ChemicalBook > CAS DataBase List > 1H-Pyrazole-4-carboxylicacid,1,3-dimethyl-(9CI)

1H-Pyrazole-4-carboxylicacid,1,3-dimethyl-(9CI)

Product Name
1H-Pyrazole-4-carboxylicacid,1,3-dimethyl-(9CI)
CAS No.
78703-53-4
Chemical Name
1H-Pyrazole-4-carboxylicacid,1,3-dimethyl-(9CI)
Synonyms
BAS 04879380;1,3-dimethyl-4-pyrazolecarboxylic acid;1,3-Dimethyl-1H-pyrazol-4-carboxylic acid;1H-Pyrazole-4-carboxylic acid,1,3-dimethyl-;1H-Pyrazole-4-carboxylicacid,1,3-dimethyl-(9CI);1,3-Dimethyl-1H-pyrazole-4-carboxylic acid AldrichCPR;Pyrazole acid (1,3-dimethyl-1H-pyrazole-4-carboxylic acid);1,3-dimethyl-1H-pyrazole-4-carboxylic acid(SALTDATA: FREE)
CBNumber
CB01300491
Molecular Formula
C6H8N2O2
Formula Weight
140.14
MOL File
78703-53-4.mol
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1H-Pyrazole-4-carboxylicacid,1,3-dimethyl-(9CI) Property

Melting point:
182 °C
Boiling point:
299.2±20.0 °C(Predicted)
Density 
1.28±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
3?+-.0.25(Predicted)
color 
Pale Yellow to Yellow
InChI
InChI=1S/C6H8N2O2/c1-4-5(6(9)10)3-8(2)7-4/h3H,1-2H3,(H,9,10)
InChIKey
YALJPBXSARRWTA-UHFFFAOYSA-N
SMILES
N1(C)C=C(C(O)=O)C(C)=N1
CAS DataBase Reference
78703-53-4
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Safety

WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
2933199090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
CBR00325
Product name
1,3-Dimethyl-1H-pyrazole-4-carboxylic acid
Purity
AldrichCPR
Packaging
1g
Price
$128
Updated
2025/07/31
TRC
Product number
D479318
Product name
1,3-Dimethyl-1H-pyrazole-4-carboxylic acid
Packaging
100mg
Price
$45
Updated
2021/12/16
TRC
Product number
D479318
Product name
1,3-Dimethyl-1H-pyrazole-4-carboxylic acid
Packaging
250mg
Price
$50
Updated
2021/12/16
Matrix Scientific
Product number
027192
Product name
1,3-Dimethyl-1H-pyrazole-4-carboxylic acid
Packaging
500mg
Price
$54
Updated
2021/12/16
Matrix Scientific
Product number
027192
Product name
1,3-Dimethyl-1H-pyrazole-4-carboxylic acid
Packaging
1g
Price
$82
Updated
2021/12/16
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1H-Pyrazole-4-carboxylicacid,1,3-dimethyl-(9CI) Chemical Properties,Usage,Production

Synthesis

85290-76-2

78703-53-4

The general procedure for the synthesis of 1,3-dimethyl-1H-pyrazole-4-carboxylic acid from ethyl 1,3-dimethyl-1H-pyrazole-4-carboxylate is as follows: ethyl 1,3-dimethyl-1H-pyrazole-4-carboxylate (2) was stirred in an ethanol solution of sodium hydroxide for 12 hours at room temperature. After completion of the reaction, the solvent ethanol was removed by distillation under reduced pressure. The remaining solid was dissolved in an appropriate amount of water and hydrochloric acid was added slowly to a pH of about 2, at which time a white solid 1,3-dimethyl-1H-pyrazole-4-carboxylic acid (3) precipitated. The precipitate was collected by filtration and washed with cold water and finally dried in a vacuum drying oven to give the target product 1,3-dimethyl-1H-pyrazole-4-carboxylic acid (3).

References

[1] Journal of Heterocyclic Chemistry, 2018, vol. 55, # 4, p. 946 - 950
[2] Molecules, 2015, vol. 20, # 3, p. 4383 - 4394
[3] Patent: CN107033082, 2017, A. Location in patent: Paragraph 0015; 0016; 0028
[4] Patent: CN107033084, 2017, A. Location in patent: Paragraph 0029
[5] Patent: CN106632044, 2017, A. Location in patent: Paragraph 0014

1H-Pyrazole-4-carboxylicacid,1,3-dimethyl-(9CI) Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 1H-Pyrazole-4-carboxylicacid,1,3-dimethyl-(9CI) manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
1H-Pyrazole-4-carboxylicacid,1,3-dimethyl-(9CI) 78703-53-4
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000KGS
Release date
2025-05-20
Career Henan Chemical Co
Product
1H-Pyrazole-4-carboxylicacid,1,3-dimethyl-(9CI) 78703-53-4
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kg
Release date
2019-12-30

78703-53-4, 1H-Pyrazole-4-carboxylicacid,1,3-dimethyl-(9CI)Related Search:

ETHYL 1,3,5-TRIMETHYL-1H-PYRAZOLE-4-CARBOXYLATE 5-CHLORO-1,3-DIMETHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID 5-CHLORO-1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID 1,3,5-Trimethyl-1H-pyrazole-4-carboxylic acid 1H-Pyrazole-4-carboxylicacid,1,3-dimethyl-(9CI) 1-BENZYL-3,5-DIMETHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID 5-(4-CHLOROPHENOXY)-1,3-DIMETHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID 1,3-DIPHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID AKOS B025767 RARECHEM AL BI 0565 5-(3-CHLOROPHENOXY)-1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID 1H-PYRAZOLE-4-CARBOXYLIC ACID, 5-METHYL-1,3-DIPHENYL-, ETHYL ESTER 5-CHLORO-3-METHYL-1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID 5-METHYL-1,3-DIPHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL 1-(4-AMINOPHENYL)-3,5-DIMETHYL-1H-PYRAZOLE-4-CARBOXYLATE O1-([5-CHLORO-1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-4-YL]CARBONYL)-4-(TRIFLUOROMETHYL)BENZENE-1-CARBOHYDROXIMAMIDE 1,3-DIMETHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER O1-([5-CHLORO-1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-4-YL]CARBONYL)-4-CHLOROBENZENE-1-CARBOHYDROXIMAMIDE

  • 1H-Pyrazole-4-carboxylicacid,1,3-dimethyl-(9CI)
  • 1,3-dimethyl-1H-pyrazole-4-carboxylic acid(SALTDATA: FREE)
  • 1,3-Dimethyl-1H-pyrazole-4-carboxylic acid AldrichCPR
  • 1,3-dimethyl-4-pyrazolecarboxylic acid
  • BAS 04879380
  • 1H-Pyrazole-4-carboxylic acid,1,3-dimethyl-
  • 1,3-Dimethyl-1H-pyrazol-4-carboxylic acid
  • Pyrazole acid (1,3-dimethyl-1H-pyrazole-4-carboxylic acid)
  • 78703-53-4
  • CARBOXYLICACID