ChemicalBook > CAS DataBase List > 2-{[5,6-BIS(4-METHOXYPHENYL)FURO[2,3-D]PYRIMIDIN-4-YL]AMINO}ETHANOL
2-{[5,6-BIS(4-METHOXYPHENYL)FURO[2,3-D]PYRIMIDIN-4-YL]AMINO}ETHANOL
- Product Name
- 2-{[5,6-BIS(4-METHOXYPHENYL)FURO[2,3-D]PYRIMIDIN-4-YL]AMINO}ETHANOL
- CAS No.
- 378775-98-5
- Chemical Name
- 2-{[5,6-BIS(4-METHOXYPHENYL)FURO[2,3-D]PYRIMIDIN-4-YL]AMINO}ETHANOL
- Synonyms
- AK-IN-1;WAY-239320;TOSLAB 99449;2-{[5,6-BIS(4-METHOXYPHENYL)FURO[2,3-D]PYRIMIDIN-4-YL]AMINO}ETHANOL;Ethanol, 2-[[5,6-bis(4-methoxyphenyl)furo[2,3-d]pyrimidin-4-yl]amino]-;2-((5,6-Bis(4-methoxyphenyl)furo[2,3-d]pyrimidin-4-yl)amino)ethan-1-ol
- CBNumber
- CB0140324
- Molecular Formula
- C22H21N3O4
- Formula Weight
- 391.42
- MOL File
- Mol file
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2-{[5,6-BIS(4-METHOXYPHENYL)FURO[2,3-D]PYRIMIDIN-4-YL]AMINO}ETHANOL Property
- Boiling point:
- 593.0±50.0 °C(Predicted)
- Density
- 1.284±0.06 g/cm3(Predicted)
- pka
- 14.50±0.10(Predicted)
- form
- Solid
- color
- White to off-white
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2-{[5,6-BIS(4-METHOXYPHENYL)FURO[2,3-D]PYRIMIDIN-4-YL]AMINO}ETHANOL Chemical Properties,Usage,Production
Uses
AK-IN-1 (compound 4072-2732) is an adenosine kinase (AK) inhibitor that is competitive for adenosine (Ado) but not for ATP. AK-IN-1 inhibits 86%, 87% and 89% of AK activity at concentrations of 2, 4 and 10 μM, respectively. AK-IN-1 has good potential for research in many disease areas, including ischaemia, inflammation and seizures[1].
References
[1] Park J, et al. Identification and biochemical studies on novel non-nucleoside inhibitors of the enzyme adenosine kinase. Protein J. 2007 Apr;26(3):203-12. DOI:10.1007/s10930-006-9062-z
2-{[5,6-BIS(4-METHOXYPHENYL)FURO[2,3-D]PYRIMIDIN-4-YL]AMINO}ETHANOL Preparation Products And Raw materials
Raw materials
Preparation Products
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2-{[5,6-BIS(4-METHOXYPHENYL)FURO[2,3-D]PYRIMIDIN-4-YL]AMINO}ETHANOL Suppliers
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