KB 3022
- Product Name
- KB 3022
- CAS No.
- 101001-34-7
- Chemical Name
- KB 3022
- Synonyms
- KB 3022;KBT-3022;KB3022 (KBT3022;ethyl 2-[4,5-bis(4-methoxyphenyl)thiazol-2-yl]-pyrrole-1-acetate;Cyclooxygenase,KBT-3022,Pamicogrel,Inhibitor,inhibit,KBT 3022,COX;ethyl 2-(2-(4,5-bis(4-methoxyphenyl)thiazol-2-yl)-1H-pyrrol-1-yl)acetate;2-[4,5-Bis(4-methoxyphenyl)thiazol-2-yl]-1H-pyrrole-1-acetic acid ethyl ester;1H-Pyrrole-1-acetic acid, 2-[4,5-bis(4-methoxyphenyl)-2-thiazolyl]-, ethyl ester
- CBNumber
- CB01374324
- Molecular Formula
- C25H24N2O4S
- Formula Weight
- 448.53
- MOL File
- 101001-34-7.mol
KB 3022 Property
- Melting point:
- 132.5-135.5°
- Boiling point:
- 600.3±65.0 °C(Predicted)
- Density
- 1.22±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMF:10.0(Max Conc. mg/mL);22.0(Max Conc. mM)
DMF:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);1.1(Max Conc. mM)
DMSO:5.0(Max Conc. mg/mL);11.0(Max Conc. mM) - form
- A crystalline solid
- pka
- 2.68±0.10(Predicted)
Safety
- Toxicity
- LD50 orally in male mice: >3000 mg/kg (Yoshino)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- CS-7238
- Product name
- Pamicogrel
- Purity
- 99.44%
- Packaging
- 5mg
- Price
- $250
- Updated
- 2021/12/16
- Product number
- CS-7238
- Product name
- Pamicogrel
- Purity
- 99.44%
- Packaging
- 10mg
- Price
- $450
- Updated
- 2021/12/16
- Product number
- API0012174
- Product name
- PAMICOGREL
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $500.01
- Updated
- 2021/12/16
- Product number
- CS-7238
- Product name
- Pamicogrel
- Purity
- 99.44%
- Packaging
- 25mg
- Price
- $850
- Updated
- 2021/12/16
- Product number
- CS-7238
- Product name
- Pamicogrel
- Purity
- 99.44%
- Packaging
- 50mg
- Price
- $1350
- Updated
- 2021/12/16
KB 3022 Chemical Properties,Usage,Production
Biological Activity
Pamicogrel (KBT3022) is an inhibitor of cyclooxygenase (COX) with platelet anti-aggregation properties.
in vitro
KB 3022 is a cyclooxygenase inhibitor with platelet anti-aggregatory properties which is under development by Kanebo for chronic arterial occlusion. It also has potential in both prophylaxis and treatment of ischemic brain injury.
target
| Target | Value |
| COX () |