ChemicalBook > CAS DataBase List > 1-(4-carboxyphenyl)-3,3-dimethyltriazene
1-(4-carboxyphenyl)-3,3-dimethyltriazene
- Product Name
- 1-(4-carboxyphenyl)-3,3-dimethyltriazene
- CAS No.
- 7203-91-0
- Chemical Name
- 1-(4-carboxyphenyl)-3,3-dimethyltriazene
- Synonyms
- CB10-277;1-(4-carboxyphenyl)-3,3-dimethyltriazene;Benzoic acid, 4-(3,3-dimethyl-1-triazen-1-yl)-
- CBNumber
- CB01355158
- Molecular Formula
- C9H11N3O2
- Formula Weight
- 193.2
- MOL File
- 7203-91-0.mol
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N-Bromosuccinimide Price
American Custom Chemicals Corporation
- Product number
- CHM0297090
- Product name
- 4-(DIMETHYLAMINODIAZENYL)BENZOIC ACID
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $505.48
- Updated
- 2021/12/16
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1-(4-carboxyphenyl)-3,3-dimethyltriazene Chemical Properties,Usage,Production
Uses
CB10-277 is a Dacarbazine (HY-B0078) analog that mediates alkylation of guanine residues at the O6 position in DNA and subsequently reduces ATase levels in lymphocytes and tumors. CB10-277 is useful in the study of metastatic malignant melanoma[1].
References
[1] Siow Ming, et al. "In vivo depletion of O 6-alkylguanine-DNA-alkyltransferase in lymphocytes and melanoma of patients treated with CB 10-277, a new DTIC analogue." Cancer chemotherapy and pharmacology 31 (1992): 240-246. DOI:10.1007/BF00685554
1-(4-carboxyphenyl)-3,3-dimethyltriazene Preparation Products And Raw materials
Raw materials
Preparation Products
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