ChemicalBook > CAS DataBase List > isoleucyl-lysyl-valyl-alanyl-valine
isoleucyl-lysyl-valyl-alanyl-valine
- Product Name
- isoleucyl-lysyl-valyl-alanyl-valine
- CAS No.
- 131167-89-0
- Chemical Name
- isoleucyl-lysyl-valyl-alanyl-valine
- Synonyms
- Laminin-1 peptide;H-Ile-Lys-Val-Ala-Val-OH;isoleucyl-lysyl-valyl-alanyl-valine;Laminin α-1 Chain (2099-2103) (human);L-Isoleucyl-L-lysyl-L-valyl-L-alanyl-L-valine;L-Valine, L-isoleucyl-L-lysyl-L-valyl-L-alanyl-
- CBNumber
- CB01307889
- Molecular Formula
- C25H48N6O6
- Formula Weight
- 528.69
- MOL File
- 131167-89-0.mol
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isoleucyl-lysyl-valyl-alanyl-valine Property
- form
- Solid
- color
- White to off-white
- Sequence
- H-Ile-Lys-Val-Ala-Val-OH
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isoleucyl-lysyl-valyl-alanyl-valine Chemical Properties,Usage,Production
Uses
H-Ile-Lys-Val-Ala-Val-OH is one of the most potent active sites of laminin-1. H-Ile-Lys-Val-Ala-Val-OH promotes cell adhesion, neurite outgrowth, and tumor growth. H-Ile-Lys-Val-Ala-Val-OH stimulates BMMSC population growth and proliferation by activating MAPK/ERK1/2 and PI3K/Akt signalling pathways[1][2].
IC 50
ERK1; ERK2; Akt
References
[1] Nomizu M, et al. The all-D-configuration segment containing the IKVAV sequence of laminin A chain has similar activities to the all-L-peptide in vitro and in vivo. J Biol Chem. 1992 Jul 15;267(20):14118-21. PMID:1629212
[2] Li B, et al. IKVAV regulates ERK1/2 and Akt signalling pathways in BMMSC population growth and proliferation. Cell Prolif. 2014 Apr;47(2):133-45. DOI:10.1111/cpr.12094
isoleucyl-lysyl-valyl-alanyl-valine Preparation Products And Raw materials
Raw materials
Preparation Products
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isoleucyl-lysyl-valyl-alanyl-valine Suppliers
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View Lastest Price from isoleucyl-lysyl-valyl-alanyl-valine manufacturers
zhuzhou dingcheng meihei comestic co.,ltd
- Product
- Laminin-1 peptide 131167-89-0
- Price
- US $33.00/Box
- Min. Order
- 1Box
- Purity
- 99.99%
- Supply Ability
- 10000000000
- Release date
- 2023-12-06
Shanghai Getian Industrial Co., LTD
- Product
- isoleucyl-lysyl-valyl-alanyl-valine 131167-89-0
- Price
- US $23.00/Box
- Min. Order
- 1Box
- Purity
- 99%
- Supply Ability
- 10000Box
- Release date
- 2024-04-28