ChemicalBook > CAS DataBase List > KB 3022

KB 3022

Product Name
KB 3022
CAS No.
101001-34-7
Chemical Name
KB 3022
Synonyms
KB 3022;KBT-3022;KB3022 (KBT3022;Pamicogrel, 10 mM in DMSO;ethyl 2-[4,5-bis(4-methoxyphenyl)thiazol-2-yl]-pyrrole-1-acetate;Cyclooxygenase,KBT-3022,Pamicogrel,Inhibitor,inhibit,KBT 3022,COX;ethyl 2-(2-(4,5-bis(4-methoxyphenyl)thiazol-2-yl)-1H-pyrrol-1-yl)acetate;2-[4,5-Bis(4-methoxyphenyl)thiazol-2-yl]-1H-pyrrole-1-acetic acid ethyl ester;1H-Pyrrole-1-acetic acid, 2-[4,5-bis(4-methoxyphenyl)-2-thiazolyl]-, ethyl ester
CBNumber
CB01374324
Molecular Formula
C25H24N2O4S
Formula Weight
448.53
MOL File
101001-34-7.mol
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KB 3022 Property

Melting point:
132.5-135.5°
Boiling point:
600.3±65.0 °C(Predicted)
Density 
1.22±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMF:10.0(Max Conc. mg/mL);22.0(Max Conc. mM)
DMF:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);1.1(Max Conc. mM)
DMSO:5.0(Max Conc. mg/mL);11.0(Max Conc. mM)
form 
A crystalline solid
pka
2.68±0.10(Predicted)
color 
Off-white to pink
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Safety

Toxicity
LD50 orally in male mice: >3000 mg/kg (Yoshino)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

ChemScene
Product number
CS-7238
Product name
Pamicogrel
Purity
99.44%
Packaging
5mg
Price
$250
Updated
2021/12/16
ChemScene
Product number
CS-7238
Product name
Pamicogrel
Purity
99.44%
Packaging
10mg
Price
$450
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0012174
Product name
PAMICOGREL
Purity
95.00%
Packaging
5MG
Price
$500.01
Updated
2021/12/16
ChemScene
Product number
CS-7238
Product name
Pamicogrel
Purity
99.44%
Packaging
25mg
Price
$850
Updated
2021/12/16
ChemScene
Product number
CS-7238
Product name
Pamicogrel
Purity
99.44%
Packaging
50mg
Price
$1350
Updated
2021/12/16
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KB 3022 Chemical Properties,Usage,Production

Biological Activity

Pamicogrel (KBT3022) is an inhibitor of cyclooxygenase (COX) with platelet anti-aggregation properties.

in vitro

KB 3022 is a cyclooxygenase inhibitor with platelet anti-aggregatory properties which is under development by Kanebo for chronic arterial occlusion. It also has potential in both prophylaxis and treatment of ischemic brain injury.

target

KB 3022 Preparation Products And Raw materials

Raw materials

Preparation Products

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KB 3022 Suppliers

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101001-34-7, KB 3022Related Search:

2-pyrrol-1-ylacetic acid KB 3022 4,5-DIPHENYL-2-METHYLTHIAZOLE 4-(4-METHOXY-PHENYL)-2-METHYL-THIAZOLE

  • KB 3022
  • 2-[4,5-Bis(4-methoxyphenyl)thiazol-2-yl]-1H-pyrrole-1-acetic acid ethyl ester
  • KBT-3022
  • ethyl 2-(2-(4,5-bis(4-methoxyphenyl)thiazol-2-yl)-1H-pyrrol-1-yl)acetate
  • ethyl 2-[4,5-bis(4-methoxyphenyl)thiazol-2-yl]-pyrrole-1-acetate
  • KB3022 (KBT3022
  • 1H-Pyrrole-1-acetic acid, 2-[4,5-bis(4-methoxyphenyl)-2-thiazolyl]-, ethyl ester
  • Cyclooxygenase,KBT-3022,Pamicogrel,Inhibitor,inhibit,KBT 3022,COX
  • Pamicogrel, 10 mM in DMSO
  • 101001-34-7
    • TargetValue
    COX
    ()