ChemicalBook > CAS DataBase List > (S)-Lansoprazole

(S)-Lansoprazole

Product Name
(S)-Lansoprazole
CAS No.
138530-95-7
Chemical Name
(S)-Lansoprazole
Synonyms
S-Isomer: 008;(S)-Lansoprazole;Levolansoprazole;(-)-Lansoprazole;D4-(S)-Lansoprazole;Lansoprazole S-Isome;Lansoprazole S-IsoMer;Lansoprazole Impurity 15;Lansoprazole impurity 58;Dexlansoprazole Impurity 8
CBNumber
CB01269822
Molecular Formula
C16H14F3N3O2S
Formula Weight
369.36
MOL File
138530-95-7.mol
More
Less

(S)-Lansoprazole Property

Melting point:
60-65°C
Boiling point:
555.8±60.0 °C(Predicted)
Density 
1.50±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Store in freezer, under -20°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
9.56±0.10(Predicted)
color 
Beige to Light Brown
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Cayman Chemical
Product number
21967
Product name
(S)-Lansoprazole
Purity
≥98%
Packaging
500μg
Price
$91
Updated
2024/03/01
Cayman Chemical
Product number
21967
Product name
(S)-Lansoprazole
Purity
≥98%
Packaging
1mg
Price
$166
Updated
2024/03/01
Cayman Chemical
Product number
21967
Product name
(S)-Lansoprazole
Purity
≥98%
Packaging
5mg
Price
$781
Updated
2024/03/01
Cayman Chemical
Product number
21967
Product name
(S)-Lansoprazole
Purity
≥98%
Packaging
10mg
Price
$1301
Updated
2024/03/01
Medical Isotopes, Inc.
Product number
65808
Product name
(S)-Lansoprazole
Packaging
10mg
Price
$2120
Updated
2021/12/16
More
Less

(S)-Lansoprazole Chemical Properties,Usage,Production

Description

(S)-Lansoprazole is a proton pump inhibitor that irreversibly inhibits H+/K+-stimulated ATPase pumps in parietal cells (IC50 = 5.2 μM), inhibiting gastric acid secretion and increasing intragastric pH. It also inhibits acid formation in isolated canine parietal cells (IC50 = 82 μM). (S)-Lansoprazole is an enantiomerically pure form of lansoprazole . Both (S)- and (R)-lansoprazole are pharmacologically active with similar potencies.

Chemical Properties

Light Brown Solid

Uses

The S-enantiomer of Lansoprazole; a gastric proton pump inhibitor. An antiulcerative.

in vivo

Lansoprazole (20-40 mg/kg) treatment significantly attenuated STZ and HFD -induced memory deficits, biochemical and histopathological alterations[3].
Lansoprazole (20 mg/kg and 40 mg/kg, p.o.) significantly reduces the STZ and HFD- induced increase in AChE activity[3].
Lansoprazole (20 mg/kg and 40 mg/kg, p.o.) significantly reduces the STZ and HFD- induced rise in brain MPO level[3].
Further HFD mice treated with lansoprazole (20 mg/kg and 40 mg/kg, p.o.) shows a marked decrease in the body weight in comparison to the control animals[3].

References

[1] SCHUBERT M L. Pharmacotherapy for acid/peptic disorders.[J]. Yale Journal of Biology and Medicine, 1996, 69 2: 197-201.

(S)-Lansoprazole Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(S)-Lansoprazole Suppliers

Canada 1 China 80 India 5 United Kingdom 2 United States 8 Global 96
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Cato Research Chemicals Inc.
Tel
020-81960175
Fax
+1-541-2553641
Email
min.he@cato-chem.com
Country
China
ProdList
1955
Advantage
55
Zhengzhou Topcare Pharmaceutical Co.,Ltd.
Tel
0371-60942985
Fax
0371-60942986,qq1994339443
Country
China
ProdList
54
Advantage
58
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
18333
Advantage
56
Shanghai Huilun Life Science&Technology Co.Ltd.
Tel
021-64160263-8087
Fax
021-34304236
Email
api@hllife.com.cn
Country
China
ProdList
70
Advantage
60
Nanjing Chalf-Pharm Technology Co., Ltd.
Tel
025-57018978 18251899859
Fax
025-57018008
Email
sales@chalf-pharm.com
Country
China
ProdList
5674
Advantage
50
Nanjing XiZe Biotechnology CO., Ltd.
Tel
025-58362220 0086-15250997978
Fax
025-58362220
Email
sale@njxizebio.com
Country
China
ProdList
4855
Advantage
55
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9923
Advantage
65
Artis Biotech Co. Ltd.
Tel
028-67271278 18628360895
Fax
0575-89298961
Email
sales@artisbio.com
Country
China
ProdList
1960
Advantage
58

138530-95-7, (S)-LansoprazoleRelated Search:

R-(+)-Lansoprazole (R)-Tomoxetine Lansoprazole (R,S)-N-Acetyl-3,4-dimethoxy phenylalanine Levodopa 5-HYDROXY LANSOPRAZOLE 1H-Benzimidazole-2-sulfinicacid(9CI) Des(trifluoroethyl) Lansoprazole Sulfide 2-Hydroxybenzimidazole 2-Desethoxy-2-hydroxy-1H-1-Ethyl Candesartan Cilexetil 2-[[[4-(2,2,2-Trifluoroethoxy)-3-Methyl-1-oxopyridin-2-yl]Methyl]sulfanyl]-1H-benziMidazole LANSOPRAZOLE SULFONE 2-Hydroxymethyl-3-methyl-4-(2,2,2-trifluoroethoxy)pyridine hydrochloride OPD EASY-tablets Lercanidipine IMpurity B 4-Desmethoxypropoxyl-4-chloro Rabeprazole Lansoprazole N-Oxide 1H-BenziMidazole, 2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]Methyl]sulfinyl]-1-(2,2,2-trifluoroethyl)-

  • (S)-Lansoprazole
  • 2-[(S)-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]Methyl]sulfinyl]-
  • Lansoprazole S-IsoMer
  • (S)-2-(((3-Methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole
  • Lansoprazole Impurity 15
  • 1H-Benzimidazole, 2-[(S)-[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]- (9CI)
  • 1H-Benzimidazole, 2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-, (S)-
  • Levolansoprazole
  • 2-[(S)-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole
  • (S)-2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]-1H-benzimidazole
  • Lansoprazole S-Isome
  • levogyration lansoprazole Impurity 10
  • 1H-Benzimidazole, 2-[(S)-[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-
  • Dexlansoprazole Impurity 8
  • S-Isomer: 008
  • Lansoprazole S-Isomer/ Levolansoprazole
  • (S)-LansoprazoleQ: What is (S)-Lansoprazole Q: What is the CAS Number of (S)-Lansoprazole Q: What is the storage condition of (S)-Lansoprazole Q: What are the applications of (S)-Lansoprazole
  • (-)-Lansoprazole
  • Lansoprazole impurity 58
  • Levolansoprazole, 10 mM in DMSO
  • (S)-Lansoprazole， Levolansoprazole
  • D4-(S)-Lansoprazole
  • 138530-95-7
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Sulfur & Selenium Compounds