vinaxanthone
- Product Name
- vinaxanthone
- CAS No.
- 133293-89-7
- Chemical Name
- vinaxanthone
- Synonyms
- vinaxanthone;5,7-Diacetyl-6-(5-carboxy-6,7-dihydroxy-4-oxo-4H-chromen-3-yl)-2,3-dihydroxy-9-oxo-9H-xanthene-1-carboxylic acid;9H-Xanthene-1-carboxylic acid, 5,7-diacetyl-6-(5-carboxy-6,7-dihydroxy-4-oxo-4H-1-benzopyran-3-yl)-2,3-dihydroxy-9-oxo-
- CBNumber
- CB01325917
- Molecular Formula
- C28H16O14
- Formula Weight
- 576.42
- MOL File
- 133293-89-7.mol
vinaxanthone Property
- form
- Solid
- color
- Light yellow to yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- INB0003993
- Product name
- VINAXANTHONE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $504.72
- Updated
- 2021/12/16
vinaxanthone Chemical Properties,Usage,Production
Uses
Vinaxanthone is used in the pharmaceutical composition containing xanthone compound SM-345431 for treating cerebral infarction.
in vivo
Vinaxanthone (SM-345431) (0.1 mg/mL, Subconjunctival injections, every 2 days, 3 weeks) accelerates peripheral nerve regeneration and sensitivity in a murine corneal transplantation model[4].
Vinaxanthone (SEMA3A-I) (20 μg, i.p.) protects from Doxorubicin (HY-15142A)-induced podocyte injury through an anti-apoptosis mechanism in mouse model of Doxorubicin (HY-15142A)-induced podocytopathy[5].
| Animal Model: | murine corneal transplantation model[4] |
| Dosage: | 0.1 mg/mL |
| Administration: | Subconjunctival injections, every 2 days, 3 weeks |
| Result: | Showed significantly higher nerve growth. Improved the corneal sensitivity. |
| Animal Model: | mouse model of Doxorubicin (10 mg/kg)-induced podocytopathy[5] |
| Dosage: | 20 μg |
| Administration: | Intraperitoneal injection (i.p.), every day |
| Result: | Improved the expression of nephrin. Reduced podocytopathy and tubular casts. Detected rarely TUNEL-positive cells in the Dox + Vinaxanthone group. Had fewer p-c-Jun-positive cells in the Dox + Vinaxanthone group. |
vinaxanthone Preparation Products And Raw materials
Raw materials
Preparation Products
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