ChemicalBook > CAS DataBase List > 1,2-Benzisothiazol-5-amine(9CI)

1,2-Benzisothiazol-5-amine(9CI)

Product Name
1,2-Benzisothiazol-5-amine(9CI)
CAS No.
53473-85-1
Chemical Name
1,2-Benzisothiazol-5-amine(9CI)
Synonyms
1,2-benzothiazol-5-amine;benzo[d]isothiazol-5-amine;1,2-Benzisothiazol-5-amine;1,2-Benzisothiazole-5-aMine;5-Amino-1,2-benzisothiazole;Benzo[d]isothiazol-5-ylaMine;1,2-Benzisothiazol-5-amine(9CI)
CBNumber
CB01299593
Molecular Formula
C7H6N2S
Formula Weight
150.2
MOL File
53473-85-1.mol
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1,2-Benzisothiazol-5-amine(9CI) Property

Boiling point:
232.5±22.0 °C(Predicted)
Density 
1.383
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
pka
5.20±0.33(Predicted)
Appearance
Light brown to brown Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
B343710
Product name
Benzo[d]isothiazol-5-amine
Packaging
10mg
Price
$45
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0094420
Product name
1,2-BENZISOTHIAZOL-5-AMINE
Purity
95.00%
Packaging
5MG
Price
$503.93
Updated
2021/12/16
AK Scientific
Product number
7613AB
Product name
Benzo[d]isothiazol-5-amine
Packaging
2.5g
Price
$1256
Updated
2021/12/16
AK Scientific
Product number
7613AB
Product name
Benzo[d]isothiazol-5-amine
Packaging
5g
Price
$1796
Updated
2021/12/16
Ambeed
Product number
A134624
Product name
Benzo[d]isothiazol-5-amine
Purity
95%
Packaging
100mg
Price
$62
Updated
2021/12/16
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1,2-Benzisothiazol-5-amine(9CI) Chemical Properties,Usage,Production

Synthesis

60768-66-3

53473-85-1

5-Nitrobenzo[d]isothiazole (305 mg, 1.69 mmol) was added with iron powder (325 mesh, 473 mg), 5% aqueous acetic acid (12 mL) and ethyl acetate (12 mL), and the reaction was rapidly stirred for 1 hour at 65 °C. After completion of the reaction, the mixture was cooled to room temperature, diluted with water and ethyl acetate and filtered through diatomaceous earth. The organic layer was separated and the aqueous layer was extracted with additional ethyl acetate. The organic extracts were combined, washed with brine, dried over anhydrous magnesium sulfate, and concentrated in vacuo to give 1,2-benzisothiazol-5-amine as a yellow solid (220 mg, 85% yield).Mass spectral data for 1,2-benzisothiazol-5-amine: m/z MS (ESI): 151 ([M + H]+).

References

[1] Patent: WO2007/39563, 2007, A1. Location in patent: Page/Page column 17
[2] Patent: US2007/112019, 2007, A1. Location in patent: Page/Page column 9/1
[3] Patent: WO2017/218960, 2017, A1. Location in patent: Paragraph 00425

1,2-Benzisothiazol-5-amine(9CI) Preparation Products And Raw materials

Raw materials

Preparation Products

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1,2-Benzisothiazol-5-amine(9CI) Suppliers

JinYan Chemicals(ShangHai) Co.,Ltd.
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+86 (531) 55696010 QQ 1762738062
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China
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ChemShuttle, Inc.
Tel
0510-83588313-811 18800520310
Email
sales@chemshuttle.com
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Atop-Pharma (Shanghai) Technology Co., Ltd.
Tel
+86 (21) 5196-9732
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53473-85-1, 1,2-Benzisothiazol-5-amine(9CI)Related Search:


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