ChemicalBook > CAS DataBase List > DHEA-S

DHEA-S

Product Name
DHEA-S
CAS No.
651-48-9
Chemical Name
DHEA-S
Synonyms
PB005;PB 005;PB-005;DHEA-S;DHEA-ST;Prasterone sulfate;Formylisoglutamic acid;Abiraterone Impurity 54;Abiraterone Impurity 73;DEHYDROEPIANDROSTERONESULPHATE
CBNumber
CB01235906
Molecular Formula
C19H28O5S
Formula Weight
368.49
MOL File
651-48-9.mol
More
Less

DHEA-S Property

Boiling point:
468.81°C (rough estimate)
Density 
1.1763 (rough estimate)
refractive index 
1.5300 (estimate)
Melting point:
190-192 °C
pka
-3.51±0.18(Predicted)
form 
Solid
color 
White to off-white
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
SHG0005097
Product name
DEHYDROEPIANDROSTERONE SULFATE
Purity
95.00%
Packaging
5MG
Price
$499.49
Updated
2021/12/16
More
Less

DHEA-S Chemical Properties,Usage,Production

Uses

Dehydroepiandrosterone sulfate, a neuroactive neurosteroid, plays a major role in brain development and aging by influencing the migration of neurons, arborization of dendrites, and formation of new synapses[1][2][3].

Definition

ChEBI: A steroid sulfate that is the 3-sulfooxy derivative of dehydroepiandrosterone.

in vivo

DHEAS chronic administration produces a dose-dependent effect on performance[3].

Animal Model:Sixty-four male Sprague-Dawley rats, approximately 90 days of age (300-400 g)[3].
Dosage:5, 10, or 20 mg/kg.
Administration:Subcutaneous injection starting 7 days post-surgery and 1 h prior to all behavioral testing.
Result:Significantly effective in improving latency to reach the platform as compared to injured rats receiving vehicle.

IC 50

Human Endogenous Metabolite

References

[1] E E Baulieu, et al. Dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) as neuroactive neurosteroids. Proc Natl Acad Sci U S A. 1998 Apr 14;95(8):4089-91. DOI:10.1073/pnas.95.8.4089
[2] C R Parker Jr, et al. Dehydroepiandrosterone and dehydroepiandrosterone sulfate production in the human adrenal during development and aging. Steroids. 1999 Sep;64(9):640-7. DOI:10.1016/s0039-128x(99)00046-x
[3] Stuart W Hoffman, et al. The delayed administration of dehydroepiandrosterone sulfate improves recovery of function after traumatic brain injury in rats. J Neurotrauma. 2003 Sep;20(9):859-70. DOI:10.1089/089771503322385791

DHEA-S Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

DHEA-S Suppliers

TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
Creative Enzymes
Tel
1-516-855-7709
Fax
1-631-938-8127
Email
info@creative-enzymes.com
Country
United States
ProdList
8748
Advantage
58
Creative Enzymes
Tel
--
Fax
--
Email
info@creative-enzymes.com
Country
United States
ProdList
6057
Advantage
58

651-48-9, DHEA-SRelated Search:


  • 10,13-dimethyl-17-oxo-3-sulfooxy-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene
  • Formylisoglutamic acid
  • Dehydroepiandrosterone Sulfate
  • DEHYDROEPIANDROSTERONESULPHATE
  • [(3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-oxo-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-yl] hydrogen sulfate
  • sulfuric acid [(3S,8R,9S,10R,13S,14S)-17-keto-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-yl] ester
  • (3β)-3-(Sulfooxy)androst-5-en-17-one
  • Prasterone Sulfate Sports Nutrition Supplements Prasterone Sodium Sulfate 651-48-9
  • Androst-5-en-17-one, 3-(sulfooxy)-, (3β)-
  • Abiraterone Impurity 73
  • Abiraterone Impurity 54
  • 10,13-dimethyl-17-oxo-3-sulfooxy-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene USP/EP/BP
  • DHEA Sulfate DISCONTINUED. Please see S673250
  • PB 005
  • PB005
  • PB-005
  • Dehydroisoandrosterone sulfate
  • Dehydroepiandrosterone sulfate, 10 mM in DMSO
  • DHEA-S
  • Dehydroepiandrosterone 3-sulfate
  • DHEA-ST
  • Prasterone sulfate
  • 651-48-9
  • C19H28O5S