Raloxifene-d10
- Product Name
- Raloxifene-d10
- CAS No.
- 2512224-37-0
- Chemical Name
- Raloxifene-d10
- Synonyms
- Raloxifene-d10-1;[4-[2-(2,2,3,3,4,4,5,5,6,6-decadeuteriopiperidin-1-yl)ethoxy]phenyl]-[6-hydroxy-2-(4-hydroxyphenyl)-1-benzothiophen-3-yl]methanone
- CBNumber
- CB013226835
- Molecular Formula
- C28H17D10NO4S
- Formula Weight
- 483.65
- MOL File
- 2512224-37-0.mol
Raloxifene-d10 Property
- Boiling point:
- 728.193±60.00 °C(Press: 760.00 Torr)(predicted)
- Density
- 1.289±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
Raloxifene-d10 Chemical Properties,Usage,Production
Uses
Raloxifene-d10-1 is the deuterium labeled Raloxifene[1]. Raloxifene (Keoxifene) is a benzothiophene-derived selective estrogen receptor modulator (SERM). Raloxifene has estrogen-agonistic effects on bone and lipids and estrogen-antagonistic effects on the breast and uterus. Raloxifene is used for breast cancer and osteoporosis research[2].
References
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. DOI:10.1177/1060028018797110
[2] Khovidhunkit W, et al. Clinical effects of raloxifene hydrochloride in women. Ann Intern Med. 1999;130(5):431-439. DOI:10.7326/0003-4819-130-5-199903020-00015
[3] Xu H, et al. Effect of caffeine on ovariectomy-induced osteoporosis in rats. Biomed Pharmacother. 2019112:108650. DOI:10.1016/j.biopha.2019.108650
Raloxifene-d10 Preparation Products And Raw materials
Raw materials
Preparation Products
Raloxifene-d10 Suppliers
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- 028-83243028 19136088901
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- Country
- China
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- China
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