DHEA-S

Product Name: DHEA-S
CAS No.: 651-48-9
Chemical Name: DHEA-S
Synonyms: PB005;PB 005;PB-005;DHEA-S;DHEA-ST;Prasterone sulfate;Formylisoglutamic acid;Abiraterone Impurity 54;Abiraterone Impurity 73;DEHYDROEPIANDROSTERONESULPHATE
CBNumber: CB01235906
Molecular Formula: C19H28O5S
Formula Weight: 368.49
MOL File: 651-48-9.mol

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DHEA-S Property

Boiling point:: 468.81°C (rough estimate)
Density: 1.1763 (rough estimate)
refractive index: 1.5300 (estimate)
Melting point:: 190-192 °C
pka: -3.51±0.18(Predicted)
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: SHG0005097
Product name: DEHYDROEPIANDROSTERONE SULFATE
Purity: 95.00%
Packaging: 5MG
Price: $499.49
Updated: 2021/12/16

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DHEA-S Chemical Properties,Usage,Production

Uses

Dehydroepiandrosterone sulfate, a neuroactive neurosteroid, plays a major role in brain development and aging by influencing the migration of neurons, arborization of dendrites, and formation of new synapses[1][2][3].

Definition

ChEBI: A steroid sulfate that is the 3-sulfooxy derivative of dehydroepiandrosterone.

in vivo

DHEAS chronic administration produces a dose-dependent effect on performance^[3].

Animal Model:	Sixty-four male Sprague-Dawley rats, approximately 90 days of age (300-400 g)^[3].
Dosage:	5, 10, or 20 mg/kg.
Administration:	Subcutaneous injection starting 7 days post-surgery and 1 h prior to all behavioral testing.
Result:	Significantly effective in improving latency to reach the platform as compared to injured rats receiving vehicle.

IC 50

Human Endogenous Metabolite

References

[1] E E Baulieu, et al. Dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) as neuroactive neurosteroids. Proc Natl Acad Sci U S A. 1998 Apr 14;95(8):4089-91. DOI:10.1073/pnas.95.8.4089
[2] C R Parker Jr, et al. Dehydroepiandrosterone and dehydroepiandrosterone sulfate production in the human adrenal during development and aging. Steroids. 1999 Sep;64(9):640-7. DOI:10.1016/s0039-128x(99)00046-x
[3] Stuart W Hoffman, et al. The delayed administration of dehydroepiandrosterone sulfate improves recovery of function after traumatic brain injury in rats. J Neurotrauma. 2003 Sep;20(9):859-70. DOI:10.1089/089771503322385791

DHEA-S Preparation Products And Raw materials

Raw materials

Preparation Products

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DHEA-S Suppliers

China 30 United States 4 Global 34

Sichuan Wei Keqi Biological Technology Co., Ltd.

Tel: 028-81700200 18116577057
Fax: 028-81705658
Email: 3003855609@qq.com
Country: China
ProdList: 7778
Advantage: 56

Hangzhou J&H Chemical Co., Ltd.

Tel: 0571-87396432
Fax: 0571-87396431
Email: sales@jhechem.com
Country: China
ProdList: 14912
Advantage: 59

Codow Chemical Co.,Ltd.

Tel: 18620099427
Fax: +86-20-62619665
Email: amy@howeipharm.com
Country: China
ProdList: 6687
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Shandong JunRui Pharmaceutical Co., Ltd.

Tel: 0539-5636807 15318528770
Fax: 0539-5636807
Email: ffeng813@163.com
Country: China
ProdList: 254
Advantage: 58

Rhawn Reagent

Tel: 400-400-1332688 18019345275
Fax: 400-133-2688
Email: amy@rhawn.cn
Country: China
ProdList: 14948
Advantage: 58

UHN Shanghai Research & Development Co., Ltd.

Tel: 021-58958002 18930822973
Fax: 021-58958618
Email: sales@uhnshanghai.com
Country: China
ProdList: 1984
Advantage: 58

Shanghai Han-Xiang Chemical Co., Ltd.

Tel: 15971444841
Fax: 18327183813
Email: amber@biochempartner.com
Country: China
ProdList: 3061
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

Dideu Industries Group Limited

Tel: +86-29-89586680 +86-15129568250
Email: 1026@dideu.com
Country: China
ProdList: 20284
Advantage: 58

651-48-9, DHEA-SRelated Search:

Phosphoric acid Dehydroepiandrosterone Dehydroepiandrosterone ABiraterone impurity 15 Abiraterone Acetate Dimer Impurity (3β)-Androsta-5,16-diene-3,17-diol 3-Acetate 17-(Trifluoromethanesulfonate) DIETHYL(3-PYRIDYL)BORANE Abiraterone Sulfate Sodium Salt Abiraterone Impurity 4 Abiraterone Ethyl Ether Dehydroepiandrosterone acetate Abiraterone Abiraterone N-Oxide Abiraterone Related CoMpound 2 (Prasterone Triflate) Abiraterone Sulfate Abiraterone Related Compound 8 Abiraterone DiMer IMpurity (Prasteronyl Abiraterone) 17-Iodoandrosta-5,16-dien-3beta-ol

10,13-dimethyl-17-oxo-3-sulfooxy-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene

Formylisoglutamic acid

Dehydroepiandrosterone Sulfate

DEHYDROEPIANDROSTERONESULPHATE

[(3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-oxo-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-yl] hydrogen sulfate

sulfuric acid [(3S,8R,9S,10R,13S,14S)-17-keto-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-yl] ester

(3β)-3-(Sulfooxy)androst-5-en-17-one

Prasterone Sulfate Sports Nutrition Supplements Prasterone Sodium Sulfate 651-48-9

Androst-5-en-17-one, 3-(sulfooxy)-, (3β)-

Abiraterone Impurity 73

Abiraterone Impurity 54

10,13-dimethyl-17-oxo-3-sulfooxy-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene USP/EP/BP

DHEA Sulfate DISCONTINUED. Please see S673250

PB 005

PB005

PB-005

Dehydroisoandrosterone sulfate

Dehydroepiandrosterone sulfate, 10 mM in DMSO

DHEA-S

Dehydroepiandrosterone 3-sulfate

DHEA-ST

Prasterone sulfate

651-48-9

C19H28O5S