ChemicalBook > CAS DataBase List > 4-amidinoindan-1-one 2'-amidinohydrazone
4-amidinoindan-1-one 2'-amidinohydrazone
- Product Name
- 4-amidinoindan-1-one 2'-amidinohydrazone
- CAS No.
- 149400-88-4
- Chemical Name
- 4-amidinoindan-1-one 2'-amidinohydrazone
- Synonyms
- SAM 486A;CGP 48664;SardoMozide;Sardomozide (CGP-48664;4-amidinoindan-1-one 2'-amidinohydrazone;(E)-2-(4-carbaMiMidoyl-2,3-dihydro-1H-inden-1-ylidene)hydrazinec;2-(4-carbamimidoyl-2,3-dihydro-1H-inden-1-ylidene)hydrazinecarboximidamide;(E)-2-(4-carbamimidoyl-2,3-dihydro-1H-inden-1-ylidene)hydrazinecarboximidamide;Hydrazinecarboximidamide, 2-[4-(aminoiminomethyl)-2,3-dihydro-1H-inden-1-ylidene]-
- CBNumber
- CB01356458
- Molecular Formula
- C11H14N6
- Formula Weight
- 230.274
- MOL File
- 149400-88-4.mol
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4-amidinoindan-1-one 2'-amidinohydrazone Property
- Boiling point:
- 438.8±55.0 °C(Predicted)
- Density
- 1.54±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- solubility
- Soluble in DMSO
- pka
- 11.54±0.20(Predicted)
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N-Bromosuccinimide Price
American Custom Chemicals Corporation
- Product number
- API0009240
- Product name
- SAM-486A
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $402.02
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- API0009240
- Product name
- SAM-486A
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $805
- Updated
- 2021/12/16
Ambeed
- Product number
- A332744
- Product name
- Sardomozide
- Purity
- 95+%
- Packaging
- 1mg
- Price
- $70
- Updated
- 2021/12/16
Ambeed
- Product number
- A332744
- Product name
- Sardomozide
- Purity
- 95+%
- Packaging
- 5mg
- Price
- $163
- Updated
- 2021/12/16
CSNpharm
- Product number
- CSN13147
- Product name
- Sardomozide
- Packaging
- 5mg
- Price
- $181
- Updated
- 2021/12/16
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4-amidinoindan-1-one 2'-amidinohydrazone Chemical Properties,Usage,Production
Biological Activity
Sardomozide is an S-adenosylmethionine decarboxylase (SAMDC) inhibitor with IC50 of 5 nM.
in vitro
Sardomozide is a S-adenosylmethionine decarboxylase (SAMDC) inhibitor with an IC 50 of 5 nM in cell assay. Following treatment for 48 h with 3 μM Sardomozide, intracellular SAMDC activity is reduced to 10% of control. When the CHO/664 cells are grown in the presence of Sardomozide and during treatment with DENSPM, vacuole formation is not observed, and these cells are growth-inhibited and contain levels of DENSPM similar to the parental CHO cells.
target
IC50: 5 nM (SAMDC)
4-amidinoindan-1-one 2'-amidinohydrazone Preparation Products And Raw materials
Raw materials
Preparation Products
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4-amidinoindan-1-one 2'-amidinohydrazone Suppliers
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