ChemicalBook > CAS DataBase List > 4H-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-6-beta-D-glucopyranosyl-5 -hydroxy-7-methoxy-

4H-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-6-beta-D-glucopyranosyl-5 -hydroxy-7-methoxy-

Product Name
4H-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-6-beta-D-glucopyranosyl-5 -hydroxy-7-methoxy-
CAS No.
6980-25-2
Chemical Name
4H-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-6-beta-D-glucopyranosyl-5 -hydroxy-7-methoxy-
Synonyms
Swertiajaponin, 10 mM in DMSO;Inhibitor,inhibit,Tyrosinase,Swertiajaponin;3',4',5-Trihydroxy-7-methoxy-6-β-D-glucopyranosylflavone;3',4',5-Trihydroxy-7-methoxy-6-(β-D-glucopyranosyl)flavone;4H-1-Benzopyran-4-one,2-(3,4-dihydroxyphenyl)-6-b-D-glucopyranosyl-5-hydroxy-7-methoxy-;4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-6-β-D-glucopyranosyl-5-hydroxy-7-methoxy-;2-(3,4-Dihydroxyphenyl)-6-(β-D-glucopyranosyl)-5-hydroxy-7-methoxy-4H-1-benzopyran-4-one;4H-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-6-beta-D-glucopyranosyl-5 -hydroxy-7-methoxy-;2-(3,4-Dihydroxyphenyl)-5-hydroxy-7-methoxy-6-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-oneertiajaponin
CBNumber
CB01243112
Molecular Formula
C22H22O11
Formula Weight
462.4
MOL File
6980-25-2.mol
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4H-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-6-beta-D-glucopyranosyl-5 -hydroxy-7-methoxy- Property

Melting point:
270℃ (acetic acid )
Boiling point:
761.3±60.0 °C(Predicted)
Density 
1.649±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
form 
Solid
pka
5.74±0.40(Predicted)
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0019510
Product name
Swertiajaponin
Packaging
1mg
Price
$229
Updated
2021/12/16
ChemScene
Product number
CS-0019510
Product name
Swertiajaponin
Packaging
5mg
Price
$686
Updated
2021/12/16
AvaChem
Product number
4461
Product name
Swertiajaponin
Packaging
20mg
Price
$690
Updated
2021/12/16
JR MediChem
Product number
JR8-N1285
Product name
Swertiajaponin(NewProduct)
Purity
98%(HPLC)
Packaging
50mg
Price
$1280
Updated
2021/12/16
Arctom
Product number
AS021330
Product name
Swertiajaponin
Purity
98%
Packaging
1g
Price
$1993
Updated
2021/12/16
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4H-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-6-beta-D-glucopyranosyl-5 -hydroxy-7-methoxy- Chemical Properties,Usage,Production

Uses

Swertiajaponin is a tyrosinase inhibitor, forms multiple hydrogen bonds and hydrophobic interactions with the binding pocket of tyrosinase, with an IC50 of 43.47 μM. Swertiajaponin also inhibits oxidative stress-mediated MAPK/MITF signaling, leading to decrease in tyrosinase protein level. Swertiajaponin suppresses melanin accumulation and exhibits strong anti-oxidative activity[1].

Definition

ChEBI: A flavone C-glycoside that is isoorientin in which the hydroxy group at position 7 is replaced by a methoxy group.

References

[1] Lee B, et al. Swertiajaponin inhibits skin pigmentation by dual mechanisms to suppress tyrosinase. Oncotarget. 2017 Sep 15;8(56):95530-95541. DOI:10.18632/oncotarget.20913

4H-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-6-beta-D-glucopyranosyl-5 -hydroxy-7-methoxy- Preparation Products And Raw materials

Raw materials

Preparation Products

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4H-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-6-beta-D-glucopyranosyl-5 -hydroxy-7-methoxy- Suppliers

Chengdu Biopurify Phytochemicals Ltd.
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+86-028-82633397 18982077548
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+86-28-82633165
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cwb1@biopurify.cn
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China
ProdList
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60
Shanghai Tauto Biotech Co., Ltd.
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021-51320588
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0086-21-51320502
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tauto@tautobiotech.com
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China
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Cheng Du Pufeide Biotechnology Co., Ltd.
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028-82610909 13388174823
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8171-1798
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scglp@glp-china.com
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China
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Bide Pharmatech Ltd.
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400-400-164-7117 18317119277
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+86-21-61629029
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China
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Sichuan Wei Keqi Biological Technology Co., Ltd.
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028-81700200 18116577057
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028-81705658
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3003855609@qq.com
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China
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Wuxi Zhongkun Biochemical Technology Co., Ltd.
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0510-85629785 18013409632
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051085625359
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sales@reading-chemicals.com
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China
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Finetech Industry Limited
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027-87465837 19945049750
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027-8777-2287
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sales@finetechnology-ind.com
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China
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Shanghai Yongye Biotechnology Co., Ltd.
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86-021-61559134 15921386130
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021-55068248
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3423497944@qq.com
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China
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Wuhan ChemFaces Biochemical Co., Ltd.
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18607101326 15172504745
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+86-27-84254680
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aileen@chemfaces.com
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China
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6905
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EMMX Biotechnology LLC
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888-539-0666
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888-539-0666
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info@emmx.com
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United States
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8447
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View Lastest Price from 4H-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-6-beta-D-glucopyranosyl-5 -hydroxy-7-methoxy- manufacturers

Shanghai Standard Technology Co., Ltd.
Product
Swertiajaponin 6980-25-2
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2020-03-24
Career Henan Chemical Co
Product
4H-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-6-beta-D-glucopyranosyl-5 -hydroxy-7-methoxy- 6980-25-2
Price
US $6.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1kg, 5kg ,50kg
Release date
2020-03-09

6980-25-2, 4H-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-6-beta-D-glucopyranosyl-5 -hydroxy-7-methoxy-Related Search:


  • 4H-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-6-beta-D-glucopyranosyl-5 -hydroxy-7-methoxy-
  • 2-(3,4-Dihydroxyphenyl)-6-(β-D-glucopyranosyl)-5-hydroxy-7-methoxy-4H-1-benzopyran-4-one
  • 3',4',5-Trihydroxy-7-methoxy-6-(β-D-glucopyranosyl)flavone
  • 3',4',5-Trihydroxy-7-methoxy-6-β-D-glucopyranosylflavone
  • 4H-1-Benzopyran-4-one,2-(3,4-dihydroxyphenyl)-6-b-D-glucopyranosyl-5-hydroxy-7-methoxy-
  • 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-6-β-D-glucopyranosyl-5-hydroxy-7-methoxy-
  • Inhibitor,inhibit,Tyrosinase,Swertiajaponin
  • 2-(3,4-Dihydroxyphenyl)-5-hydroxy-7-methoxy-6-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-oneertiajaponin
  • Swertiajaponin, 10 mM in DMSO
  • 6980-25-2
  • Penta-substituted Flavones