4-BROMO-3-FLUOROBENZOIC ACID ETHYL ESTER
- Product Name
- 4-BROMO-3-FLUOROBENZOIC ACID ETHYL ESTER
- CAS No.
- 1130165-74-0
- Chemical Name
- 4-BROMO-3-FLUOROBENZOIC ACID ETHYL ESTER
- Synonyms
- Ethyl 4-bromo-3-fluorobenzoat;4-BROMO-3-FLUOROBENZOIC ACID ETHYL ESTER;Benzoic acid, 4-bromo-3-fluoro-, ethyl ester
- CBNumber
- CB01484856
- Molecular Formula
- C9H8BrFO2
- Formula Weight
- 247.06
- MOL File
- 1130165-74-0.mol
4-BROMO-3-FLUOROBENZOIC ACID ETHYL ESTER Property
- Boiling point:
- 285.4±25.0 °C(Predicted)
- Density
- 1.504±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- form
- liquid
- color
- Clear, colourless
- EPA Substance Registry System
- Benzoic acid, 4-bromo-3-fluoro-, ethyl ester (1130165-74-0)
Safety
- HS Code
- 2916399090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation
H401Toxic to aquatic life
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P272Contaminated work clothing should not be allowed out of the workplace.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- E900493
- Product name
- Ethyl4-Bromo-3-fluorobenzoate
- Packaging
- 25mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- CS-0041471
- Product name
- Ethyl4-bromo-3-fluorobenzoate
- Packaging
- 1g
- Price
- $61
- Updated
- 2021/12/16
- Product number
- PC53348
- Product name
- Ethyl 4-bromo-3-fluorobenzoate
- Packaging
- 1g
- Price
- $68
- Updated
- 2021/12/16
- Product number
- 2623-B-35
- Product name
- Ethyl 4-bromo-3-fluorobenzoate
- Purity
- 99%
- Packaging
- 1g
- Price
- $80
- Updated
- 2021/12/16
- Product number
- 1496CZ
- Product name
- Ethyl4-bromo-3-fluorobenzoate
- Packaging
- 250mg
- Price
- $99
- Updated
- 2021/12/16
4-BROMO-3-FLUOROBENZOIC ACID ETHYL ESTER Chemical Properties,Usage,Production
Synthesis
64-17-5
153556-42-4
1130165-74-0
To a suspension of 4-bromo-3-fluorobenzoic acid (15.0 g) in anhydrous ethanol (230 mL) was slowly added concentrated sulfuric acid (8.0 mL). The reaction mixture was placed in a 60°C oil bath and stirred for 66 hours. After completion of the reaction, it was cooled to room temperature and the solvent was removed by rotary evaporator under reduced pressure. The residue was washed with 1 N sodium hydroxide solution (70 mL) and subsequently extracted with ethyl acetate (500 mL). The organic phase was washed sequentially with water (250 mL) and saturated saline (250 mL), dried over anhydrous magnesium sulfate, filtered and concentrated under reduced pressure. Ethyl 4-bromo-3-fluorobenzoate was obtained as a light yellow solid (17.0 g, quantitative yield). Mass spectral analysis showed M/Z (M [79 Br] + H)+ = 247.
References
[1] Patent: EP2210891, 2010, A1. Location in patent: Page/Page column 17-18
[2] Journal of Medicinal Chemistry, 2009, vol. 52, # 6, p. 1540 - 1545
4-BROMO-3-FLUOROBENZOIC ACID ETHYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-BROMO-3-FLUOROBENZOIC ACID ETHYL ESTER manufacturers
- Product
- 4-BROMO-3-FLUOROBENZOIC ACID ETHYL ESTER 1130165-74-0
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2020-02-12