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vinaxanthone

Product Name
vinaxanthone
CAS No.
133293-89-7
Chemical Name
vinaxanthone
Synonyms
vinaxanthone;5,7-Diacetyl-6-(5-carboxy-6,7-dihydroxy-4-oxo-4H-chromen-3-yl)-2,3-dihydroxy-9-oxo-9H-xanthene-1-carboxylic acid;9H-Xanthene-1-carboxylic acid, 5,7-diacetyl-6-(5-carboxy-6,7-dihydroxy-4-oxo-4H-1-benzopyran-3-yl)-2,3-dihydroxy-9-oxo-
CBNumber
CB01325917
Molecular Formula
C28H16O14
Formula Weight
576.42
MOL File
133293-89-7.mol
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vinaxanthone Property

form 
Solid
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
INB0003993
Product name
VINAXANTHONE
Purity
95.00%
Packaging
5MG
Price
$504.72
Updated
2021/12/16
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vinaxanthone Chemical Properties,Usage,Production

Uses

Vinaxanthone is used in the pharmaceutical composition containing xanthone compound SM-?345431 for treating cerebral infarction.

in vivo

Vinaxanthone (SM-345431) (0.1 mg/mL, Subconjunctival injections, every 2 days, 3 weeks) accelerates peripheral nerve regeneration and sensitivity in a murine corneal transplantation model[4].
Vinaxanthone (SEMA3A-I) (20 μg, i.p.) protects from Doxorubicin (HY-15142A)-induced podocyte injury through an anti-apoptosis mechanism in mouse model of Doxorubicin (HY-15142A)-induced podocytopathy[5].

Animal Model:murine corneal transplantation model[4]
Dosage:0.1 mg/mL
Administration: Subconjunctival injections, every 2 days, 3 weeks
Result:Showed significantly higher nerve growth.
Improved the corneal sensitivity.
Animal Model: mouse model of Doxorubicin (10 mg/kg)-induced podocytopathy[5]
Dosage:20 μg
Administration:Intraperitoneal injection (i.p.), every day
Result:Improved the expression of nephrin.
Reduced podocytopathy and tubular casts.
Detected rarely TUNEL-positive cells in the Dox + Vinaxanthone group.
Had fewer p-c-Jun-positive cells in the Dox + Vinaxanthone group.

vinaxanthone Preparation Products And Raw materials

Raw materials

Preparation Products

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vinaxanthone Suppliers

China 8 South Korea 1 United States 2 Global 11
CHEMICAL LAND21
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Email
sales21@chemicalland21.com
Country
South Korea
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133293-89-7, vinaxanthoneRelated Search:

2-HYDROXY-5-METHYLISOPHTHALALDEHYDE 4-Benzoylbenzylamine hydrochloride 2-Bibenzylcarboxylic acid 2-(4-METHYLPHENOXY)BENZENECARBALDEHYDE 1,3,5-TRIACETYLBENZENE 2,5-DIMETHYL-P-ANISALDEHYDE 4-ETHYLPHENYLACETONE 2-Ethyl-3-methoxybenzoic acid 3-Methoxy-2-methylbenzoic acid BIS(2-FORMYLPHENYL) ETHER 2,5-Dihydroxybenzoic acid 2-HYDROXY-5-METHYLBENZOPHENONE 2'-HYDROXY-4',5'-DIMETHYLACETOPHENONE 4-(2-PHENYLETHYL)BENZOPHENONE 1-(2,4-DIHYDROXYPHENYL)-2-P-TOLYLETHANONE 2-METHOXY-5-METHYLISOPHTHALALDEHYDE 2-HYDROXY-1,3,5-BENZENETRICARBALDEHYDE O-PROPIONYLBENZOIC ACID

  • vinaxanthone
  • 9H-Xanthene-1-carboxylic acid, 5,7-diacetyl-6-(5-carboxy-6,7-dihydroxy-4-oxo-4H-1-benzopyran-3-yl)-2,3-dihydroxy-9-oxo-
  • 5,7-Diacetyl-6-(5-carboxy-6,7-dihydroxy-4-oxo-4H-chromen-3-yl)-2,3-dihydroxy-9-oxo-9H-xanthene-1-carboxylic acid
  • 133293-89-7
  • C28H16O14