7-BROMO-1-BENZOFURAN-2-CARBOXYLICACID
Application- Product Name
- 7-BROMO-1-BENZOFURAN-2-CARBOXYLICACID
- CAS No.
- 550998-59-9
- Chemical Name
- 7-BROMO-1-BENZOFURAN-2-CARBOXYLICACID
- Synonyms
- 7-Bromo-2-benzofurancarboxylic acid;2-Benzofurancarboxylic acid, 7-bromo-;7-BROMO-1-BENZOFURAN-2-CARBOXYLICACID
- CBNumber
- CB01511343
- Molecular Formula
- C9H5BrO3
- Formula Weight
- 241.04
- MOL File
- 550998-59-9.mol
7-BROMO-1-BENZOFURAN-2-CARBOXYLICACID Property
- Boiling point:
- 370.9±22.0 °C(Predicted)
- Density
- 1.784±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 2.90±0.30(Predicted)
- Appearance
- Off-white to light yellow Solid
- CAS DataBase Reference
- 550998-59-9
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B680563
- Product name
- 7-Bromobenzofuran-2-carboxylicacid
- Packaging
- 50mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- FB150038
- Product name
- 7-Bromo-1-benzofuran-2-carboxylicacid
- Packaging
- 50mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- 2H21-9-0D
- Product name
- 7-Bromobenzofuran-2-carboxylicacid
- Packaging
- 250mg
- Price
- $88
- Updated
- 2021/12/16
- Product number
- FB150038
- Product name
- 7-Bromo-1-benzofuran-2-carboxylicacid
- Packaging
- 100mg
- Price
- $113
- Updated
- 2021/12/16
- Product number
- 096933
- Product name
- 7-Bromo-1-benzofuran-2-carboxylic acid
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $182
- Updated
- 2021/12/16
7-BROMO-1-BENZOFURAN-2-CARBOXYLICACID Chemical Properties,Usage,Production
Application
7-Bromobenzofuran-2-carboxylic acid can be used as a pharmaceutical synthesis intermediate.
Synthesis
Method 1, two-step synthesis. 1) Preparation of 3-bromo-2-hydroxybenzaldehyde: 2-Bromophenol is heated under reflux with anhydrous magnesium chloride, paraformaldehyde, and triethylamine in acetonitrile. Work-up yields the product. 2) Preparation of 7-bromobenzofuran-2-carboxylic acid: The product from step 1 (crude) is heated with methyl chloroacetate, tetra-n-butylammonium iodide, and potassium carbonate. Water and THF are then added, followed by potassium hydroxide, and the mixture is stirred at room temperature overnight. Subsequent acidification and extraction/purification yield the product.
7-BROMO-1-BENZOFURAN-2-CARBOXYLICACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 7-BROMO-1-BENZOFURAN-2-CARBOXYLICACID manufacturers
- Product
- 7-BROMO-1-BENZOFURAN-2-CARBOXYLICACID 550998-59-9
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 85.0-99.8%
- Supply Ability
- 20tons
- Release date
- 2020-10-29