cyclopenin

Product Name: cyclopenin
CAS No.: 20007-87-8
Chemical Name: cyclopenin
Synonyms: NSC114538;NSC604989;NSC-604989;cyclopenin;NSC-114538;NSC 604989;NSC 114538;Spiro[3H-1,4-benzodiazepine-3,2'-oxirane]-2,5(1H,4H)-dione, 4-methyl-3'-phenyl-, (2'R,3'S)-rel-(-)-
CBNumber: CB01316133
Molecular Formula: C17H14N2O3
Formula Weight: 294.31
MOL File: 20007-87-8.mol

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cyclopenin Property

Melting point:: 183-184 °C
Boiling point:: 572.5±50.0 °C(Predicted)
Density: 1.40±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO: soluble
form: A solid
pka: 12.92±0.40(Predicted)
biological source: plant
Water Solubility: water: slightly soluble

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SMB01003
Product name: Cyclopenin
Purity: ≥90% (LC/MS-ELSD)
Packaging: 1 mg
Price: $313
Updated: 2025/07/31

Cayman Chemical

Product number: 23145
Product name: Cyclopenin
Purity: ≥99%
Packaging: 5mg
Price: $301
Updated: 2024/03/01

Cayman Chemical

Product number: 23145
Product name: Cyclopenin
Purity: ≥99%
Packaging: 25mg
Price: $1050
Updated: 2024/03/01

Usbiological

Product number: 207140
Product name: Cyclopenin
Packaging: 1mg
Price: $329
Updated: 2021/12/16

Usbiological

Product number: C8845-50
Product name: Cyclopenin
Packaging: 5mg
Price: $453
Updated: 2021/12/16

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cyclopenin Chemical Properties,Usage,Production

Description

Cyclopenin is an inhibitor of acetylcholinesterase (AChE; IC₅₀ = 2.04 μM for human recombinant AChE) that is produced by Penicillium. It exhibits greater than 2,000-fold selectivity over recombinant equine butyrylcholinesterase with an IC₅₀ value greater than 4,080 μM. Cyclopenin also has antibacterial activity against E. coli and M. pyogenes.

Uses

(-)-Cyclopenin ((-)-Cyclopenine) is the enantiomer of Cyclopenin. Cyclopenin is a selective acetylcholinesterase (AChE) inhibitor with the IC50 of 2.04 μM[1].

Definition

ChEBI: (-)-cyclopenine is an epoxide.

References

[1] F Kuno, et al. Arisugacins A and B, novel and selective acetylcholinesterase inhibitors from Penicillium sp. FO-4259. II. Structure elucidation. J Antibiot (Tokyo). 1996 Aug;49(8):748-51. DOI:10.7164/antibiotics.49.748

cyclopenin Preparation Products And Raw materials

Raw materials

Preparation Products

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cyclopenin Suppliers

China 27 United States 4 Global 31

Shanghai Hongye Biotechnology Co. Ltd

Tel: 400-9205774
Email: sales@glpbio.cn
Country: China
ProdList: 6777
Advantage: 58

BOC Sciences

Tel: 16314854226; +16314854226
Email: inquiry@bocsci.com
Country: United States
ProdList: 19654
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32470
Advantage: 58

Zhejiang Huida Biotech Co., LTD

Tel: 0571-89903882 18679456698
Email: mingxinzhu@huidabiotech.com
Country: China
ProdList: 2975
Advantage: 58

Zhejiang Huida Biotech Co., LTD

Tel: 0571-0571-89903882 15990081639
Email: sunshixuan@huidabiotech.com
Country: China
ProdList: 3705
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24961
Advantage: 58

Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Country: China
ProdList: 11973
Advantage: 58

Adipogen Life Sciences

Tel: 41-6192660-40
Email: info@adipogen.com
Country: China
ProdList: 5293
Advantage: 58

Cayman Chemical Company

Tel: 800-364-9897
Email: sales@caymanchem.com
Country: China
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Funakoshi Co Ltd

Tel: 81356846296
Email: export@funakoshi.co.jp
Country: China
ProdList: 2347
Advantage: 58

20007-87-8, cyclopeninRelated Search:

cyclopenin

Spiro[3H-1,4-benzodiazepine-3,2'-oxirane]-2,5(1H,4H)-dione, 4-methyl-3'-phenyl-, (2'R,3'S)-rel-(-)-

NSC 114538

NSC 604989

NSC114538

NSC-114538

NSC604989

NSC-604989

20007-87-8

2007-87-8