ChemicalBook > CAS DataBase List > 20-DEOXYINGENOL
20-DEOXYINGENOL
- Product Name
- 20-DEOXYINGENOL
- CAS No.
- 54706-99-9
- Chemical Name
- 20-DEOXYINGENOL
- Synonyms
- 20-DEOXYINGENOL;20-Deoxyingenol, >98%;20-deoxyingenol 54706-99-9;20-DEOXYINGENOL, 10 mM in DMSO;(1aR,10aα)-1a,2,5,5a,6,9,10,10a-Octahydro-5β,5aβ,6β-trihydroxy-1,1,4,7,9α-pentamethyl-1H-2α,8aα-methanocyclopenta[a]cyclopropa[e]cyclodecen-11-one;(1aR,2S,5R,5aS,6S,8aS,9R,10aR)-5,5a,6-Trihydroxy-1,1,4,7,9-pentamethyl-1a,2,5,5a,6,9,10,10a-octahydro-1H-2,8a-methanocyclopenta[a]cyclopropa[e][10]annulen-11-one;1H-2,8a-Methanocyclopenta[a]cyclopropa[e]cyclodecen-11-one, 1a,2,5,5a,6,9,10,10a-octahydro-5,5a,6-trihydroxy-1,1,4,7,9-pentamethyl-, (1aR,2S,5R,5aS,6S,8aS,9R,10aR)-
- CBNumber
- CB01430727
- Molecular Formula
- C20H28O4
- Formula Weight
- 332.43
- MOL File
- 54706-99-9.mol
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20-DEOXYINGENOL Property
- Melting point:
- 208-209℃(Decomposition)
- Boiling point:
- 470.5±45.0 °C(Predicted)
- Density
- 1.26±0.1 g/cm3 (20 ºC 760 Torr)
- storage temp.
- Store at -20°C
- solubility
- DMSO : 50 mg/mL (150.41 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
- form
- Powder
- pka
- 12.21±0.70(Predicted)
- color
- White to off-white
- InChIKey
- FOSYZKSOJUQLTD-NHPMXQBPSA-N
- SMILES
- [C@@]12(O)[C@@H](O)C(C)=C[C@@]31C(=O)[C@@]([H])(C=C(C)[C@H]2O)[C@]1([H])C(C)(C)[C@]1([H])C[C@H]3C
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H318Causes serious eye damage
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 33225
- Product name
- 20-Deoxyingenol
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $41
- Updated
- 2026/04/30
Cayman Chemical
- Product number
- 33225
- Product name
- 20-Deoxyingenol
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $128
- Updated
- 2026/04/30
Cayman Chemical
- Product number
- 33225
- Product name
- 20-Deoxyingenol
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $235
- Updated
- 2026/04/30
Cayman Chemical
- Product number
- 33225
- Product name
- 20-Deoxyingenol
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $437
- Updated
- 2026/04/30
Biorbyt Ltd
- Product number
- orb1301581
- Product name
- 20-DEOXYINGENOL
- Purity
- 99.98%(Mayvarybetweenbatches)
- Packaging
- 1mg
- Price
- $80
- Updated
- 2026/05/06
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20-DEOXYINGENOL Chemical Properties,Usage,Production
Uses
20-Deoxyingenol is a diterpene derivative of Ingenol (I655795), the analogue of Ingenol 3-Angelate (I655800), which has anti-tumor activity when used topically for the treatment of actinic keratosis.
in vivo
20-Deoxyingenol (20 mg/kg/d; i.p. for 8 weeks) alleviates the progression of OA in the DMM model in mice[2].
| Animal Model: | 10-week-old C57BL/6 male wild-type (WT) mice with destabilization of the medial meniscus (DMM)[2] |
| Dosage: | 20 mg/kg |
| Administration: | I.p. one time per day, for eight consecutive weeks |
| Result: | Had a slightly wider joint space and reduced bone density and calcification compared with the DMM group. Inhibited the decrease in the thickness of hyaline cartilage (HC), and alleviated the disorder and hypertrophy of chondrocytes in the joint tissues of mice after DMM surgery. Had less erosion on the surface of the articular cartilage and more proteoglycan content. Had more positive staining points of LAMP1 and LC3 II, and less cleaved-caspase3 and P16INK4a. Increased the nuclear level of TFEB. |
20-DEOXYINGENOL Preparation Products And Raw materials
Raw materials
Preparation Products
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20-DEOXYINGENOL Suppliers
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- China
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View Lastest Price from 20-DEOXYINGENOL manufacturers
NanJing Spring & Autumn Biological Engineering CO., LTD.
- Product
- 20-deoxyingenol 54706-99-9 54706-99-9
- Price
- US $42.00/g
- Min. Order
- 10mg
- Purity
- 98.00% HPLC
- Supply Ability
- 1000.00 kgs
- Release date
- 2019-06-27
Career Henan Chemical Co
- Product
- 20-DEOXYINGENOL 54706-99-9
- Price
- US $2.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2018-12-23
54706-99-9, 20-DEOXYINGENOLRelated Search:
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