BT11
- Product Name
- BT11
- CAS No.
- 1912399-75-7
- Chemical Name
- BT11
- Synonyms
- BT11;Omilancor;BT11;BT 11;BT-11, >98%;Omilancor (BT-11);Omilancor (BT-11) ，S6419;piperazine-1,4-diylbis((6-(1H-benzo[d]imidazol-2-yl)pyridin-2-yl)methanone);Methanone, 1,1'-(1,4-piperazinediyl)bis[1-[6-(1H-benzimidazol-2-yl)-2-pyridinyl]-;[4-[6-(1~{H}-benzimidazol-2-yl)pyridine-2-carbonyl]piperazin-1-yl]-[6-(1~{H}-benzimidazol-2-yl)pyridin-2-yl]methanone
- CBNumber
- CB01424535
- Molecular Formula
- C30H24N8O2
- Formula Weight
- 528.56
- MOL File
- 1912399-75-7.mol
BT11 Property
- Boiling point:
- 923.4±75.0 °C(Predicted)
- Density
- 1.424±0.06 g/cm3(Predicted)
- solubility
- DMSO: Soluble: =10 mg/ml
- form
- Solid
- pka
- 10.24±0.10(Predicted)
N-Bromosuccinimide Price
- Product number
- CD35000157
- Product name
- BT-11
- Purity
- 98%
- Packaging
- 25mg
- Price
- $118
- Updated
- 2021/12/16
- Product number
- CD35000157
- Product name
- BT-11
- Purity
- 98%
- Packaging
- 100mg
- Price
- $395
- Updated
- 2021/12/16
- Product number
- DC10460
- Product name
- BT-11
- Purity
- >98%
- Packaging
- 100mg
- Price
- $550
- Updated
- 2021/12/16
- Product number
- DC10460
- Product name
- BT-11
- Purity
- >98%
- Packaging
- 1g
- Price
- $1900
- Updated
- 2021/12/16
BT11 Chemical Properties,Usage,Production
Uses
BT-11 is an orally available LANCL2 binding compound for treating inflammatory bowel disease.
Biological Activity
BT11 is an orally active compound that binds to lanthionine synthetase C-like 2 (LANCL2) with a Kd value of 7.7 μM and can be used for the treatment of inflammatory bowel disease.
in vivo
Oral administration of 8 mg/kg/day BT-11 to mice attenuates colitis. In the drug safety testing experiment in rats, oral high concentrations of BT-11 have good safety (detection concentration up to 1000 mg/kg/day).
target
| Target | Value |
| LANCL2 () |