ChemicalBook > CAS DataBase List > 4-ETHYL-3-NITROANILINE

4-ETHYL-3-NITROANILINE

Product Name
4-ETHYL-3-NITROANILINE
CAS No.
51529-96-5
Chemical Name
4-ETHYL-3-NITROANILINE
Synonyms
4-ETHYL-3-NITROANILINE;3-Nitro-4-ethylaniline;4-ethyl-3-nitrobenzeneamine;Benzenamine, 4-ethyl-3-nitro-;4-Ethyl-3-nitroaniline 4-ethyl-3-nitroaniline
CBNumber
CB01495058
Molecular Formula
C8H10N2O2
Formula Weight
166.18
MOL File
51529-96-5.mol
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4-ETHYL-3-NITROANILINE Property

Melting point:
44-45 °C
Boiling point:
305.7±22.0 °C(Predicted)
Density 
1.218±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
2.90±0.10(Predicted)
Appearance
Light yellow to yellow Solid
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Safety

HS Code 
2921490090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
E939773
Product name
4-Ethyl-3-nitroaniline
Packaging
100mg
Price
$90
Updated
2021/12/16
TRC
Product number
E939773
Product name
4-Ethyl-3-nitroaniline
Packaging
500mg
Price
$350
Updated
2021/12/16
AK Scientific
Product number
5009DA
Product name
4-Ethyl-3-nitroaniline
Packaging
5g
Price
$718
Updated
2021/12/16
Chemenu
Product number
CM193752
Product name
4-ethyl-3-nitroaniline
Purity
95+%
Packaging
10g
Price
$729
Updated
2021/12/16
Alichem
Product number
51529965
Product name
4-Ethyl-3-nitroaniline
Packaging
25g
Price
$1199
Updated
2021/12/16
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4-ETHYL-3-NITROANILINE Chemical Properties,Usage,Production

Synthesis

589-16-2

51529-96-5

Step 1: 4-Ethylaniline (10.3 mL, 82.5 mmol) was slowly added dropwise to 96% sulfuric acid (63 mL), and the reaction system was cooled to 8°C and ensured that the temperature was maintained below 10°C. After the dropwise addition was completed, the reaction mixture was further cooled to -5 °C, followed by the slow addition of a mixed acid consisting of 100% nitric acid (4 mL) and 96% sulfuric acid (10 mL), controlling the reaction temperature below 0 °C. The reaction mixture was stirred continuously at -5°C for 1 hour. Upon completion of the reaction, the mixture was slowly poured into ice water (200 mL), precipitated, filtered and washed with water. The resulting solid was resuspended in water (100 mL) and neutralized to neutral with 35% ammonium hydroxide solution. The precipitate was collected by filtration and dried in an oven to give the light brown solid product 4-ethyl-3-nitroaniline (10 g, 73% yield). The product was characterized by 1H NMR (400 MHz, DMSO-d6): δ 1.11 (t, J = 7.45 Hz, 3H), 2.63 (q, J = 7.45 Hz, 2H), 5.53 (s, 2H), 6.81 (dd, J = 8.30, 2.44 Hz, 1H), 7.04 (d, J = 2.44 Hz, 1H), 7.11 ( d, J = 8.30 Hz, 1H).

References

[1] Patent: WO2012/139930, 2012, A1. Location in patent: Page/Page column 72
[2] Patent: WO2012/143248, 2012, A1. Location in patent: Page/Page column 23
[3] Patent: WO2014/19908, 2014, A2. Location in patent: Page/Page column 32
[4] Patent: US2014/51708, 2014, A1. Location in patent: Paragraph 0717-0719
[5] Journal of the Chemical Society, 1930, p. 252,255

4-ETHYL-3-NITROANILINE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 4-ETHYL-3-NITROANILINE manufacturers

Honest Joy Holdings Limited
Product
4-Ethyl-3-nitroaniline 51529-96-5
Price
US $0.00/KG
Min. Order
1KG
Purity
99.3%
Supply Ability
100 tons
Release date
2022-01-14

51529-96-5, 4-ETHYL-3-NITROANILINERelated Search:


  • 4-ETHYL-3-NITROANILINE
  • 4-ethyl-3-nitrobenzeneamine
  • 3-Nitro-4-ethylaniline
  • Benzenamine, 4-ethyl-3-nitro-
  • 4-Ethyl-3-nitroaniline 4-ethyl-3-nitroaniline
  • 51529-96-5