6-CHLOROTHYMINE
- Product Name
- 6-CHLOROTHYMINE
- CAS No.
- 1627-28-7
- Chemical Name
- 6-CHLOROTHYMINE
- Synonyms
- EOS-62068;6-CHLOROTHYMINE;6-Chloro-5-Methyluracil;6-CHLOROTHYMINE ISO 9001：2015 REACH;6-Chloro-5-Methyl-1H-pyriMidine-2,4-dione;6-CHLORO-5-METHYL-2,4(1H,3H)-PYRIMIDINEDIONE;6-Chloro-5-methylpyrimidine-2,4(1H,3H)-dione;2,4(1H,3H)-Pyrimidinedione, 6-chloro-5-methyl-
- CBNumber
- CB01417548
- Molecular Formula
- C5H5ClN2O2
- Formula Weight
- 160.56
- MOL File
- 1627-28-7.mol
6-CHLOROTHYMINE Property
- Melting point:
- 266-267 °C(Solv: water (7732-18-5))
- Density
- 1.49±0.1 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 6.52±0.10(Predicted)
- Appearance
- White to off-white Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- FC153218
- Product name
- 6-Chlorothymine
- Packaging
- 2mg
- Price
- $59
- Updated
- 2021/12/16
- Product number
- FC153218
- Product name
- 6-Chlorothymine
- Packaging
- 5mg
- Price
- $117
- Updated
- 2021/12/16
- Product number
- FC153218
- Product name
- 6-Chlorothymine
- Packaging
- 10mg
- Price
- $203
- Updated
- 2021/12/16
- Product number
- FC153218
- Product name
- 6-Chlorothymine
- Packaging
- 25mg
- Price
- $405
- Updated
- 2021/12/16
- Product number
- HCH0126054
- Product name
- 2,4(1H,3H)-PYRIMIDINEDIONE, 6-CHLORO-5-METHYL-
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $496.21
- Updated
- 2021/12/16
6-CHLOROTHYMINE Chemical Properties,Usage,Production
Synthesis
2417-22-3
1627-28-7
The general procedure for the synthesis of 6-chloro-5-methylpyrimidine-2,4(1H,3H)-dione from 5-methylbarbituric acid (CAS:2417-22-3) was as follows: under nitrogen protection, 5-methylbarbituric acid (9.40 g, 0.066 mol) and benzyltriethylammonium chloride (BTAC) (30.14 g, 0.13 mol) were suspended in trichloro phosphorus oxide (POCl3) (154 mL, 1.65 mol) and heated at 50 °C with stirring for 7 hours. Upon completion of the reaction, the mixture was cooled to room temperature and evaporated to dryness under vacuum. The residue was carefully quenched with 285 g of ice water at 0 °C and the slurry was subsequently placed in a refrigerator overnight. The precipitate was collected by filtration, washed with cold water and dried under vacuum in the presence of phosphorus pentoxide to give 6-chloro-5-methylpyrimidine-2,4(1H,3H)-dione (5.60 g, 0.035 mol, 53% yield) as a white solid. The melting point of the product was 270-272 °C. 1H NMR (300 MHz, DMSO-d6) δ (ppm): 11.81 (br s, 1H, NH), 11.32 (br s, 1H, NH), 1.82 (s, 3H, CH3). IR (KBr, ν cm-1): 3158 (NH), 3013,2814 (Csp2-H ), 1711,1647 (C=O), 1625 (C=C), 1491 (NH), 1424 (C-N), 891 (NH), 753 (C-Cl).
References
[1] European Journal of Medicinal Chemistry, 2012, vol. 54, p. 159 - 174
6-CHLOROTHYMINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 6-CHLOROTHYMINE manufacturers
- Product
- 6-CHLOROTHYMINE 1627-28-7
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1000kg
- Release date
- 2025-12-24
- Product
- 6-CHLOROTHYMINE 1627-28-7
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-12-08
- Product
- 6-CHLOROTHYMINE 1627-28-7
- Price
- US $5.00/KG
- Min. Order
- 1KG
- Purity
- 85.0-99.9%
- Supply Ability
- 100g,1kg,5kg
- Release date
- 2019-09-10