5-Benzothiazolecarbonitrile,2-chloro-(9CI)
Uses- Product Name
- 5-Benzothiazolecarbonitrile,2-chloro-(9CI)
- CAS No.
- 385432-46-2
- Chemical Name
- 5-Benzothiazolecarbonitrile,2-chloro-(9CI)
- Synonyms
- SKL221;2-CHLORO-5-CYANOBENZOTHIAZOLE;5-Benzothiazolecarbonitrile, 2-chloro-;2-Chlorobenzo[d]thiazole-5-carbonitrile;2-chloro-1,3-benzothiazole-5-carbonitrile;5-Benzothiazolecarbonitrile,2-chloro-(9CI)
- CBNumber
- CB01275832
- Molecular Formula
- C8H3ClN2S
- Formula Weight
- 194.64
- MOL File
- 385432-46-2.mol
5-Benzothiazolecarbonitrile,2-chloro-(9CI) Property
- Boiling point:
- 336.6±15.0 °C(Predicted)
- Density
- 1.51±0.1 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- -1.68±0.10(Predicted)
- Appearance
- Light yellow to yellow Solid
N-Bromosuccinimide Price
- Product number
- C651818
- Product name
- 2-Chlorobenzo[d]thiazole-5-carbonitrile
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 4992AB
- Product name
- 2-Chlorobenzo[d]thiazole-5-carbonitrile
- Packaging
- 250mg
- Price
- $155
- Updated
- 2021/12/16
- Product number
- HCH0363657
- Product name
- 2-CHLOROBENZO[D]THIAZOLE-5-CARBONITRILE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $503.25
- Updated
- 2021/12/16
- Product number
- A390819
- Product name
- 2-Chlorobenzo[d]thiazole-5-carbonitrile
- Purity
- 97%
- Packaging
- 5g
- Price
- $607
- Updated
- 2021/12/16
- Product number
- CM125154
- Product name
- 2-chlorobenzo[d]thiazole-5-carbonitrile
- Purity
- 98%
- Packaging
- 5g
- Price
- $748
- Updated
- 2021/12/16
5-Benzothiazolecarbonitrile,2-chloro-(9CI) Chemical Properties,Usage,Production
Uses
2-Chlorobenzo[d]thiazole-5-carbonitrile is a useful research chemical.
Synthesis
149367-90-8
385432-46-2
To a solution of 2-thio-2,3-dihydrobenzo[d]thiazole-5-carbonitrile (1.0 g, 5.2 mmol) in dichloromethane (10 mL) was slowly added sulfonyl chloride (13.5 g, 100 mmol) at 0 °C. The reaction mixture was then warmed to 25 °C and stirred continuously for 3 hours. Upon completion of the reaction, the mixture was poured into water (200 mL) and the dichloromethane was removed by partial vacuum concentration. The aqueous phase was extracted with ethyl acetate (3 x 90 mL) and the organic phases were combined. The organic phase was washed sequentially with brine (3 x 20 mL), dried over anhydrous sodium sulfate, filtered and concentrated in vacuum. The crude product was purified by silica gel column chromatography with the eluent ratio of petroleum ether:ethyl acetate=15:1 to 10:1 to afford 2-chlorobenzo[d]thiazole-5-carbonitrile (0.4 g, 40% yield) as a yellow solid.1H-NMR (CDCl3, 400MHz): δ 8.26 (d, J=0.8 Hz, 1H), 7.92 (d, J=8.4 Hz, 1H), 7.68 (d, J=8.4 Hz, 1H), 1H), 7.68 (d, J=8.4 Hz, 1H). 1H), 7.68 (dd, J=8.4, 1.6 Hz, 1H).
References
[1] Patent: WO2017/69980, 2017, A1. Location in patent: Paragraph 00317; 00318
5-Benzothiazolecarbonitrile,2-chloro-(9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-Benzothiazolecarbonitrile,2-chloro-(9CI) manufacturers
- Product
- 5-Benzothiazolecarbonitrile,2-chloro-(9CI) 385432-46-2
- Price
- US $1.00-2.00/KG
- Min. Order
- 1KG
- Purity
- 95%-99%
- Supply Ability
- 100kg
- Release date
- 2019-08-28