Teicoplanin A2-3

Product Name: Teicoplanin A2-3
CAS No.: 91032-36-9
Chemical Name: Teicoplanin A2-3
Synonyms: teicoplanin A2-3;Teicoplanin A2-3 DISCONTINUED. Please see T015500;34-O-[2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-[2-deoxy-2-[(1-oxodecyl)amino]-β-D-glucopyranosyl]-42-O-α-D-mannopyranosyl-ristomycinAaglycone;Ristomycin A aglycone, 34-O-[2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-[2-deoxy-2-[(1-oxodecyl)amino]-β-D-glucopyranosyl]-42-O-α-D-mannopyranosyl-;34-O-(2-(Acetylamino)-2-deoxy-beta-D-glucopyranosyl)-22,31-dichloro-7- demethyl-64-O-demethyl-19-deoxy-56-O-(2-deoxy-2-((1-oxodecyl)amino)-be ta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosylristomycin A aglycone;Ristomycin A aglycone, 34-O-2-(acetylamino)-2-deoxy-.beta.-D-glucopyranosyl-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-2-deoxy-2-(1-oxodecyl)amino-.beta.-D-glucopyranosyl-42-O-.alpha.-D-mannopyranosyl-
CBNumber: CB01215182
Molecular Formula: C88H97Cl2N9O33
Formula Weight: 1879.66
MOL File: 91032-36-9.mol

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Teicoplanin A2-3 Property

Density: 1.68±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in ethanol;Soluble in methanol;Soluble in DMSO;Soluble in dimethyl formamide
form: solid
pka: 2.88±0.40(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 20188
Product name: Teicoplanin A2-3
Purity: ≥98%
Packaging: 1mg
Price: $242
Updated: 2024/03/01

Cayman Chemical

Product number: 20188
Product name: Teicoplanin A2-3
Purity: ≥98%
Packaging: 5mg
Price: $965
Updated: 2024/03/01

ApexBio Technology

Product number: C4923
Product name: TeicoplaninA2-3
Packaging: 5mg
Price: $1104
Updated: 2021/12/16

AK Scientific

Product number: 6170CX
Product name: TeicoplaninA2-3
Packaging: 5mg
Price: $1174
Updated: 2021/12/16

ApexBio Technology

Product number: C4923
Product name: TeicoplaninA2-3
Packaging: 1mg
Price: $276
Updated: 2021/12/16

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Teicoplanin A2-3 Chemical Properties,Usage,Production

Uses

Teicoplanin A2-3 is an antibiotic produced by Actinoplanes teichomyceticus.

Uses

Teicoplanin A2-3 is a major analogue of a family of lipoglycopeptides produced by Actinoplanes teichomyceticus. Teicoplanins possess potent broad spectrum antibiotic activity against Gram positive bacteria, including MRSA and E. faecalis.

Definition

ChEBI: A teicoplanin A2 that has decanoyl as the variable N-acyl group.

Biological Activity

teicoplanin a2-3 is a major component of the teicoplanin complex [1-3].teicoplanins, lipoglycopeptide antibiotics, are glycopeptide antibiotics produced by a. teichomyceticus that are broadly effective against gram-positive bacteria in vitro. teicoplanins consist of five major components (a2-1, a2-2, a2-3, a2-4 and a2-5), one hydrolysis component (a3-1), and four minor components (rs-1, rs-2, rs-3, rs-4) [1]. teicoplanins have been recently used for the treatment of multitudinous aerobic and anaerobic gram-positive infections. teicoplanins have been rapidly and extensively absorbed from the peritoneal cavity and muscle, but very poorly absorbed from the gastrointestinal tract [2]. teicoplanin is highly bound in plasma to albumin and in tissues. both renal and nonrenal mechanisms have been implicated in the elimination of the drug. for at least after one day administration, the concentrations of teicoplanin in serum and urine exceeded the mic ranging from 0.02-2 μg/ml on many pathogenic organisms [3].

References

[1] bernareggi a, borghi a, borgonovi m, et al. teicoplanin metabolism in humans[j]. antimicrobial agents and chemotherapy, 1992, 36(8): 1744-1749.
[2] rowland m. clinical pharmacokinetics of teicoplanin[j]. clinical pharmacokinetics, 1990, 18(3): 184-209.
[3] traina g l, bonati m. pharmacokinetics of teicoplanin in man after intravenous administration[j]. journal of pharmacokinetics and pharmacodynamics, 1984, 12(2): 119-128.

Teicoplanin A2-3 Preparation Products And Raw materials

Raw materials

Preparation Products

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Teicoplanin A2-3 Suppliers

China 21 India 2 United Kingdom 1 United States 5 Global 29

ChemStrong Scientific Co.,Ltd

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Lynnchem

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Shenzhen Polymeri Biochemical Technology Co., Ltd.

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BOC Sciences

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Meng Cheng Technology (Shanghai) Co., LTD

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MedBioPharmaceutical Technology Inc

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Shanghai Yifei Biotechnology Co. , Ltd.

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91032-36-9, Teicoplanin A2-3Related Search:

Teicoplanin Teicoplanin A2

Ristomycin A aglycone, 34-O-2-(acetylamino)-2-deoxy-.beta.-D-glucopyranosyl-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-2-deoxy-2-(1-oxodecyl)amino-.beta.-D-glucopyranosyl-42-O-.alpha.-D-mannopyranosyl-

34-O-(2-(Acetylamino)-2-deoxy-beta-D-glucopyranosyl)-22,31-dichloro-7- demethyl-64-O-demethyl-19-deoxy-56-O-(2-deoxy-2-((1-oxodecyl)amino)-be ta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosylristomycin A aglycone

teicoplanin A2-3

Ristomycin A aglycone, 34-O-[2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-[2-deoxy-2-[(1-oxodecyl)amino]-β-D-glucopyranosyl]-42-O-α-D-mannopyranosyl-

Teicoplanin A2-3 DISCONTINUED. Please see T015500

34-O-[2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-[2-deoxy-2-[(1-oxodecyl)amino]-β-D-glucopyranosyl]-42-O-α-D-mannopyranosyl-ristomycinAaglycone

91032-36-9