinary Drugs and Treatments

Emodepside/Praziquantel topical solution (Profender?) is indicated for the treatment and control of hookworm infections caused by Ancylostoma tubaeforme (adults, immature adults, and fourth stage larvae), roundworm infections caused by Toxocara cati (adults and fourth stage larvae), and tapeworm infections caused by Dipylidium caninum (adults) and Taenia taeniaeformis (adults) in cats.

in vivo

Emodepside interferes with signaling at the neuromuscular junction on the body-wall muscles, pharynx and egg-laying muscles and thus inhibits three important physiological functions: locomotion, feeding and reproduction[4].

Emodepside Preparation Products And Raw materials

Raw materials

Preparation Products

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Emodepside Suppliers

Shanghai Mokai Pharmaceutical Technology Co., Ltd.
Tel
021-60951261 18601606476
Email
nancy@mkpharma.cn
Country
China
ProdList
453
Advantage
58
Jiangxi ravel Biotechnology Co.,Ltd
Tel
400-880-2824; 13184580281
Fax
400-880-2824
Email
hj@ruiweier.cn
Country
China
ProdList
2681
Advantage
58
Shanghai Zhibang Biological Medicine Co., LTD
Tel
021-54285032 18116461626
Fax
021-54285032
Email
25493162@qq.com
Country
China
ProdList
95
Advantage
58
Chongqing Qiantai Pharma Co., Ltd.
Tel
15862471140
Email
richardchan@bright-gene.com
Country
China
ProdList
83
Advantage
58
T&W GROUP
Tel
021-61551611 13296011611
Fax
+86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
Advantage
58
Nanjing Sunlida Biological Technology Co., Ltd.
Tel
025-57798810
Fax
025-57019371
Email
sales@sunlidabio.com
Country
China
ProdList
3239
Advantage
55
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
8000
Advantage
58
Quality Control Solutions Ltd.
Tel
66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
18364
Advantage
56
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9636
Advantage
58
BrightGene Bio-medical Technology Co., Ltd.
Tel
0512-0512-62551764 18013103761
Fax
0512-62551799
Email
sales01@bright-gene.com
Country
China
ProdList
61
Advantage
70
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View Lastest Price from Emodepside manufacturers

Wuhan JiyunZen Tech Co., Ltd.
Product
Emodepside 155030-63-0
Price
US $5.00-0.50/KG
Min. Order
1KG
Purity
99% hplc
Supply Ability
500TONS
Release date
2025-05-29
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Emodepside 155030-63-0
Price
US $0.00-0.00/Kg/Drum
Min. Order
1KG
Purity
98%min
Supply Ability
500kg
Release date
2021-10-21
Shaanxi Haibo Biotechnology Co., Ltd
Product
Emodepside 155030-63-0
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000ton
Release date
2023-09-07

155030-63-0, EmodepsideRelated Search:


  • Cyclo(.alpha.R)-.alpha.-hydroxy-4-(4-morpholinyl)benzenepropanoyl-N-methyl-L-leucyl-(2R)-2-hydroxypropanoyl-N-methyl-L-leucyl-(.alpha.R)-.alpha.-hydroxy-4-(4-morpholinyl)benzenepropanoyl-N-methyl-L-leucyl-(2R)-2-hydroxypropanoyl-N-methyl-L-leucyl
  • Emodepside
  • Cyclo(.alpha.R)-.alpha.-hydroxy-4-(4-morpholinyl)benzeneprop
  • QHT06
  • PF 1022-221
  • Bay 44-4400
  • Cyclo[(αR)-α-hydroxy-4-(4-morpholinyl)benzenepropanoyl-N-methyl-L-leucyl-(2R)-2-hydroxypropanoyl-N-methyl-L-leucyl-(αR)-α-hydroxy-4-(4-morpholinyl)benzenepropanoyl-N-methyl-L-leucyl-(2R)-2-hydroxypropanoyl-N-methyl-L-leucyl]
  • (3S,6R,9S,12R,15S,18R,21S,24R)-3,9,15,21-tetraisobutyl-4,6,10,16,18,22-hexamethyl-12,24-bis(4-morpholinobenzyl)-1,7,13,19-tetraoxa-4,10,16,22-tetraazacyclotetracosan-2,5,8,11,14,17,20,23-octaone
  • Emodepside D8
  • Cyclo(.alpha.R)-.alpha.-hydroxy-4-(4-morpholinyl)benzenepropanoyl-N-methyl-L-leucyl-(2R)-2-hydroxypropanoyl-N-methyl-L-leucyl-(.alpha.R)-.alpha.-hydroxy-4-(4-morpholinyl)benzenepropanoyl-N-methyl-L-le
  • Emodepside, 10 mM in DMSO
  • Emodepside - Bio-X ?
  • Emodeposide
  • (3S,6R,9S,12R,15S,18R,21S,24R)-3,9,15,21-Tetraisobutyl-4,6,10,16,18,22-hexamethyl-12,24-bis(4-morpholinobenzyl)-1,7,13,19-tetraoxa-4,10,16,22-tetraazacyclotetracosane-2,5,8,11,14,17,20,23-octone
  • 155030-63-0
  • C60H90N6O14
  • API