2-hydroxypentanedioic acid

Product Name: 2-hydroxypentanedioic acid
CAS No.: 13095-47-1
Chemical Name: 2-hydroxypentanedioic acid
Synonyms: R-2-HYDROXYGLUTARATE;D-2-hydroxyglutarate;D--Hydroxyglutaric Acid;D-α-Hydroxyglutaric Acid;D-2-Hydroxyglutaric acid;(2R)-hydroxyglutaric acid;(R)-2-Hydroxyglutaric acid;2-hydroxypentanedioic acid;D-2-Hydroxyglutaric acid D4;D-alpha-Hydroxyglutaric acid
CBNumber: CB01235779
Molecular Formula: C5H8O5
Formula Weight: 148.11
MOL File: 13095-47-1.mol

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2-hydroxypentanedioic acid Property

Boiling point:: 394.2±27.0 °C(Predicted)
Density: 1.508±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Store in freezer, under -20°C
solubility: DMF: 30 mg/mL; DMSO: 30 mg/mL; Ethanol: 30 mg/mL; PBS (pH 7.2): 10 mg/mL
pka: 3.67±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 25895
Product name: D-α-Hydroxyglutaric Acid
Purity: ≥95%
Packaging: 10mg
Price: $139
Updated: 2024/03/01

Cayman Chemical

Product number: 25895
Product name: D-α-Hydroxyglutaric Acid
Purity: ≥95%
Packaging: 25mg
Price: $243
Updated: 2024/03/01

Cayman Chemical

Product number: 25895
Product name: D-α-Hydroxyglutaric Acid
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 25895
Product name: D-α-Hydroxyglutaric Acid
Packaging: 5mg
Price: $100
Updated: 2024/03/01

ChemScene

Product number: CS-0059411
Product name: D-α-Hydroxyglutaricacid
Packaging: 5mg
Price: $90
Updated: 2021/12/16

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2-hydroxypentanedioic acid Chemical Properties,Usage,Production

Uses

2-Hydroxypentanedioic Acid is a mouse metabolite

Definition

ChEBI: (R)-2-hydroxyglutaric acid is the (R)-enantiomer of 2-hydroxyglutaric acid. It has a role as an algal metabolite. It is an enantiomer of a (S)-2-hydroxyglutaric acid.

in vivo

D-α-Hydroxyglutaric acid strongly inhibits glucose utilization, CO₂ production and the respiratory chain in rat cerebral cortex and human skeletal muscle, as well as in submitochondrial particles from bovine heart, suggesting an impairment of the aerobic metabolism^[5].
D-α-Hydroxyglutaric acid has also been proposed as an endogenous excitotoxic organic acid because it significantly decreased cell viability in neuronal cultures from chick embryo telencephalons and from neonatal rat hippocampus through stimulation of specific NMDA glutamate receptors^[5].
D-α-Hydroxyglutaric acid (0.01-1 mM) significantly increases chemiluminescence and thiobarbituric acid-reactive substances (TBA-RS) and decreased total antioxidant reactivity (TAR) values in the cortical supernatants in 30-day-old-rats^[5].

IC 50

Microbial Metabolite; Human Endogenous Metabolite

2-hydroxypentanedioic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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2-hydroxypentanedioic acid Suppliers

China 25 France 1 India 2 United States 3 Global 31

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13095-47-1, 2-hydroxypentanedioic acidRelated Search:

Glutaric acid Nicotinamide 2-hydroxyglutaric acid

2-hydroxypentanedioic acid

D-2-Hydroxyglutaric acid

R-2-HYDROXYGLUTARATE

(R)-2-Hydroxyglutaric acid

(R)-alpha-Hydroxyglutaric acid

D-alpha-Hydroxyglutaric acid

Pentanedioic acid, 2-hydroxy-, (2R)-

D--Hydroxyglutaric Acid

(2R)-hydroxyglutaric acid

D-2-hydroxyglutarate

D-α-Hydroxyglutaric Acid

D-2-Hydroxyglutaric acid D4

13095-47-1