tert-Butoxy bis(dimethylamino)methane

Product Name: tert-Butoxy bis(dimethylamino)methane
CAS No.: 5815-08-7
Chemical Name: tert-Butoxy bis(dimethylamino)methane
Synonyms: 1-tert-Butoxy-N,N,N',N'-tetramethylmethanediamine;TERT-BUTOXYBIS(DIMETHYLAMINO)METHANE;[(tert-butoxy)(diMethylaMino)Methyl]diMethylaMine;T-BUTOXYBIS(DIMETHYLAMINO)METHANE;BUTOXYBIS(DIMETHYLAMINO)METHANE;5815/8/7;Bredereck'sreagen;BREDERECKS REAGENT;BREDERECK'S REAGENT;Bredereck's reagent
CBNumber: CB0122973
Molecular Formula: C9H22N2O
Formula Weight: 174.28
MOL File: 5815-08-7.mol

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tert-Butoxy bis(dimethylamino)methane Property

Boiling point:: 50-55 °C/15 mmHg (lit.)
Density: 0.844 g/mL at 25 °C (lit.)
refractive index: n20/D 1.422(lit.)
Flash point:: 106 °F
storage temp.: Sealed in dry,Store in freezer, under -20°C
solubility: Chloroform (Sparingly), DMSO (Sparingly), Methanol (Slightly)
pka: 5.46±0.38(Predicted)
form: Liquid
color: Clear pale yellow
Specific Gravity: 0.844
BRN: 1901973
Stability:: Hygroscopic
InChI: InChI=1S/C9H22N2O/c1-9(2,3)12-8(10(4)5)11(6)7/h8H,1-7H3
InChIKey: HXRAMSFGUAOAJR-UHFFFAOYSA-N
SMILES: C(OC(C)(C)C)(N(C)C)N(C)C
CAS DataBase Reference: 5815-08-7(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,F
Risk Statements: 10-36/37/38
Safety Statements: 26
RIDADR: UN 1993 3/PG 3
WGK Germany: 3
F: 10
HazardClass: 3
PackingGroup: III
HS Code: 29221990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 20425
Product name: tert-Butoxy bis(dimethylamino)methane
Purity: technical
Packaging: 10ML
Price: $304
Updated: 2024/03/01

Sigma-Aldrich

Product number: 20425
Product name: tert-Butoxy bis(dimethylamino)methane
Purity: technical
Packaging: 50ML
Price: $1350
Updated: 2024/03/01

Alfa Aesar

Product number: H27861
Product name: tert-Butoxybis(dimethylamino)methane, tech. 90%
Packaging: 1g
Price: $43.65
Updated: 2024/03/01

Alfa Aesar

Product number: H27861
Product name: tert-Butoxybis(dimethylamino)methane, tech. 90%
Packaging: 5g
Price: $114.65
Updated: 2024/03/01

Sigma-Aldrich

Product number: 384216
Product name: tert-Butoxy bis(dimethylamino)methane
Packaging: 1g
Price: $31.5
Updated: 2024/03/01

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tert-Butoxy bis(dimethylamino)methane Chemical Properties,Usage,Production

Description

Bredereck's reagent, chemically known as tert-Butoxy bis(dimethylamino)methane, is a versatile reagent. It can be used for a-methylation, a-methylenation, and a-amidation of multiple carbonyl systems or compounds with active CH groups. The advantage is the in situ generation of strongly basic alkanes (t-BuO-) and the generation of the corresponding iminium ions by thermal decomposition. After the Mannich reaction of the carbonyl substrate with the in situ generated iminium ion, the dimethylamine is eliminated from the adduct B- in the final step to give the condensation product, which can be converted into various types of compounds.

Chemical Properties

Clear pale yellow liquid

Uses

Reactant for:• ;Preparation of pyrroloquinazolines as photochemotherapeutic agents1• ;Enanatioslective formal synthesis of the Cinchona alkaloid quinine via stereoselective intermolecular radical addition2• ;Synthesis of camptothecin via intramolecular isomuenchnone cycloaddition reaction3• ;Aminomethylenation reactions4

Uses

Reactant for:

Preparation of pyrroloquinazolines as photochemotherapeutic agents
Enanatioslective formal synthesis of the Cinchona alkaloid quinine via stereoselective intermolecular radical addition
Synthesis of camptothecin via intramolecular isomuenchnone cycloaddition reaction
Aminomethylenation reactions

Uses

Mild enamination reagent; catalyst in ring-opening polymerization reactions.

tert-Butoxy bis(dimethylamino)methane Preparation Products And Raw materials

Raw materials

Preparation Products

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tert-Butoxy bis(dimethylamino)methane Suppliers

Belgium 1 China 135 Europe 2 France 1 Germany 2 India 6 Japan 1 Poland 1 Switzerland 1 United Kingdom 6 United States 17 Global 173

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Country: Switzerland
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View Lastest Price from tert-Butoxy bis(dimethylamino)methane manufacturers

Shijiazhuang Leon Chemicals Co.,Ltd

Product: Bredereck’s Reagent 5815-08-7
Price: US $10.00-50.00/kg
Min. Order: 1kg
Purity: >90%
Supply Ability: 20 tons
Release date: 2024-08-13

Shanghai UCHEM Inc.

Product: Bredereck's reagent 5815-08-7
Price: US $11.00-190.00/g
Min. Order: 25g
Purity: 0.90
Supply Ability: 200kg
Release date: 2024-04-12

Yujiang Chemical (Shandong) Co.,Ltd.

Product: polyamines
Price: US $1060.00/T
Min. Order: 1T
Purity: 98%
Supply Ability: 20T
Release date: 2024-05-11

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1-tert-Butoxy-N,N,N',N'-tetramethylmethanediamine

1-(tert-Butoxy)-N,N,N',N'-tetramethylmethanediamine 90%

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5815/8/7

tert-Butoxy bis(dimethylamino)methane, 90%, for synthesis

tert-Butoxy bis(dimethyL

Bredereck'sreagen

BREDERECK'S REAGENT ISO 9001：2015 REACH

1-(1,1-Dimethylethoxy)-N,N,N',N'-tetramethyl-methanediamine (contains Tris(dimethylamino) Methane and N,N- Dimethylformamide Di-tert-butyl Acetal) (Technical Grade)

Bredereck's reagent

Methanediamine,1-tert-butoxy-N,N,N',N'-tetramethyl-

1-tert-Butoxy-N,N,N',N'-tetramethylmethanediamine

1-(1,1-Dimethylethoxy)-N,N,N',N'-tetramethyl-methanediamine

5815-08-7

5815-8-7

C9H22N2O

CH33COCHNCH322

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