Dimethocaine Hydrochloride

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Dimethocaine Hydrochloride

Product Name: Dimethocaine Hydrochloride
CAS No.: 553-63-9
Chemical Name: Dimethocaine Hydrochloride
Synonyms: diMethocaine hcl;Larocaine HCl;Larocaine hydrochloride;Dimethylcaine hydrochloride;3-(diethylamino)-2;Dimethyl hydrochloride;Dimethocaine hydrochloride;Dimethocaine/Larocaine hcl;1-Propanol,3-(diethylamino)-2;3-Diethylamino-2,2-dimethylpropyl p-amin...
CBNumber: CB01509593
Molecular Formula: C16H26N2O2.ClH
Formula Weight: 314.854
MOL File: 553-63-9.mol

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Dimethocaine Hydrochloride Property

Melting point:: 195-196℃
storage temp.: Refrigerator
solubility: DMSO (Slightly), Water (Slightly)
form: Solid
color: White to Pale Beige
InChI: InChI=1S/C16H26N2O2.ClH/c1-5-18(6-2)11-16(3,4)12-20-15(19)13-7-9-14(17)10-8-13;/h7-10H,5-6,11-12,17H2,1-4H3;1H
InChIKey: WWTWKTDXBNHESE-UHFFFAOYSA-N
SMILES: C1(=CC=C(N)C=C1)C(=O)OCC(C)(C)CN(CC)CC.Cl

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Safety

Toxicity: MLD in mice, rabbits (g/kg): 0.30, 0.15 s.c.; 0.04, 0.015 i.v. (Hirschfelder, Bieter)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 11159
Product name: Dimethocaine (hydrochloride)
Purity: ≥98%
Packaging: 1mg
Price: $62
Updated: 2024/03/01

Cayman Chemical

Product number: 11159
Product name: Dimethocaine (hydrochloride)
Purity: ≥98%
Packaging: 5mg
Price: $270
Updated: 2024/03/01

Cayman Chemical

Product number: 11159
Product name: Dimethocaine (hydrochloride)
Purity: ≥98%
Packaging: 10mg
Price: $477
Updated: 2024/03/01

Usbiological

Product number: 010123
Product name: Dimethocaine Hydrochloride
Packaging: 25mg
Price: $460
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD22163
Product name: 3-Diethylamino-2,2-dimethylpropyl p-aminobenzoate hydrochloride
Packaging: 50g
Price: $430
Updated: 2021/12/16

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Dimethocaine Hydrochloride Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

A local anesthetic with stimulant properties. Studies have shown its potency to be about half that of Cocaine (C633500).

Uses

Dimethocaine Hydrochloride is a local anesthetic, because of its similarity in action to cocaine, has potential for abuse. This compound completely inhibits dopamine uptake in rat striatal synaptosomes with an IC50 value of 1.2 μM comparable to that of cocaine (IC50 = 0.7 μM). As a result, dimethocaine dose-dependently substitutes for cocaine in drug discrimination tests in rats and rhesus monkeys. This product is intended for forensic and research purposes.[Cayman Chemical]

Application

Dimethocaine Hydrochloride is a drug that belongs to the amide class. It has been shown to have significant effects on neuronal function in vivo, as well as on dopamine neurotransmission in vitro. It is also a substrate for uptake by the dopamine transporter and can inhibit locomotor activity in rats, suggesting it may be a potential therapeutic agent for the treatment of Parkinson's disease. It has been shown to be effective against cocaine addiction and can reduce angiogenic factors in vivo. The drug also interacts with other drugs, including synthetic cannabinoids and amphetamines, which are metabolized by CYP2B6 enzymes. These interactions may result in reduced efficacy of Dimethocaine Hydrochloride therapy.

Side effects

Its positive effects are euphoria, stimulation, increased talkativeness and mood lift. However, because the drug acts similar as cocaine, it has comparable negative side effects. These side effects include: tachycardia, difficulty with breathing, pain on the chest, vasoconstriction, insomnia, paranoia and anxiety.

Dimethocaine Hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Dimethocaine Hydrochloride Suppliers

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View Lastest Price from Dimethocaine Hydrochloride manufacturers

Dorne Chemical Technology co. LTD

Product: Dimethocaine Hydrochloride 553-63-9
Price: US $10.00/ASSAYS
Min. Order: 1ASSAYS
Purity: 99%
Supply Ability: 1 ton
Release date: 2024-03-26

Hebei Yanxi Chemical Co., Ltd.

Product: Dimethocaine Hydrochloride 553-63-9
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5000kg
Release date: 2023-08-09

Hebei Ganmiao New material Technology Co., LTD

Product: Dimethocaine Hydrochloride 553-63-9
Price: US $10.00-8.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-06-06

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553-63-9

C16H26N2O2HCl

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