ChemicalBook > CAS DataBase List > 6-BROMO-4-FLUORO-1H-INDAZOLE

6-BROMO-4-FLUORO-1H-INDAZOLE

Product Name
6-BROMO-4-FLUORO-1H-INDAZOLE
CAS No.
885520-23-0
Chemical Name
6-BROMO-4-FLUORO-1H-INDAZOLE
Synonyms
BROMOFLUOROINDAZOLE;4-Fluoro-6-bromo-indazole;6-Bromo-4-fluoro-2H-indazole;4-fluoro-6-bromo-1H-indazole;1H-Indazole, 6-bromo-4-fluoro-;6-Bromo-4-fluoro-1H-indazole
CBNumber
CB01501986
Molecular Formula
C7H4BrFN2
Formula Weight
215.02
MOL File
885520-23-0.mol
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6-BROMO-4-FLUORO-1H-INDAZOLE Property

Boiling point:
331.3±22.0 °C(Predicted)
Density 
1.861±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
12.00±0.40(Predicted)
form 
crystalline powder
color 
Yellow
InChI
InChI=1S/C7H4BrFN2/c8-4-1-6(9)5-3-10-11-7(5)2-4/h1-3H,(H,10,11)
InChIKey
IHCPAAHPKILIIC-UHFFFAOYSA-N
SMILES
N1C2=C(C(F)=CC(Br)=C2)C=N1
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Safety

Hazard Codes 
T
Risk Statements 
25
Safety Statements 
45
RIDADR 
2811
WGK Germany 
3
HazardClass 
6.1
PackingGroup 
HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

Precautionary statements

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SYX00189
Product name
6-Bromo-4-fluoro-1H-indazole
Purity
Aldrich
Packaging
1g
Price
$497
Updated
2025/07/31
TRC
Product number
B687658
Product name
6-Bromo-4-fluoro-1H-indazole
Packaging
250mg
Price
$70
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB53853
Product name
6-Bromo-4-fluoro-1H-indazole
Packaging
2g
Price
$300
Updated
2021/12/16
AK Scientific
Product number
J90393
Product name
6-Bromo-4-fluoro-1H-indazole
Packaging
250mg
Price
$42
Updated
2021/12/16
Apolloscientific
Product number
PC200355
Product name
6-Bromo-4-fluoro-1H-indazole
Purity
97%
Packaging
250mg
Price
$47
Updated
2021/12/16
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6-BROMO-4-FLUORO-1H-INDAZOLE Chemical Properties,Usage,Production

Synthesis

537013-51-7

885520-23-0

4-Bromo-2,6-difluorobenzaldehyde (CAS 537013-51-7, 442.0 mg, 2.00 mmol) was suspended in ethylene glycol (10 mL) at room temperature, and hydrazine monohydrate (0.19 mL, 4.00 mmol) was slowly added with stirring. The reaction mixture was heated to 95 °C under nitrogen protection and maintained at this temperature for 2 hours. Upon completion of the reaction, the mixture was cooled to 5 °C and diluted with deionized water. Subsequently, the reaction solution was extracted with ethyl acetate, the organic phase was dried with anhydrous sodium sulfate and concentrated under reduced pressure to afford the target product 6-bromo-4-fluoro-1H-indazole (430.0 mg, 100% yield) as a yellow solid.

References

[1] Bioorganic and Medicinal Chemistry, 2016, vol. 24, # 23, p. 6194 - 6205
[2] Journal of Medicinal Chemistry, 2017, vol. 60, # 7, p. 3187 - 3197
[3] Patent: US2015/99782, 2015, A1. Location in patent: Paragraph 0225; 0226

6-BROMO-4-FLUORO-1H-INDAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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6-BROMO-4-FLUORO-1H-INDAZOLE Suppliers

Changzhou Xuanye Technology Co., Ltd
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15195022192
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279776773@qq.com
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China
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Shanghai Xuerong Chemical Technology Co., LTD
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Jinan Trio PharmaTech Co., Ltd.
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Shanghai Sphchem Co., Ltd.
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Tianjin Derchemist Science & Technology Co., Ltd.
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China
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View Lastest Price from 6-BROMO-4-FLUORO-1H-INDAZOLE manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
6-BROMO-4-FLUORO-1H-INDAZOLE 885520-23-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
6-BROMO-4-FLUORO-1H-INDAZOLE 885520-23-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09