Resolvin D5
- Product Name
- Resolvin D5
- CAS No.
- 578008-43-2
- Chemical Name
- Resolvin D5
- Synonyms
- Resolvin D5;7(S),17(S)-Resolvin D5;(5Z,7S,8E,10Z,13Z,15E,17S,19Z)-7,17-dihydroxydocosa-5,8,10,13,15,19-hexaenoic acid;4,8,10,13,15,19-Docosahexaenoic acid, 7,17-dihydroxy-, (4Z,7S,8E,10Z,13Z,15E,17S,19Z)-
- CBNumber
- CB01236231
- Molecular Formula
- C22H32O4
- Formula Weight
- 360.49
- MOL File
- 578008-43-2.mol
Resolvin D5 Property
- Boiling point:
- 559.4±50.0 °C(Predicted)
- Density
- 1.048±0.06 g/cm3(Predicted)
- storage temp.
- Store at -80°C,protect from light
- solubility
- DMF: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 0.5 mg/ml
- pka
- 4.58±0.10(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242Use only non-sparking tools.
P243Take precautionary measures against static discharge.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P370+P378In case of fire: Use … for extinction.
P403+P235Store in a well-ventilated place. Keep cool.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 10007280
- Product name
- Resolvin D5
- Purity
- ≥95%
- Packaging
- 10μg
- Price
- $153
- Updated
- 2024/03/01
- Product number
- 10007280
- Product name
- Resolvin D5
- Purity
- ≥95%
- Packaging
- 25μg
- Price
- $362
- Updated
- 2024/03/01
- Product number
- 10007280
- Product name
- Resolvin D5
- Purity
- ≥95%
- Packaging
- 50μg
- Price
- $684
- Updated
- 2024/03/01
- Product number
- 10007280
- Product name
- Resolvin D5
- Purity
- ≥95%
- Packaging
- 100μg
- Price
- $1199
- Updated
- 2024/03/01
- Product number
- R144730
- Product name
- 7(S),17(S)-ResolvinD5
- Packaging
- 0.5mg
- Price
- $16540
- Updated
- 2021/12/16
Resolvin D5 Chemical Properties,Usage,Production
Description
Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA; ) and docosahexaenoic acid (DHA; ). In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state. Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA; ) and docosahexaenoic acid (DHA; ). In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state. Resolvin D5 (RvD5) is a DHA-derived resolvin generated by a double dioxygenation mechanism. RvD5 has been identified in media from ionophore-stimulated trout brain cells, in human synovial fluid from patients with rheumatoid arthritis, and in exudates of bacterial infections in mice. RvD5 stimulates the phagocytosis of E. coli by human macrophages, and RvD5 methyl ester enhances bacterial killing in mice inoculated with E. coli. Analytical and biological comparisons of synthetic RvD5 with endogenously derived RvD5 have confirmed its identity as matching the natural product.
Uses
7(S),17(S)-Resolvin D5 is a docosahexaenoic acid (D494500), which is a ω-3 fatty acid that is found in the brain, synapses, and retina. It also exhibits anti-inflammatory activity.