2-hydroxy-1-naphthalaldehyde salicyloylhydrazone

Product Name: 2-hydroxy-1-naphthalaldehyde salicyloylhydrazone
CAS No.: 54009-54-0
Chemical Name: 2-hydroxy-1-naphthalaldehyde salicyloylhydrazone
Synonyms: HNASH;SD49-7;(E/Z)-NSAH;SD49-7, 10 mM in DMSO;2-hydroxy-1-naphthalaldehyde salicyloylhydrazone;2-Hydroxy-N'-((2-hydroxynaphthalen-1-yl)methylene)benzohydrazide;Benzoic acid, 2-hydroxy-, 2-[(2-hydroxy-1-naphthalenyl)methylene]hydrazide
CBNumber: CB01335804
Molecular Formula: C18H14N2O3
Formula Weight: 306.32
MOL File: 54009-54-0.mol

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2-hydroxy-1-naphthalaldehyde salicyloylhydrazone Property

Density: 1.28±0.1 g/cm3(Predicted)
pka: 7.85±0.50(Predicted)

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Hazard and Precautionary Statements (GHS)

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2-hydroxy-1-naphthalaldehyde salicyloylhydrazone Chemical Properties,Usage,Production

Uses

(E/Z)-NSAH is an isoform of NSAH (HY-114503), which is reversible and competitive nonnucleoside ribonucleotide reductase (RR) inhibitor, with cell-free IC50 of 32 μM and cell-based IC50 of ~250 nM, respectively[1].

References

[1] Md Faiz Ahmad, et al. Potent competitive inhibition of human ribonucleotide reductase by a nonnucleoside small molecule. Proc Natl Acad Sci U S A. 2017 Aug 1;114(31):8241-8246. DOI:10.1073/pnas.1620220114

2-hydroxy-1-naphthalaldehyde salicyloylhydrazone Preparation Products And Raw materials

Raw materials

Preparation Products

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2-hydroxy-1-naphthalaldehyde salicyloylhydrazone Suppliers

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54009-54-0, 2-hydroxy-1-naphthalaldehyde salicyloylhydrazoneRelated Search:

2-hydroxy-1-naphthalaldehyde salicyloylhydrazone

Benzoic acid, 2-hydroxy-, 2-[(2-hydroxy-1-naphthalenyl)methylene]hydrazide

SD49-7

(E/Z)-NSAH

2-Hydroxy-N'-((2-hydroxynaphthalen-1-yl)methylene)benzohydrazide

HNASH

SD49-7, 10 mM in DMSO

54009-54-0