dianemycin
- Product Name
- dianemycin
- CAS No.
- 35865-33-9
- Chemical Name
- dianemycin
- Synonyms
- genomycin;Nsc138320;dianemycin;Nanchangmycin free acid;Dianemycin, 10 mM in DMSO;Nanchangmycin >=98% (HPLC);Dianemycin (Synonyms: Nanchangmycin free acid);Antibiotic,Dianemycin,Nanchangmycin,Bacterial,inhibit,Inhibitor;6-Nonenoic acid, 8-[(2S,2'R,4'S,5R,5'S,7R,7'R,8R,9S,9'S,10'R)-9-hydroxy-2,4',8,10'-tetramethyl-2'-[(2S,3S,5R,6R)-tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-9'-[[(2S,5S,6R)-tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl]oxy][2,7'-bi-1,6-dioxaspiro[4.5]dec]-7-yl]-2,4,6-trimethyl-5...
- CBNumber
- CB01337464
- Molecular Formula
- C47H78O14
- Formula Weight
- 867.11
- MOL File
- 35865-33-9.mol
dianemycin Property
- Boiling point:
- 700.37°C (rough estimate)
- Density
- 1.0559 (rough estimate)
- refractive index
- 1.6130 (estimate)
- storage temp.
- Store at -20°C
- solubility
- DMSO: 155 mg/mL (178.75 mM); Water: < 0.1 mg/mL (insoluble)
- form
- Solid
- pka
- 4.59±0.21(Predicted)
- color
- White to off-white
N-Bromosuccinimide Price
- Product number
- SML2251
- Product name
- Nanchangmycin
- Purity
- ≥98% (HPLC)
- Packaging
- 5 mg
- Price
- $125.4
- Updated
- 2025/07/31
- Product number
- SML2251
- Product name
- Nanchangmycin
- Purity
- ≥98% (HPLC)
- Packaging
- 25 mg
- Price
- $528
- Updated
- 2025/07/31
- Product number
- CS-0043615
- Product name
- Dianemycin
- Purity
- >98.0%
- Packaging
- 5mg
- Price
- $200
- Updated
- 2021/12/16
- Product number
- CS-0043615
- Product name
- Dianemycin
- Purity
- >98.0%
- Packaging
- 10mg
- Price
- $350
- Updated
- 2021/12/16
- Product number
- API0013224
- Product name
- DIANEMYCIN
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $498.97
- Updated
- 2021/12/16
dianemycin Chemical Properties,Usage,Production
Uses
Dianemycin (Nanchangmycin free acid), a polyether antibiotic produced by Streptomyces nanchangensis NS3226, inhibits gram-positive bacteria[1]. Nanchangmycin is a broad spectrum antiviral active against Zika virus[2].
Biological Activity
Dianemycin (Nanchangmycin free acid) is a polyether antibiotic produced by Streptomyces nanchangensis NS3226, which inhibits Gram-positive bacteria. It is also a broad-spectrum antiviral drug against Zika virus.
in vitro
Dianemycin (Nanchangmycin) can be used as a growth promotant in poultry and to cure coccidiosis in chickens. It is active against drug resistant strains of malaria.
target
Bacteria
Zika virus
References
[1] Liu T, et al. Mechanism of thioesterase-catalyzed chain release in the biosynthesis of the polyether antibiotic Nanchangmycin. Chem Biol. 2008 May;15(5):449-58. DOI:10.1016/j.chembiol.2008.04.006
[2] Rausch K, et al. Screening Bioactives Reveals Nanchangmycin as a Broad Spectrum Antiviral Active against Zika Virus. Cell Rep. 2017 Jan 17;18(3):804-815. DOI:10.1016/j.celrep.2016.12.068
dianemycin Preparation Products And Raw materials
Raw materials
Preparation Products
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