4H-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-6-beta-D-glucopyranosyl-5 -hydroxy-7-methoxy-
- Product Name
- 4H-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-6-beta-D-glucopyranosyl-5 -hydroxy-7-methoxy-
- CAS No.
- 6980-25-2
- Chemical Name
- 4H-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-6-beta-D-glucopyranosyl-5 -hydroxy-7-methoxy-
- Synonyms
- Swertiajaponin, 10 mM in DMSO;Inhibitor,inhibit,Tyrosinase,Swertiajaponin;3',4',5-Trihydroxy-7-methoxy-6-β-D-glucopyranosylflavone;3',4',5-Trihydroxy-7-methoxy-6-(β-D-glucopyranosyl)flavone;4H-1-Benzopyran-4-one,2-(3,4-dihydroxyphenyl)-6-b-D-glucopyranosyl-5-hydroxy-7-methoxy-;4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-6-β-D-glucopyranosyl-5-hydroxy-7-methoxy-;2-(3,4-Dihydroxyphenyl)-6-(β-D-glucopyranosyl)-5-hydroxy-7-methoxy-4H-1-benzopyran-4-one;4H-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-6-beta-D-glucopyranosyl-5 -hydroxy-7-methoxy-;2-(3,4-Dihydroxyphenyl)-5-hydroxy-7-methoxy-6-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-oneertiajaponin
- CBNumber
- CB01243112
- Molecular Formula
- C22H22O11
- Formula Weight
- 462.4
- MOL File
- 6980-25-2.mol
4H-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-6-beta-D-glucopyranosyl-5 -hydroxy-7-methoxy- Property
- Melting point:
- 270℃ (acetic acid )
- Boiling point:
- 761.3±60.0 °C(Predicted)
- Density
- 1.649±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- Solid
- pka
- 5.74±0.40(Predicted)
- color
- Light yellow to yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- CS-0019510
- Product name
- Swertiajaponin
- Packaging
- 1mg
- Price
- $229
- Updated
- 2021/12/16
- Product number
- CS-0019510
- Product name
- Swertiajaponin
- Packaging
- 5mg
- Price
- $686
- Updated
- 2021/12/16
- Product number
- 4461
- Product name
- Swertiajaponin
- Packaging
- 20mg
- Price
- $690
- Updated
- 2021/12/16
- Product number
- JR8-N1285
- Product name
- Swertiajaponin(NewProduct)
- Purity
- 98%(HPLC)
- Packaging
- 50mg
- Price
- $1280
- Updated
- 2021/12/16
- Product number
- AS021330
- Product name
- Swertiajaponin
- Purity
- 98%
- Packaging
- 1g
- Price
- $1993
- Updated
- 2021/12/16
4H-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-6-beta-D-glucopyranosyl-5 -hydroxy-7-methoxy- Chemical Properties,Usage,Production
Uses
Swertiajaponin is a tyrosinase inhibitor, forms multiple hydrogen bonds and hydrophobic interactions with the binding pocket of tyrosinase, with an IC50 of 43.47 μM. Swertiajaponin also inhibits oxidative stress-mediated MAPK/MITF signaling, leading to decrease in tyrosinase protein level. Swertiajaponin suppresses melanin accumulation and exhibits strong anti-oxidative activity[1].
Definition
ChEBI: A flavone C-glycoside that is isoorientin in which the hydroxy group at position 7 is replaced by a methoxy group.
References
[1] Lee B, et al. Swertiajaponin inhibits skin pigmentation by dual mechanisms to suppress tyrosinase. Oncotarget. 2017 Sep 15;8(56):95530-95541. DOI:10.18632/oncotarget.20913
4H-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-6-beta-D-glucopyranosyl-5 -hydroxy-7-methoxy- Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4H-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-6-beta-D-glucopyranosyl-5 -hydroxy-7-methoxy- manufacturers
- Product
- Swertiajaponin 6980-25-2
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2020-03-24
- Product
- 4H-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-6-beta-D-glucopyranosyl-5 -hydroxy-7-methoxy- 6980-25-2
- Price
- US $6.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1kg, 5kg ,50kg
- Release date
- 2020-03-09