tilivalline
- Product Name
- tilivalline
- CAS No.
- 80279-24-9
- Chemical Name
- tilivalline
- Synonyms
- tilivalline;(6S,6aS)-4-hydroxy-6-(1H-indol-3-yl)-5,6,6a,7,8,9-hexahydropyrrolo[2,1-c][1,4]benzodiazepin-11-one;5H-Pyrrolo[2,1-c][1,4]benzodiazepin-5-one, 1,2,3,10,11,11a-hexahydro-9-hydroxy-11-(1H-indol-3-yl)-, (11S,11aS)-
- CBNumber
- CB01319129
- Molecular Formula
- C20H19N3O2
- Formula Weight
- 333.38
- MOL File
- 80279-24-9.mol
tilivalline Property
- Melting point:
- >215°C (dec.)
- storage temp.
- Hygroscopic, Refrigerator, Under inert atmosphere
- solubility
- DMSO (Slightly), Methanol (Slightly, Sonicated)
- form
- Solid
- color
- Pale Beige to Light Brown
- Stability:
- Hygroscopic
N-Bromosuccinimide Price
- Product number
- T440350
- Product name
- Tilivalline
- Packaging
- 1mg
- Price
- $180
- Updated
- 2021/12/16
- Product number
- T440350
- Product name
- Tilivalline
- Packaging
- 10mg
- Price
- $1390
- Updated
- 2021/12/16
- Product number
- 72673
- Product name
- Tilivalline
- Packaging
- 50mg
- Price
- $2400
- Updated
- 2021/12/16
tilivalline Chemical Properties,Usage,Production
Uses
Tilivalline, is a metabolite from Klebsiella oxytoca. Tilivalline, is shown to be cytotoxin, and the key event causing Antibiotic-Associated Hemorrhagic Colitis.
Definition
ChEBI: Tilivalline is a pyrrolobenzodiazepine that is (11aS)-2,3,5,10,11,11a-hexahydro-1H-pyrrolo[2,1-c][1,4]benzodiazepine substituted by an oxo group at position 5, by a hydroxy group at position 9, and by a 1H-indol-3-yl group at position 11S. It is a natural product discovered in Klebsiella oxytoca which is the causative toxin in antibiotic associated hemorrhagic colitis. It exhibits a microtubule-stabilizing activity that leads to mitotic arrest in the host cells. It has a role as a microtubule-stabilising agent, a toxin and a bacterial metabolite. It is a pyrrolobenzodiazepine, a member of phenols, an indole alkaloid and a member of indoles.
tilivalline Preparation Products And Raw materials
Raw materials
Preparation Products
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