2-AMINO-4-(3,4-DIMETHOXY-PHENYL)-THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER

Product Name: 2-AMINO-4-(3,4-DIMETHOXY-PHENYL)-THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER
CAS No.: 15854-12-3
Chemical Name: 2-AMINO-4-(3,4-DIMETHOXY-PHENYL)-THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER
Synonyms: aPKC-IN-1;Ethyl 2-amino-4-(3,4-dimethoxyphenyl)-3-thiophenecarboxylate;2-amino-4-(3,4-dimethoxyphenyl)-3-thiophenecarboxylic acid ethyl ester;3-Thiophenecarboxylic acid, 2-amino-4-(3,4-dimethoxyphenyl)-, ethyl ester
CBNumber: CB01499874
Molecular Formula: C15H17NO4S
Formula Weight: 307.36
MOL File: 15854-12-3.mol

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2-AMINO-4-(3,4-DIMETHOXY-PHENYL)-THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER Property

Boiling point:: 437.3±45.0 °C(Predicted)
Density: 1.234±0.06 g/cm3(Predicted)
pka: -0.29±0.10(Predicted)
form: solid

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Safety

Hazard Codes: Xn
Risk Statements: 22-41
Safety Statements: 26-39
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: OTV000270
Product name: Ethyl 2-amino-4-(3,4-dimethoxyphenyl)-3-thiophenecarboxylate
Purity: Aldrich
Packaging: 1g
Price: $216
Updated: 2025/07/31

TRC

Product number: A597175
Product name: 2-Amino-4-(3,4-dimethoxy-phenyl)-thiophene-3-carboxylicacidethylester
Packaging: 250mg
Price: $210
Updated: 2021/12/16

Matrix Scientific

Product number: 028952
Product name: Ethyl 2-amino-4-(3,4-dimethoxyphenyl)thiophene-3-carboxylate
Packaging: 500mg
Price: $126
Updated: 2021/12/16

AK Scientific

Product number: 5006AD
Product name: Ethyl2-amino-4-(3,4-dimethoxyphenyl)thiophene-3-carboxylate
Packaging: 500mg
Price: $220
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0020260
Product name: 2-AMINO-4-(3,4-DIMETHOXY-PHENYL)-THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER
Purity: 95.00%
Packaging: 1G
Price: $677.91
Updated: 2021/12/16

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2-AMINO-4-(3,4-DIMETHOXY-PHENYL)-THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER Chemical Properties,Usage,Production

Uses

aPKC-IN-1 (compound 1) is an atypical protein kinase C (aPKCζ) inhibitor. aPKC-IN-1 can be used for the study of a host of diseases involving increased vascular permeability and inflammation[1].

References

[1] Paul M Titchenellm, et al. Synthesis and structure-activity relationships of 2-amino-3-carboxy-4-phenylthiophenes as novel atypical protein kinase C inhibitors. Bioorg Med Chem Lett. 2013 May 15;23(10):3034-8. DOI:10.1016/j.bmcl.2013.03.019

2-AMINO-4-(3,4-DIMETHOXY-PHENYL)-THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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2-AMINO-4-(3,4-DIMETHOXY-PHENYL)-THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER Suppliers

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15854-12-3, 2-AMINO-4-(3,4-DIMETHOXY-PHENYL)-THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTERRelated Search:

Propyl 2-amino-4-(3,4-dimethoxyphenyl)thiophene-3-carboxylate 2-AMINO-4-(3,4-DIMETHOXY-PHENYL)-THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER AKOS B000853 ETHYL 4-(3,4-DIMETHOXYPHENYL)-2-(2-PHENYLACETAMIDO)THIOPHENE-3-CARBOXYLATE AURORA 22059 ETHYL 2-[(4-BROMOBENZOYL)AMINO]-4-(3,4-DIMETHOXYPHENYL)THIOPHENE-3-CARBOXYLATE AURORA 23079 AURORA 22183 AURORA 22727 ETHYL 2-[(2-CHLOROBENZOYL)AMINO]-4-(3,4-DIMETHOXYPHENYL)THIOPHENE-3-CARBOXYLATE AURORA 22129 AURORA 22800 2-(2-CHLORO-ACETYLAMINO)-4-(3,4-DIMETHOXY-PHENYL)-THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER AURORA 11642 ETHYL 2-(BUTYRYLAMINO)-4-(3,4-DIMETHOXYPHENYL)THIOPHENE-3-CARBOXYLATE AURORA 22503 ETHYL 4-(3,4-DIMETHOXYPHENYL)-2-PIVALAMIDOTHIOPHENE-3-CARBOXYLATE AURORA 23065

Ethyl 2-amino-4-(3,4-dimethoxyphenyl)-3-thiophenecarboxylate

2-amino-4-(3,4-dimethoxyphenyl)-3-thiophenecarboxylic acid ethyl ester

3-Thiophenecarboxylic acid, 2-amino-4-(3,4-dimethoxyphenyl)-, ethyl ester

aPKC-IN-1

15854-12-3